Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Richard M, Spencer"'
Publikováno v:
Curr Opin Toxicol
New approach methodologies (NAMs) refer to any non-animal technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment that avoids the use of intact animals. A spectrum of in
Publikováno v:
Current Opinion in Toxicology. :119-126
New approach methodologies (NAMs) refer to any non-animal technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment that avoids the use of intact animals. A spectrum of in
Autor:
Menghang Xia, Robert G. Ellis-Hutchings, Jill A Franzosa, Nancy C. Baker, Edward W. Carney, Todd J. Zurlinden, Raja S. Settivari, Thomas B. Knudsen, Richard M. Spencer, Katerine S. Saili, Nicole Kleinstreuer, Shuaizhang Li
Publikováno v:
Curr Opin Toxicol
The more than 80,000 chemicals in commerce present a challenge for hazard assessments that toxicity testing in the 21(st) century strives to address through high-throughput screening (HTS) assays. Assessing chemical effects on human development adds
Publikováno v:
Chemical Research in Toxicology. 30:965-979
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from chemical-induced cellular alterations, we built a multi-cellular agent-based model in Compu
Autor:
Richard M. Spencer, M. Shane Hutson, Ashley W. Seifert, Maxwell C.K. Leung, Thomas B. Knudsen
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 64
Hypospadias is a developmental defect of urethral tube closure that has a complex etiology involving genetic and environmental factors, including anti-androgenic and estrogenic disrupting chemicals; however, little is known about the morphoregulatory
Autor:
Richard M. Spencer, Luis A. Quevedo, Ian R. Gendall, Richard H. Sillitoe, Carlos O. Puente, Juan P. León, Romulo R. P Vedo
Publikováno v:
SEG Discovery. :1-15
Grassroots exploration has led to discovery of 10 porphyry copper prospects in the previously unexplored Jurassic arc of southeastern Ecuador. The prospects are located in steep, wet, jungle-covered terrain in the Pangui area, part of the Cordillera
Autor:
Michael R. Rountree, David J. Dix, Richard M. Spencer, Nisha S. Sipes, Thomas B. Knudsen, Nancy C. Baker, Nicole Kleinstreuer, David M. Reif
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 4, p e1002996 (2013)
PLoS Computational Biology
PLoS Computational Biology
Vascular development is a complex process regulated by dynamic biological networks that vary in topology and state across different tissues and developmental stages. Signals regulating de novo blood vessel formation (vasculogenesis) and remodeling (a
Autor:
Ann M. Richard, Keith A. Houck, Fathi Elloumi, Matthew T. Martin, Richard S. Judson, Richard M. Spencer, Maritja Wolf, David J. Dix, Tommy Cathey, Thomas R. Transue
Publikováno v:
Toxicology and applied pharmacology. 233(1)
ACToR (Aggregated Computational Toxicology Resource) is a database and set of software applications that bring into one central location many types and sources of data on environmental chemicals. Currently, the ACToR chemical database contains inform
Publikováno v:
Computers in biology and medicine. 31(6)
Knowledge of human lung morphology is a subject critical to many areas of medicine. The visualization of lung structures naturally lends itself to computer graphics modeling due to the large number of airways involved and the complexities of the bran
Autor:
Nancy C. Baker, Richard M. Spencer, Michael R. Rountree, Tamara Tal, Nisha S. Sipes, Nicole Kleinstreuer, Thomas B. Knudsen, Kelly J. Chandler, Stephanie Padilla, E. Sidney Hunter
Publikováno v:
Reproductive Toxicology. 34:148