Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Richard M Gronostajski"'
Autor:
Elizaveta V Bashkirova, Nell Klimpert, Kevin Monahan, Christine E Campbell, Jason Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Beka Stecky, Gilad Barnea, Xiaoliang Sunney Xie, Ishmail Abdus-Saboor, Benjamin M Shykind, Bianca J Marlin, Richard M Gronostajski, Alexander Fleischmann, Stavros Lomvardas
Publikováno v:
eLife, Vol 12 (2023)
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in the mouse genome in a probabilistic, yet stereotypic fashion. Here, we propose that top
Externí odkaz:
https://doaj.org/article/e923cd877d264e7291581c56826388d1
Autor:
Caitríona O'Connor, Joana Campos, Jason M Osinski, Richard M Gronostajski, Alison M Michie, Karen Keeshan
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120102 (2015)
The commitment of stem and progenitor cells toward specific hematopoietic lineages is tightly controlled by a number of transcription factors that regulate differentiation programs via the expression of lineage restricting genes. Nuclear factor one (
Externí odkaz:
https://doaj.org/article/7b3c6395e167472f9b6ae493eb3d4077
Autor:
Lachlan Harris, Chantelle Dixon, Kathleen Cato, Yee Hsieh Evelyn Heng, Nyoman D Kurniawan, Jeremy F P Ullmann, Andrew L Janke, Richard M Gronostajski, Linda J Richards, Thomas H J Burne, Michael Piper
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65478 (2013)
Identification of the genes that regulate the development and subsequent functioning of the hippocampus is pivotal to understanding the role of this cortical structure in learning and memory. One group of genes that has been shown to be critical for
Externí odkaz:
https://doaj.org/article/bbb266f2644f4dfa9fad067df7de0b08
Autor:
Dong-Seol Lee, Won-Joon Yoon, Eui Sic Cho, Heung-Joong Kim, Richard M Gronostajski, Moon-Il Cho, Joo-Cheol Park
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29160 (2011)
Transforming growth factor-β1 (TGF-β1) signaling plays a key role in vertebrate development, homeostasis, and disease. Nuclear factor I-C (NFI-C) has been implicated in TGF-β1 signaling, extracellular matrix gene transcription, and tooth root deve
Externí odkaz:
https://doaj.org/article/bb1fcf4c71de4841943e95bd36677cfa
Autor:
Weining Lu, Fabiola Quintero-Rivera, Yanli Fan, Fowzan S Alkuraya, Diana J Donovan, Qiongchao Xi, Annick Turbe-Doan, Qing-Gang Li, Craig G Campbell, Alan L Shanske, Elliott H Sherr, Ayesha Ahmad, Roxana Peters, Benedict Rilliet, Paloma Parvex, Alexander G Bassuk, David J Harris, Heather Ferguson, Chantal Kelly, Christopher A Walsh, Richard M Gronostajski, Koenraad Devriendt, Anne Higgins, Azra H Ligon, Bradley J Quade, Cynthia C Morton, James F Gusella, Richard L Maas
Publikováno v:
PLoS Genetics, Vol 3, Iss 5, p e80 (2007)
Complex central nervous system (CNS) malformations frequently coexist with other developmental abnormalities, but whether the associated defects share a common genetic basis is often unclear. We describe five individuals who share phenotypically rela
Externí odkaz:
https://doaj.org/article/ddf5c0ea2cd942388b69b1b924bd0135
Autor:
Elise Matuzelski, Alexandra Essebier, Lachlan Harris, Richard M. Gronostajski, Tracey J. Harvey, Michael Piper
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-3 (2020)
Abstract Objective Nuclear Factor One X (NFIX) is a transcription factor expressed by neural stem cells within the developing mouse brain and spinal cord. In order to characterise the pathways by which NFIX may regulate neural stem cell biology withi
Externí odkaz:
https://doaj.org/article/a0ce9aefc2004715a118f6a8f2a8406f
Autor:
Oressia Zalucki, Danyon Harkins, Lachlan Harris, Thomas H. J. Burne, Richard M. Gronostajski, Michael Piper
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective The active place avoidance task (APA) is a behavioural task used to assess learning and memory in rodents. This task relies on the hippocampus, a region of the cerebral cortex capable of generating new neurons from neural stem cell
Externí odkaz:
https://doaj.org/article/67b9fc24f04440d99e9584e97e3ba863
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 2-9 (2017)
Emerging evidence indicates that nuclear factor I/B (NFIB), a transcription factor required for proper development and regulation of cellular differentiation in several tissues, also plays critical roles in cancer. Despite being a metastatic driver i
Externí odkaz:
https://doaj.org/article/e753114b623845f8b3e006cb88a1dab3
Autor:
Elizaveta V. Bashkirova, Nell Klimpert, Ariel Pourmorady, Kevin Monahan, Christine E. Campbell, Jason M. Osinski, Longzhi Tan, Ira Schieren, Beka Stecky, Gilad Barnea, X. Sunney Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones Marlin, Richard M. Gronostajski, Alexander Fleischmann, Stavros Lomvardas
Publikováno v:
bioRxiv
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in a probabilistic, yet stereotypic fashion. Here, we show that topographic restrictions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442d805e4a48d07128c580ad2a789888
https://europepmc.org/articles/PMC10055043/
https://europepmc.org/articles/PMC10055043/
Autor:
Raul Ayala Davila, Cassy Spiller, Danyon Harkins, Tracey Harvey, Philip W Jordan, Richard M Gronostajski, Michael Piper, Josephine Bowles
Publikováno v:
Biology of Reproduction. 106:1191-1205
Members of the nuclear factor I (NFI) family are key regulators of stem cell biology during development, with well-documented roles for NFIA, NFIB, and NFIX in a variety of developing tissues, including brain, muscle, and lung. Given the central role