Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Richard M. Jack"'
Autor:
Luke Barron, Jeremy S. Duffield, Sina A. Gharib, Mark L. Lupher, Richard M. Jack, Naoki Nakagawa, Sei Kameoka, Bryce G. Johnson, Allie M. Roach, Ivan G. Gomez
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic diseases. Here we show that recombinant human PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f01f978eb8bfdbb86fbb5989dd808e
https://europepmc.org/articles/PMC5135274/
https://europepmc.org/articles/PMC5135274/
Autor:
Fabrice Pierre, Lin Yu, Daniel S. Sem, Hugo O. Villar, Mark R. Hansen, Victor Hong, Richard Kho, Stephen M. Coutts, Henk Lang, Qing Dong, Edcon Chang, Xuemei Huang, Aurora D. Costache, Maurizio Pellecchia, David Meininger, Richard M. Jack, Chen-Ting Ma, Bonnie L. Bertolaet, Brian Baker
Publikováno v:
Chemistry & Biology. 11:185-194
Genomics-driven growth in the number of enzymes of unknown function has created a need for better strategies to characterize them. Since enzyme inhibitors have traditionally served this purpose, we present here an efficient systems-based inhibitor de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0b98c770547120dc17a27cefd71d5b
https://doi.org/10.1016/j.chembiol.2004.02.012
https://doi.org/10.1016/j.chembiol.2004.02.012
Publikováno v:
Journal of Proteome Research. 2:626-632
Enzymes that utilize nicotinamide adenine dinucleotide (NAD) or its 2'-phosphate derivative (NADP) are found throughout the kingdoms of life. These enzymes are fundamental to many biochemical pathways, including central intermediary metabolism and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449b682896f99decd6cd6bead0b4ab03
https://doi.org/10.1021/pr034051h
https://doi.org/10.1021/pr034051h
Autor:
Mark R. Hansen, Richard Kho, Daniel S. Sem, Joseph V. Newman, Richard M. Jack, Brian Baker, Hugo O. Villar
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 50:589-599
A novel method to organize protein structural information based solely on sequence is presented. The method clusters proteins into families that correlate with the three-dimensional protein structure and the conformation of the bound ligands. This pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e79dbcf179e06cafc4a69e01229003
https://doi.org/10.1002/prot.10316
https://doi.org/10.1002/prot.10316
Publikováno v:
Drug Discovery Today. 7:S35-S38
Triad Therapeutics’ proprietary technologies enable dramatic increases in both the speed of lead compound generation and the quality (binding affinity and specificity) of the compounds produced. Triad's approach, called Integrated Object-oriented P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b355b969d90cc1cc5737dfce93aed40
https://doi.org/10.1016/s1359-6446(01)02167-5
https://doi.org/10.1016/s1359-6446(01)02167-5
Publikováno v:
Immunity. 7(3):345-355
Molecular definition of the cellular receptor for the collagen domain of C1q has been elusive. We now report that C1q binds specifically to human CR1 (CD35), the leukocyte C3b/C4b receptor, and the receptor on erythrocytes for opsonized immune comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab16c2ca10bcc3eb710ca8930b1ab53
Autor:
Richard M. Jack, Tonya Barrett, Ce Wang, Anne Nicholson-Weller, Peter F. Weller, Sergei F. Barbashov
Publikováno v:
Blood. 85:2570-2578
The activity of hemolytically inactive C5b67, designated iC5b67, was evaluated as an agonist for functional responses of human polymorphonuclear leukocytes (PMN). C5b67 was formed from purified human complement components and decayed in phosphate-buf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa8d9ab32048c2d2f32d9a93d20aef7
https://doi.org/10.1182/blood.v85.9.2570.bloodjournal8592570
https://doi.org/10.1182/blood.v85.9.2570.bloodjournal8592570
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 54(6)
Erythrocyte complement receptor type 1 (E-CR1) is the main immune complex clearance mechanism in humans. Decreased E-CR1 expression is noted in certain inflammatory disorders. Recent evidence implicates inflammation in the pathogenesis of preeclampsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06596bbb4f1dea44645ed1de3c5cf582
https://pubmed.ncbi.nlm.nih.gov/16305660
https://pubmed.ncbi.nlm.nih.gov/16305660
Autor:
Daniel S, Sem, Bonnie, Bertolaet, Brian, Baker, Edcon, Chang, Aurora D, Costache, Stephen, Coutts, Qing, Dong, Mark, Hansen, Victor, Hong, Xuemei, Huang, Richard M, Jack, Richard, Kho, Henk, Lang, Chen-Ting, Ma, David, Meininger, Maurizio, Pellecchia, Fabrice, Pierre, Hugo, Villar, Lin, Yu
Publikováno v:
Chemistrybiology. 11(2)
Genomics-driven growth in the number of enzymes of unknown function has created a need for better strategies to characterize them. Since enzyme inhibitors have traditionally served this purpose, we present here an efficient systems-based inhibitor de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c605f35fbea1b7c1afc61da144168dc9
https://pubmed.ncbi.nlm.nih.gov/15123257
https://pubmed.ncbi.nlm.nih.gov/15123257
Autor:
Richard M. Jack
Publikováno v:
Nursing. 24:6-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0395e6b63578faa612bf3782cf3de2ec
https://doi.org/10.1097/00152193-199410000-00004
https://doi.org/10.1097/00152193-199410000-00004