Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Richard M Rossoll"'
Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts.
Autor:
Zheng Shen, John V Fahey, Jack E Bodwell, Marta Rodriguez-Garcia, Richard M Rossoll, Sarah G Crist, Mickey V Patel, Charles R Wira
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69854 (2013)
The use of topical and oral adenosine derivatives in HIV prevention that need to be maintained in tissues and cells at effective levels to prevent transmission prompted us to ask whether estradiol could influence the regulation of catabolic nucleotid
Externí odkaz:
https://doaj.org/article/d68a385c19bd45718b5c61300c4b24ac
PROBLEM: The contribution of fibroblasts to innate immune protection of the human female reproductive tract (FRT) against viral pathogens is relatively unknown. METHOD OF STUDY: Endometrial (EM), endocervical (Cx), and ectocervical (ECx) fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4eb5517d26da2d3377b41825d01f04c
https://europepmc.org/articles/PMC6275105/
https://europepmc.org/articles/PMC6275105/
Interleukin (IL)-27 is a pleiotropic cytokine that regulates multiple aspects of innate and adaptive immunity, but whose role in immune protection of the female reproductive tract is unknown. Although not constitutively expressed by human uterine epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80424498c5b54f48fb9f48852dbeb658
https://europepmc.org/articles/PMC5867512/
https://europepmc.org/articles/PMC5867512/
Autor:
Mickey V. Patel, Richard M. Rossoll, Marta Rodriguez-Garcia, Jack E. Bodwell, Charles R. Wira, Zheng Shen
Publikováno v:
Scientific Reports
Disruption of the epithelium in the female reproductive tract (FRT) is hypothesized to increase HIV infection risk by interfering with barrier protection and facilitating HIV-target cell recruitment. Here we determined whether Tenofovir (TFV), used v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8197272f3894acf17059dd2af1fbbd83
http://europepmc.org/articles/PMC5377941
http://europepmc.org/articles/PMC5377941
Publikováno v:
Immunology. 135:51-62
Summary Cells of the female reproductive tract (FRT) can present antigen to naive and memory T cells. However, the effects of oestrogen, known to modulate immune responses, on antigen presentation in the FRT remain undefined. In the present study, DO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d370d9ebd13b745c08157f0fc725dae7
https://doi.org/10.1111/j.1365-2567.2011.03512.x
https://doi.org/10.1111/j.1365-2567.2011.03512.x
Autor:
Richard M. Rossoll, Kimberly D. Coleman, Charles R. Wira, John V. Fahey, Jacqueline A. Wright, Sarah G. Crist, Mimi Ghosh
Publikováno v:
American Journal of Reproductive Immunology. 67:44-53
Citation Coleman KD, Ghosh M, Crist SG, Wright JA, Rossoll RM, Wira CR, Fahey JV. Modulation of Hepatocyte Growth Factor secretion in human female reproductive tract stromal fibroblasts by poly (I:C) and estradiol. Am J Reprod Immunol 2012; 67: 44–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cea9843d88a647d4e0c2e5cd99b54de1
https://doi.org/10.1111/j.1600-0897.2011.01063.x
https://doi.org/10.1111/j.1600-0897.2011.01063.x
Publikováno v:
The Journal of Immunology. 175:1795-1804
To study Ag presentation in the female reproductive tract, DO11.10 TCR transgenic mice specific for the class II MHC-restricted OVA323–339 peptide and nontransgenic BALB/c mice were used. We report here that freshly isolated uterine epithelial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56873ee6890a99225d6f8ff3978b83dc
https://doi.org/10.4049/jimmunol.175.3.1795
https://doi.org/10.4049/jimmunol.175.3.1795
Autor:
Charles R. Wira, Richard M. Rossoll
Publikováno v:
Immunology. 109:398-406
We have previously shown that oestradiol treatment of ovariectomized rats for 3 days inhibits antigen presentation by uterine stromal cells at a time when oestradiol increases the numbers of antigen-presenting cells (APC) in the uterine stroma. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f521b8e1d0795331283cef8969436
https://doi.org/10.1046/j.1365-2567.2003.01670.x
https://doi.org/10.1046/j.1365-2567.2003.01670.x
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 84:79-87
The objective of this study was to determine whether thymus cells present antigen and if endocrine balance influences antigen presentation. We report here that antigen presenting cells (APC) from the thymus glands of male and female rats, when incuba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f377e4e2ccb1cd3219f76d24270542c1
https://doi.org/10.1016/s0960-0760(03)00002-5
https://doi.org/10.1016/s0960-0760(03)00002-5
Publikováno v:
Endocrinology. 143:2872-2879
Estradiol is known to inhibit antigen presentation in the vagina. We report here that TGFbeta mediates the action of estradiol on vaginal antigen presenting cells (APC). When vaginal APC from ovariectomized rats were incubated with increasing concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf14c0b748a0e47c88dc04a1594e43c9
https://doi.org/10.1210/endo.143.8.8938
https://doi.org/10.1210/endo.143.8.8938