Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Richard M. Matsumoto"'
Publikováno v:
Clinical Pharmacokinetics. 37:273-287
Tazarotene (AGN 190168) is a new acetylenic retinoid which is effective for the topical treatment of patients with stable plaque psoriasis and mild to moderate acne vulgaris. Topical gel application provides direct delivery of tazarotene into the ski
Subchronic and Chronic Toxicity of Tazarotene Gel Following Topical Application in Hanford Miniswine
Autor:
Tami Saaty, I. Maged Ismail, Brian Baker, Richard M. Matsumoto, Bal Brar, Helen Sun, Diane D.-S. Tang-Liu
Publikováno v:
International Journal of Toxicology. 16:571-584
Tazarotene, a member of a novel class of synthetic acetylenic retinoids, is the first topical retinoid to demonstrate both efficacy and an acceptable patient tolerability profile in the treatment of psoriasis. The subchronic and chronic toxicity of t
Autor:
Nicholas J. Lowe, Jag Bhawan, John Sefton, Gerald D. Weinstein, Tania J. Phillips, Patricia S. Walker, James J. Leyden, Deborah A. Lew-Kaya, Richard M. Matsumoto, Jean Paul Ortonne, John R. Gibson, Sewon Kang
Publikováno v:
Archives of dermatology. 137(12)
Objective To assess the safety and efficacy of 4 concentrations of tazarotene cream in the treatment of facial photodamage. Design Prospective weekly multicenter, investigator-masked, randomized, parallel-group study. Setting University hospitals and
Autor:
Z. Dziewanowska, Zhang Jinkun, Maryanna Y. Morris, Lisa Greenberg, Ram P. Kapil, Victor J. Stevens, Jolene K. Berg, Richard M. Matsumoto
Publikováno v:
Blood. 112:3406-3406
LGD-4665, a new generation small molecule oral thrombopoietin (TPO) mimetic, increases platelet counts in a dose proportional manner, and is associated with a high safety margin in healthy subjects after single and multiple daily, or weekly doses. Ph
Autor:
Zhang Jinkun, Gordon R. Loewen, Barbara Newberry, James P. Doherty, Richard M. Matsumoto, Kristine Schindler, Jolene K. Berg, Z. Dziewanowska
Publikováno v:
Blood. 110:1298-1298
LGD-4665, an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. LGD-4665 is a highly selective and potent agonist of the TPO receptor and induces differentiation and proliferatio
Autor:
Arthur K. Cho, Richard M. Matsumoto
Publikováno v:
Biochemical Pharmacology. 31:105-108
These in vitro studies indicate that N -oxidation of N -hydroxyamphetamine (NOHA) by rat liver homogenates yields phenylacetone oxime (PAOx) as the major metabolite. This oxidation was NADPH and oxygen dependent but was not appreciably increased in m