Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Richard M Kinney"'
Autor:
Elizabeth A Dietrich, Stanley A Langevin, Claire Y-H Huang, Payal D Maharaj, Mark J Delorey, Richard A Bowen, Richard M Kinney, Aaron C Brault
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004938 (2016)
West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian spec
Externí odkaz:
https://doaj.org/article/763bbd6c9ec745b2b45fd8630a2f4df5
Autor:
Claire Y-H Huang, Richard M Kinney, Jill A Livengood, Bethany Bolling, John J Arguello, Betty E Luy, Shawn J Silengo, Karen L Boroughs, Janae L Stovall, Akundi P Kalanidhi, Aaron C Brault, Jorge E Osorio, Dan T Stinchcomb
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2243 (2013)
We have developed a manufacturing strategy that can improve the safety and genetic stability of recombinant live-attenuated chimeric dengue vaccine (DENVax) viruses. These viruses, containing the pre-membrane (prM) and envelope (E) genes of dengue se
Externí odkaz:
https://doaj.org/article/f4fd186079c94a3b8c24a3a99d2d23a7
Autor:
Stanley A. Langevin, Payal D. Maharaj, Aaron C. Brault, Richard A. Bowen, Claire Y.-H. Huang, Richard M. Kinney, Elizabeth A. Dietrich, Mark J. Delorey
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004938 (2016)
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004938 (2016)
West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a8197949b13ab2cf22340a84d35a59
http://europepmc.org/articles/PMC4993437
http://europepmc.org/articles/PMC4993437
Autor:
Tim D. Powell, Charalambos D. Partidos, Shawn J. Silengo, Richard M. Kinney, John J. Arguello, Claire Y.-H. Huang, Joseph N. Brewoo, Dan T. Stinchcomb, Jorge E. Osorio
Publikováno v:
Vaccine. 30:1513-1520
Formulations of chimeric dengue vaccine (DENVax) viruses containing the pre-membrane (prM) and envelope (E) genes of serotypes 1–4 expressed in the context of the attenuated DENV-2 PDK-53 genome were tested for safety, immunogenicity and efficacy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1801d6c3f83b7cd66119dcc0d1a108c2
https://doi.org/10.1016/j.vaccine.2011.11.072
https://doi.org/10.1016/j.vaccine.2011.11.072
Autor:
Tom Solomon, Li Li, Alan D.T. Barrett, Kyung Min Chung, Melissa C. Whiteman, Jason A. Wicker, Claire Y.-H. Huang, David W.C. Beasley, Michael S. Diamond, Richard M. Kinney
Publikováno v:
Vaccine. 28:1075-1083
West Nile virus is an arthropod-borne flavivirus that has caused substantial morbidity and mortality to animals as well as humans since its introduction in to the New York area in 1999. Given that there are no antiviral drugs available for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b32d637e6e23478f5c32b1c8ee5972
https://doi.org/10.1016/j.vaccine.2009.10.112
https://doi.org/10.1016/j.vaccine.2009.10.112
Autor:
Siritorn Butrapet, John T. Roehrig, Kelly J. Moss, Claire Y.-H. Huang, Shawn J. Silengo, Thomas Childers, Richard M. Kinney, Steven M. Erb, Amanda E. Calvert, Carol D. Blair
Publikováno v:
Virology. 396:305-315
The flaviviral envelope (E) protein directs virus-mediated membrane fusion. To investigate membrane fusion as a requirement for virus growth, we introduced 27 unique mutations into the fusion peptide of an infectious cDNA clone of dengue 2 virus and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b410883c31e9b4f62aa37e3dfaa07d
https://doi.org/10.1016/j.virol.2009.10.027
https://doi.org/10.1016/j.virol.2009.10.027
Autor:
Stacy Crumley, Claire Y.-H. Huang, Shawn J. Silengo, Patrick L. Iversen, Robert E. Blouch, Adams Amantana, David A. Stein, Richard M. Kinney
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: To determine the antiviral activity of phosphorodiamidate morpholino oligomers (PMO) and peptide-conjugated PMO (PPMO) in AG129 mice infected with dengue 2 virus (DENV-2). Methods: Antisense PMO and PPMO were designed against the 5 0 term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d25e12821b0f21e6281bf3bc1d610
http://europepmc.org/articles/PMC7109848
http://europepmc.org/articles/PMC7109848
Autor:
Barry R. Miller, Richard M. Kinney, Aaron C. Brault, Wanichaya N. Ramey, Claire Y.-H. Huang, Nicholas A. Panella, Ann M. Powers, Stanley A. Langevin, Richard A. Bowen, Edward C. Holmes
Publikováno v:
Nature Genetics. 39:1162-1166
West Nile virus (WNV), first recognized in North America in 1999, has been responsible for the largest arboviral epiornitic and epidemic of human encephalitis in recorded history. Despite the well-described epidemiological patterns of WNV in North Am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1085cb380a3cf96ca51b766cdbb939
https://doi.org/10.1038/ng2097
https://doi.org/10.1038/ng2097
Publikováno v:
Journal of General Virology. 88:1748-1752
A C57U nucleotide mutation in a predicted RNA stem structure (nt 11–16/56–61) of the 5′ non-coding region (5′NCR) of dengue 2 (DEN-2) 16681 virus is partially attenuating, but unstable during serial passage of certain candidate DEN-2 PDK-53-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcb8370a7778f764b6b0555b7876975
https://doi.org/10.1099/vir.0.82455-0
https://doi.org/10.1099/vir.0.82455-0
Autor:
Melissa C. Whiteman, Jason A. Wicker, Shuliu Zhang, Richard M. Kinney, Stephen Higgs, Alan D.T. Barrett, David W.C. Beasley, C. Todd Davis, Bradley S. Schneider
Publikováno v:
Virology. 349:245-253
West Nile virus (WNV) NS4B is a small hydrophobic nonstructural protein that is hypothesized to participate both in viral replication and evasion of host innate immune defenses. The protein has four cysteine residues (residues 102, 120, 227, and 237)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd7e11ea7eeda60fb9cd039d827aa5f
https://doi.org/10.1016/j.virol.2006.03.007
https://doi.org/10.1016/j.virol.2006.03.007