Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Richard M. Gilley"'
Autor:
Richard M. Gilley, Suzanne M. Michalek, Jonathan F. Smith, George V. Ludwig, John H. Eldridge, Terrence E. Greenway, Jay K. Staas
Publikováno v:
Vaccine. 16:1314-1323
Venezuelan equine encephalomyelitis (VEE) virus, a member of the family Togaviridae, genus Alphavirus, causes disease in humans and equids. The virus is normally transmitted by the bite of an infected mosquito however, it can also be highly infectiou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f067e66aa52523dc0148d859d76284
https://doi.org/10.1016/s0264-410x(98)00008-5
https://doi.org/10.1016/s0264-410x(98)00008-5
Autor:
RAYMOND J. JACKSON, HERMAN F. STAATS, JIANGCHUN XU-AMANO, ICHIRO TAKAHASHI, HIROSHI KIYONO, MICHAEL E. HUDSON, RICHARD M. GILLEY, STEVEN N. CHATFIELD, JERRY R. McGHEE
Publikováno v:
Annals of the New York Academy of Sciences. 731:217-225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a652d0bf16e58296620a92829b6dbb3
https://doi.org/10.1111/j.1749-6632.1994.tb00011.x
https://doi.org/10.1111/j.1749-6632.1994.tb00011.x
Autor:
Richard W. Compans, Wen-Qiang Huang, Richard M. Gilley, Dennis P. Schafer, Jay K. Staas, Miroslav J. Novak, Zina Moldoveanu, Jiri Mestecky
Publikováno v:
Journal of Controlled Release. 28:131-141
Mucosal membranes are the most frequent portals of entry of almost all infectious agents. The most important protective humoral factors on mucosal surfaces are locally produced antibodies predominantly of the IgA isotype. Therefore, the induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96cc63e09131ed3b9d4b247d51f798f6
https://doi.org/10.1016/0168-3659(94)90160-0
https://doi.org/10.1016/0168-3659(94)90160-0
Autor:
Dennis P. Schafer, Richard M. Gilley, Richard W. Compans, Jay K. Staas, Wen-Qiang Huang, Zina Moldoveanu, Jiri Mestecky, Miroslav J. Novak
Publikováno v:
Journal of Infectious Diseases. 167:84-90
Polymeric microspheres were evaluated as an oral antigen delivery system for immunization with influenza virus. The immune responses obtained were compared after either oral or systemic immunization of BALB/c mice using purified, formalin-inactivated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3373063f6447c7652684f2add6fad9f
https://doi.org/10.1093/infdis/167.1.84
https://doi.org/10.1093/infdis/167.1.84
Autor:
Jay K. Staas, J A Meulbroek, Thomas R. Tice, Richard M. Gilley, Jerry R. McGhee, John H. Eldridge
Publikováno v:
Molecular Immunology. 28:287-294
The utility of biodegradable and biocompatible microspheres as a vaccine delivery system for the induction of systemic and disseminated mucosal antibody responses was investigated. Intraperitoneal (ip) injection into mice of 1-10 microns microspheres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa2c2c057cf7ef16a6f607d9ddfd293
https://doi.org/10.1016/0161-5890(91)90076-v
https://doi.org/10.1016/0161-5890(91)90076-v
Autor:
Richard M. Gilley, Maninder S. Hora, Rajsharan K. Rana, Jack H. Nunberg, Michael E. Hudson, Thomas Robert Tice
Publikováno v:
Nature Biotechnology. 8:755-758
We have evaluated the use of biodegradable poly(DL-lactide-co-glycolide) microspheres for the controlled release of interleukin-2 (IL-2) and its modified forms: succinyl IL-2 (SIL-2) and polyethylene glycol-modified IL-2 (PEG IL-2). We show that a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74bd18cc04ab5d6f7b96cf3aabee54c
https://doi.org/10.1038/nbt0890-755
https://doi.org/10.1038/nbt0890-755
Autor:
Richard M. Gilley, Michael E. Hudson, Thomas R. Tice, Maninder S. Hora, Rajsharan K. Rana, Jack H. Nunberg
Publikováno v:
Pharmaceutical Research. :1190-1194
Human serum albumin (HSA) was encapsulated in a 50:50 copolymer of DL-lactide/glycolide in the form of microspheres. These microspheres were used as a model formulation to study the feasibility of controlling the release of large proteins over a 20-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f8624da7858bef6f1833d8f4d6856f
https://doi.org/10.1023/a:1015948829632
https://doi.org/10.1023/a:1015948829632
Autor:
J A Meulbroek, Thomas R. Tice, Charlotte J. Hammond, Jay K. Staas, Richard M. Gilley, John H. Eldridge
Publikováno v:
Journal of Controlled Release. 11:205-214
Microspheres prepared from various polymers were evaluated for their usefulness as carriers for the targeted delivery of vaccine antigens to the gut-associated lymphoid tissues. Following oral administration to mice, microspheres consisting of polyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbfd7a20b1f46742a1a935422f5b2c42
https://doi.org/10.1016/0168-3659(90)90133-e
https://doi.org/10.1016/0168-3659(90)90133-e
Autor:
Eric M. Mishkin, Preston A. Marx, Jay K. Staas, Agegnehu Gettie, Zimra R. Israel, David C. Montefiori, John H. Eldridge, Richard M. Gilley, Sally T. Ishizaka
Publikováno v:
AIDS research and human retroviruses. 15(12)
We determined the efficacy of immunization with microsphere-encapsulated whole inactivated simian immunodeficiency virus (SIV) by combined systemic and mucosal administration to protect female rhesus macaques against vaginal challenge with homologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8aed4f3155457655392f3b0339e09c
https://pubmed.ncbi.nlm.nih.gov/10461832
https://pubmed.ncbi.nlm.nih.gov/10461832
Autor:
Sally T. Ishizaka, John H. Eldridge, Agegnehu Gettie, Peter J. Dailey, David C. Montefiori, Zimra R. Israel, Jay K. Staas, Preston A. Marx, Eric M. Mishkin, Richard M. Gilley
Publikováno v:
Vaccine. 17(22)
Male rhesus macaques were immunized mucosally with microsphere-encapsulated formalin-inactivated simian immunodeficiency virus (SIV) particles in a test of immunogenicity and protection against mucosal SIV challenge. Tracheal boosting of animals that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c913d2821d28589dd6396bbda7f5c59
https://pubmed.ncbi.nlm.nih.gov/10438051
https://pubmed.ncbi.nlm.nih.gov/10438051