Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Richard M. Badge"'
Autor:
Raheleh Rahbari, Tom Sheahan, Vasileios Modes, Pam Collier, Catriona Macfarlane, Richard M. Badge
Publikováno v:
BioTechniques, Vol 46, Iss 4, Pp 277-284 (2009)
The HeLa cell line is the oldest, most widely distributed, permanent human cell line. As a nearly ubiquitous inhabitant of laboratories using tissue culture techniques, its aggressive growth characteristics make it a problematic contaminant that can
Externí odkaz:
https://doaj.org/article/e2039904de1143a9a46ea6a916892760
Autor:
Lauren Lansdowne, Matyas Liptovszky, Kristiana Brink, Katie Dripps, Vivienne Li, Edward J. Hollox, Richard M. Badge
Publikováno v:
Gibbon Conservation in the Anthropocene ISBN: 9781108785402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9865436066dc11c8633f4dd94050d4
https://doi.org/10.1017/9781108785402.020
https://doi.org/10.1017/9781108785402.020
Autor:
Peter N. Robinson, Marek Figlerowicz, Stefan Mundlos, Marten Jäger, Richard M. Badge, Tobias Penzkofer, Tomasz Zemojtel
Publikováno v:
Nucleic Acids Research
LINE-1 (L1) insertions comprise as much as 17% of the human genome sequence, and similar proportions have been recorded for other mammalian species. Given the established role of L1 retrotransposons in shaping mammalian genomes, it becomes an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1ed7675d7a4970bd43014f444ca96b
http://europepmc.org/articles/PMC5210629
http://europepmc.org/articles/PMC5210629
Autor:
Cristina Tufarelli, Richard M. Badge
Publikováno v:
Human Retrotransposons in Health and Disease ISBN: 9783319483436
Retrotransposition, the ability of retrotransposons to move to different locations within the genome via an RNA intermediate, has been for many years at the forefront of research into the role of these elements in cancer. Indeed, it is intuitive to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6d360989f210866d3dcbfecbf61e81
https://doi.org/10.1007/978-3-319-48344-3_11
https://doi.org/10.1007/978-3-319-48344-3_11
Autor:
Raheleh, Rahbari, Richard M, Badge
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1400
With the advent of new generations of high-throughput sequencing technologies, the catalog of human genome variants created by retrotransposon activity is expanding rapidly. However, despite these advances in describing L1 diversity and the fact that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c782327eb0876137ba6739158eacb73
https://pubmed.ncbi.nlm.nih.gov/26895048
https://pubmed.ncbi.nlm.nih.gov/26895048
Autor:
Richard M. Badge, Raheleh Rahbari
Publikováno v:
Methods in Molecular Biology ISBN: 9781493933709
With the advent of new generations of high-throughput sequencing technologies, the catalog of human genome variants created by retrotransposon activity is expanding rapidly. However, despite these advances in describing L1 diversity and the fact that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ee09bf36eddbee8e655dd593f455b7
https://doi.org/10.1007/978-1-4939-3372-3_6
https://doi.org/10.1007/978-1-4939-3372-3_6
Publikováno v:
Annual Review of Genomics and Human Genetics. 12:187-215
The completion of the human genome reference sequence ushered in a new era for the study and discovery of human transposable elements. It now is undeniable that transposable elements, historically dismissed as junk DNA, have had an instrumental role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f79ed441a6101bafd5b7e2589c2294
https://doi.org/10.1146/annurev-genom-082509-141802
https://doi.org/10.1146/annurev-genom-082509-141802
Publikováno v:
Freeman, P, Macfarlane, C, Collier, P, Jeffreys, A J & Badge, R M 2011, ' L1 Hybridization Enrichment : A Method for Directly Accessing De Novo L1 Insertions in the Human Germline ', Human Mutation, vol. 32, no. 8, pp. 978-988 . https://doi.org/10.1002/humu.21533
Human Mutation
Human Mutation
Long interspersed nuclear element 1 (L1) retrotransposons are the only autonomously mobile human transposable elements. L1 retrotransposition has shaped our genome via insertional mutagenesis, sequence transduction, pseudogene formation, and ectopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61bc1d8443bf528447019075b336a21
https://doi.org/10.1002/humu.21533
https://doi.org/10.1002/humu.21533
Autor:
Angela Macia, Marta García-Cañadas, Martin Muñoz-Lopez, Jose L. Garcia-Perez, Richard M. Badge
Publikováno v:
Mobile Genetic Elements. 1:122-127
The ongoing activity of the human retrotransposon Long Interspersed Element 1 (LINE-1 or L1) continues to impact the human genome in various ways. Throughout evolution, mammalian and primate genomes have been under selection to generate strategies to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9a441ef350ee78345b8c95f5d19f37
https://doi.org/10.4161/mge.1.2.16730
https://doi.org/10.4161/mge.1.2.16730
Autor:
Santiago Morell, Angela Macia, José Luis Cortés, Robert K. Hastings, Juan A. Marchal, Jose L. Garcia-Perez, Gema Lucena-Aguilar, Martin Muñoz-Lopez, Richard M. Badge
Publikováno v:
Molecular and Cellular Biology. 31:300-316
Long interspersed element 1s (LINE-1s or L1s) are a family of non-long-terminal-repeat retrotransposons that predominate in the human genome. Active LINE-1 elements encode proteins required for their mobilization. L1-encoded proteins also act in tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3775a5708c7cf8adec4284aef75e36c6
https://doi.org/10.1128/mcb.00561-10
https://doi.org/10.1128/mcb.00561-10