Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Richard M Keating"'
Autor:
Michael H Weisman, Joachim H Ix, Jill M Norris, James R ODell, Ted R Mikuls, Kevin D Deane, V Michael Holers, M Kristen Demoruelle, Jane H Buckner, Richard M Keating, Jan M Hughes-Austin, Samuel R Ward
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/68b99268068c45e2b8c320a8ce953a44
Autor:
Lauren A. Vanderlinden, Elizabeth A. Bemis, Jennifer Seifert, Joel M. Guthridge, Kendra A. Young, Mary Kristen Demoruelle, Marie Feser, Wade DeJager, Susan Macwana, Ted R. Mikuls, James R. O’Dell, Michael H. Weisman, Jane Buckner, Richard M. Keating, Patrick M. Gaffney, Jennifer A. Kelly, Carl D. Langefeld, Kevin D. Deane, Judith A. James, Vernon Michael Holers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveHigher 25-hydroxyvitamin D (25(OH)D) levels have been associated with reduced risk for autoimmune diseases and are influenced by vitamin D metabolism genes. We estimated genetically-determined vitamin D levels by calculating a genetic risk s
Externí odkaz:
https://doaj.org/article/8ead74bae78b4210a2dbb92be12d3596
Autor:
Jennifer A. Seifert, Elizabeth A. Bemis, Kristina Ramsden, Cassidy Lowell, Kristen Polinski, Marie Feser, Chelsie Fleischer, M. Kristen Demoruelle, Jane Buckner, Peter K. Gregersen, Richard M. Keating, Ted R. Mikuls, James R. O'Dell, Michael H. Weisman, Kevin D. Deane, Jill M. Norris, Allen C. Steere, V. Michael Holers
Publikováno v:
Arthritis & Rheumatology. 75:507-516
Autor:
Marcy B. Bolster, Darren Tabechian, Bethany Marston, Edwin A. Smith, Ellen Goldmuntz, Richard M. Keating, Lynette Keyes-Elstein, Jeffrey R. Curtis, Andreea Coca, Karen D. Boyle, Nida Meednu, Jennifer H. Anolik, Jennifer Barnard, Ralf G. Thiele, Jonathan Graf, Beverly Welch, Meggan Mackay, Kelly Callahan
Publikováno v:
Arthritis & Rheumatology. 74:200-211
Objective B cells can become activated in germinal center (GC) reactions in secondary lymphoid tissue and ectopic GCs in synovium in RA that may be TNF and lymphotoxin (LT) dependent. Here we characterized the peripheral B cell compartment longitudin
Autor:
Jennifer A, Seifert, Elizabeth A, Bemis, Kristina, Ramsden, Cassidy, Lowell, Kristen, Polinski, Marie, Feser, Chelsie, Fleischer, M Kristen, Demoruelle, Jane, Buckner, Peter K, Gregersen, Richard M, Keating, Ted R, Mikuls, James R, O'Dell, Michael H, Weisman, Kevin D, Deane, Jill M, Norris, Allen C, Steere, V Michael, Holers
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Prevotella copri (Pc), a gut commensal, has been reported to be an immune relevant organism in individuals with rheumatoid arthritis (RA). Our goal was to evaluate anti-Pc antibody responses in our participant cohorts and determine when in the natura
Autor:
Jill M. Norris, Marie L. Feser, Kevin D. Deane, V. Michael Holers, Fan Yang, Michael H. Weisman, M. Kristen Demoruelle, Peter K. Gregersen, Tessa L. Crume, Ted R. Mikuls, Jane H. Buckner, Elizabeth A. Bemis, Jennifer Seifert, Kristen J. Polinski, Richard M. Keating, Michael J. Clare-Salzler, James R. O'Dell, Nichole Reisdorph
Publikováno v:
Arthritis Rheumatol
OBJECTIVE To determine the association of polyunsaturated fatty acid (PUFA)-derived lipid mediators with progression from rheumatoid arthritis (RA)-related autoimmunity to inflammatory arthritis (IA). METHODS We conducted a prospective cohort study u
Autor:
James R. O'Dell, Christopher C. Striebich, Stacey Brake, Perry M. Nicassio, Kevin D. Deane, V. Michael Holers, Jill M. Norris, Jennifer Seifert, Peter K. Gregersen, Jane H. Buckner, Elizabeth A. Bemis, Michael H. Weisman, Richard M. Keating, M. Kristen Demoruelle, Marie L. Feser, Ted R. Mikuls, Kristen J. Polinski
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE The aim of this study was to determine the association of perceived stress with incident inflammatory arthritis (IA) defined as having at least 1 joint consistent with rheumatoid arthritis (RA)-like synovitis based on examination. METHODS W
Autor:
Ellen Goldmuntz, Beverly Welch, Jane Box, Meagan Spychala, Sherrie Callahan, Mary Chester Wasko, Alan Kivitz, Maria Dall'Era, Cynthia Aranow, Karen D. Boyle, Tracy M. Frech, Meggan Mackay, Marcy B. Bolster, Richard M. Keating, Christopher C. Striebich, Betty Diamond, Weiquang Huang, Kate York, John J. Cush, Anne Davidson, William St. Clair, Lynette Keyes-Elstein, Peta-Gay Ricketts, Ewa Olech
Publikováno v:
Rheumatology (Oxford)
Objectives 3-hydroxy-3-methylglutaryl coenzyme-A (HMG Co-A) reductase inhibitors (statins) are standard treatment for hyperlipidaemia. In addition to lipid-lowering abilities, statins exhibit multiple anti-inflammatory effects. The objectives of this
Autor:
V. Michael Holers, James R. O’Dell, Ashley Visser, Sonia Khatter, Kristen J. Polinski, Michael Mahler, Jill M. Norris, Ted R. Mikuls, Kevin D. Deane, Michael H. Weisman, M. Kristen Demoruelle, Heather M. Berens, Justin August, Jane H. Buckner, Richard M. Keating, Peter K. Gregersen
Publikováno v:
J Rheumatol
Objective.We investigated the association of age and anticyclic citrullinated peptide antibodies (anti-CCP) in subjects without rheumatoid arthritis (RA).Methods.Serum was tested for anti-CCP3.1 (IgG/IgA) in 678 first-degree relatives (FDR) of patien
Autor:
Marie L. Feser, William H. Robinson, Kevin D. Deane, Richard M. Keating, Rebecka L. Bourn, Hua Chen, James R. O'Dell, Patrick M. Gaffney, Michael H. Weisman, M. Kristen Demoruelle, Jennifer Seifert, Jill M. Norris, David A. Hafler, John B. Harley, Carl D. Langefeld, Jane H. Buckner, Elizabeth A. Bemis, Judith A. James, Kevin C. O’Connor, V. Michael Holers, Jennifer A. Kelly, Joel M. Guthridge, Kendra A. Young
Publikováno v:
EBioMedicine. 42:76-85
Background Autoimmune disease prevention requires tools to assess an individual's risk of developing a specific disease. One tool is disease-associated autoantibodies, which accumulate in an asymptomatic preclinical period. However, patients sometime