Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Richard N. Rossan"'
Autor:
Ayoade M.J. Oduola, Dennis E. Kyle, L. A. Salako, Richard N. Rossan, Brian G. Schuster, Wilbur K. Milhous, Thomas G. Brewer, Lucia Gerena, A. Sowunmi
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 58:625-629
The effect of combining promethazine with chloroquine was examined against Plasmodium falciparum in vitro in the Aotus-P. falciparum model and in bioassays from volunteers given promethazine. The combination of chloroquine plus promethazine (1 x 10(-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155d352857f0130e706cc56967807dec
https://doi.org/10.4269/ajtmh.1998.58.625
https://doi.org/10.4269/ajtmh.1998.58.625
Publikováno v:
Malaria Journal
Background In vitro evidence indicates that tetrandrine (TT) can potentiate the action of chloroquine 40-fold against choloquine-resistant Plasmodium falciparum. The key question emanating from that study is “would tetrandine and chloroquine be hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f183d23d5eef51f8bffb51eac8131ac
https://doi.org/10.1186/1475-2875-12-117
https://doi.org/10.1186/1475-2875-12-117
Autor:
Arba L. Ager, L Brown, Brian G. Schuster, P McGreevy, William Y. Ellis, Susan L. Andersen, Richard N. Rossan, Judith Berman, Robert E. Miller
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:1753-1756
WR 243251 is a dihydroacridinedione that was evaluated for antimalarial blood schizonticidal activity in vitro and in vivo. The in vitro doses calculated to kill 50% of organisms were 11 nM for a chloroquine-susceptible, mefloquine-resistant standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd222bc1526436c15d3c49d009d0f1c
https://doi.org/10.1128/aac.38.8.1753
https://doi.org/10.1128/aac.38.8.1753
Autor:
T. R. Sweeney, Arba L. Ager, Craig J. Canfield, Wilbur K. Milhous, David P. Jacobus, N. J. Lewis, Richard N. Rossan
Publikováno v:
The American journal of tropical medicine and hygiene. 49(1)
A new, orally-active inhibitor of dihydrofolic acid reductase (DHFR), PS-15 (N-(3-(2,4,5-trichlorophenoxy)propyloxy)-N′-(1-methylethyl)-imidocarbonimidicdiamide hydrochloride), has significant activity against drug-resistant Plasmodium falciparum.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a485e7b85277a3a4cda00158fd73d66
https://pubmed.ncbi.nlm.nih.gov/8352384
https://pubmed.ncbi.nlm.nih.gov/8352384
Publikováno v:
The American journal of tropical medicine and hygiene. 48(1)
An Aotus-Plasmodium falciparum model was used to determine if chloro- quine resistance could be reversed in vivo. The putative resistance modulators tested all reverse chloroquine resistance in vitro and included verapamil, chlorpromazine, proch- lor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c349678dad204b1f59917c2a1bf5bfe4
https://pubmed.ncbi.nlm.nih.gov/8427381
https://pubmed.ncbi.nlm.nih.gov/8427381
Autor:
Henry N. Fremount, Richard N. Rossan
Publikováno v:
Transactions of the American Microscopical Society. 110:361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2112f271ff850188c854728a5b7b0b71
https://doi.org/10.2307/3226773
https://doi.org/10.2307/3226773
Autor:
Richard N. Rossan, Henry N. Fremount
Publikováno v:
The Journal of Parasitology. 76:428
Organ distribution of developing trophozoite- and schizont-infected erythrocytes of Plasmodium vivax and night monkeys, Aotus lemurinus lemurinus, and squirrel monkeys, Saimiri sciureus, was determined. The primary site for the infection in both spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::520571787be624a567c569b025365751
https://doi.org/10.2307/3282681
https://doi.org/10.2307/3282681
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 26:837-849
The experiments described in this report have dealt with the dimensions of therapeutic potentiation achieved when combinations of pyrimethamine and sulfadiazine were administered to rhesus monkeys infected with a drug-susceptible strain of Plasmodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cb510e31d6574ee1c38e7ff3aee6db
https://doi.org/10.4269/ajtmh.1977.26.837
https://doi.org/10.4269/ajtmh.1977.26.837
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:612-645
This report summarizes the results of a longitudinal study of the characteristics of untreated infections with trophozoites and sporozoites of the M, B, and Ro strains of P. cynomolgi. The pre-initial-peak phases of infections with trophozoites of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a085228ab5a62b7b5b1fc9b4e69c8f9
https://doi.org/10.4269/ajtmh.1982.31.612
https://doi.org/10.4269/ajtmh.1982.31.612