Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Richard M. Hoar"'
Autor:
Pramod P. Reddy, James Mandell, R. LeFevre, R. F. Mankes, Christopher J. Calvano, Michael E. Moran, Richard M. Hoar
Publikováno v:
Teratology. 61:184-188
Umbilical cord length has long been investigated as a potential marker of intrauterine events that may place the neonate at risk for future adverse developmental sequelae. Experimentally, significantly shortened cords have been reported in associatio
Publikováno v:
Teratology. 57:64-69
A rare case of ectopic scrotum is described together with a review of the literature and a discussion of the embryological role of the gubernaculum in the formation and location of normal and ectopic scrota. We identified 16 reported cases of a supra
Autor:
Pramod P. Reddy, R. F. Mankes, Michael E. Moran, Christopher J. Calvano, James Mandell, Richard M. Hoar, R. LeFevre
Publikováno v:
Journal of Pediatric Surgery. 32:1302-1306
Background/Purpose: Fetal alcohol syndrome is characterized by facial dysmorphology, mental and growth retardation, and somatic anomalies including hydronephrosis. The authors sought to determine the influence of exogenous testosterone or estradiol o
Autor:
Richard M. Hoar
Publikováno v:
Journal of the American College of Toxicology. 14:11-20
There is a pervasive lack of understanding about the definition of a developmental toxicant and the experimental design necessary to differentiate between maternal toxicants and those uniquely, i.e., selectively, hazardous to the conceptus. Thus, the
Autor:
Richard M. Hoar, Mildred S. Christian
Publikováno v:
Congenital Anomalies. 32:117-124
The search for a carnivore as an addition to a multilevel test system for determining developmental toxicity has been extended to include the ferret. The following discussion is an effort to simplify the procedures which should be used with this spec
Autor:
Richard M. Hoar
Publikováno v:
Environmental Health Perspectives
A brief description of the basic patterns of mammalian organogenesis of the gastrointestinal and urogenital systems is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather on its
Autor:
RICHARD M. HOAR
Publikováno v:
Toxicological Sciences. 4:335-340
Publikováno v:
Journal of AOAC INTERNATIONAL. 62:840-843
New requirements by several regulatory agencies for testing the psychotoxic potential of new drugs, chemicals, and environmental contaminants raise unique problems. In order to assess intra- and interlaboratory reliability of behavioral tests a model
Autor:
Edward J. Lammer, Diane T. Chen, Richard M. Hoar, Narsingh D. Agnish, Paul J. Benke, John T. Braun, Cynthia J. Curry, Paul M. Fernhoff, Art W. Grix, Ira T. Lott, James M. Richard, Shyan C. Sun
Publikováno v:
New England Journal of Medicine. 313:837-841
Retinoic acid, an analogue of vitamin A, is known to be teratogenic in laboratory animals and has recently been implicated in a few clinical case reports. To study the human teratogenicity of this agent, we investigated 154 human pregnancies with fet
Publikováno v:
Teratology. 17:37-41
The augmentation of methotrexate-induced embryotoxicity by aspirin was studied. Pregnant Charles River CD rats were given methotrexate or aspirin alone or in combination on gestation day 9 or 12. The frequency of fetal abnormalities was not affected