Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Richard M. Rohan"'
Autor:
Michael S Rogers, Victor Boyartchuk, Richard M Rohan, Amy E Birsner, William F Dietrich, Robert J D'Amato
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35237 (2012)
Angiogenesis is the process by which new blood vessels are formed from existing vessels. Mammalian populations, including humans and mice, harbor genetic variations that alter angiogenesis. Angiogenesis-regulating gene variants can result in increase
Externí odkaz:
https://doaj.org/article/3788edd0b3a041e68f35fae8e3eba6ff
Autor:
George A. Taylor, Christian M. Becker, Sarah Short, Judah Folkman, Robert J. D'Amato, Jason A. Efstathiou, David A. Sampson, Richard M. Rohan, Maria Rupnick
Publikováno v:
Fertility and Sterility. 84:1144-1155
Objective To determine whether endometriosis can be treated with the angiogenesis inhibitor endostatin and the effect of this treatment on fertility and reproduction. Design Pharmacologic intervention in a surgically induced model of endometriosis an
Publikováno v:
The FASEB Journal. 18:1050-1059
Angiogenesis is controlled by a balance between stimulatory growth factors and endogenous inhibitors. We propose that the balance of stimulators and inhibitors, as well as the general sensitivity of the endothelium to these factors, varies from indiv
Publikováno v:
The FASEB Journal. 17:1-18
Angiogenesis is regulated by the balance between angiogenic stimulators and inhibitors. Numerous reports have demonstrated that tumors induce aggressive angiogenesis by up-regulating the production of angiogenesis stimulating growth factors to overco
Autor:
John W. Fanton, Timothy M. Hazzard, Theodore A. Molskness, Richard M. Rohan, Richard L. Stouffer, Robert J. D'Amato
Publikováno v:
Endocrine. 17:199-206
Ovulation and conversion of the follicle into the corpus luteum involve remarkable changes in vascular permeability and neovascularization of the luteinizing granulosa layer. To evaluate the importance of these vascular events in follicle rupture and
Publikováno v:
Developmental Dynamics. 220:112-121
Vascular endothelial growth factor (VEGF), a factor that is critical for development of the vascular system in mouse embryos, exists as at least three isoforms, VEGF120, VEGF164, and VEGF188. The isoforms have different affinities for heparan sulfate
Publikováno v:
Nephron. 88:360-367
Aim: To examine the response of the insulinlike growth factor (IGF) system in the kidney during a state of extreme growth. Methods: We studied the mRNA expression of IGF-I, IGF-I receptor, and IGF-binding proteins (BP) using sensitive RNase protectio
Autor:
Muhammad Salmanullah, Michael K. Hise, Li Liu, Cinthia I. Drachenberg, John C. Papadimitriou, Richard M. Rohan
Publikováno v:
Renal Failure. 22:423-434
We studied gene expression for transforming growth factor (TGF)-alpha, epidermal growth factor (EGF), heparin binding (HB) EGF, and the EGF receptor following acute renal failure induced by mercuric chloride administration to gain insight into potent
Autor:
Eli Y. Adashi, Kristina Ruutiainen-Altman, Barry W. Donesky, Richard M. Rohan, Shahar Kol, Izhar Ben-Shlomo, Motomu Ando, Minoru Irahara
Publikováno v:
Biology of Reproduction. 61:274-282
It is hypothesized that the intraovarian interleukin (IL)-1 system plays a prominent role in the regulation of follicular development and ovulation. A central component of the intraovarian IL-1 system is the IL-1 receptor antagonist (IL-1RA), a prote
Publikováno v:
Journal of Endocrinology. 160:415-423
Transforming growth factor beta1 (TGFbeta1) acts as an inhibitor of the actions of interleukin-1beta (IL-1beta) in various organ systems. In order better to understand the inter|P-actions between these polypeptides in the ovary, we evaluated the effe