Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Richard M, Mangano"'
Autor:
Maurizio Fava, Stephen Stahl, Luca Pani, Sara De Martin, Marco Pappagallo, Clotilde Guidetti, Andrea Alimonti, Ezio Bettini, Richard M. Mangano, Thomas Wessel, Marc de Somer, Judy Caron, Ottavio V. Vitolo, Gina R. DiGuglielmo, Adam Gilbert, Hiren Mehta, Morgan Kearney, Andrea Mattarei, Marco Gentilucci, Franco Folli, Sergio Traversa, Charles E. Inturrisi, Paolo L. Manfredi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a521b8ae328a89b18e52662a6765c
http://hdl.handle.net/11577/3415641
http://hdl.handle.net/11577/3415641
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 15:595-604
The effects of two nights of treatment with the short-acting benzodiazepine receptor agonist zaleplon, triazolam, or placebo was assessed in chronic primary insomniacs using two concurrent, multi-center, randomized, double-blind, Latin Square crossov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a832636729c992df035ff83474e3a6d6
https://doi.org/10.1002/hup.216
https://doi.org/10.1002/hup.216
Publikováno v:
Journal of Medicinal Chemistry. 36:3533-3541
Previous pharmacological studies of methylated oxotremorine derivatives bearing substituents at the 3-, 4-, and 5-positions of the pyrrolidinone ring have been conducted using racemic mixtures, and not with optically active compounds. The synthesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84765a6ed07424c3626d931e68ef7cb9
https://doi.org/10.1021/jm00075a007
https://doi.org/10.1021/jm00075a007
Autor:
Gerardo D. Francisco, Herbert J. Brabander, Richard M. Mangano, Richard H. Kramss, Eugene J. Trybulski
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:827-832
The synthesis and radioligand binding data of optically active hydroxylated oxotremorine derivatives are described. These are significant pharmacological differences between the enantiomers, most notably at the 3- and 4-position of the pyrrolidinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92eafcabe8e94b74a2f7c683c87551b3
https://doi.org/10.1016/s0960-894x(00)80539-9
https://doi.org/10.1016/s0960-894x(00)80539-9
Publikováno v:
Journal of Medicinal Chemistry. 33:3190-3198
A series of optically pure 2-[substituted-3-aminopropynyl]pyrrolidine derivatives, which are restricted-rotation analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide (BM-5, compound 1), have been prepared from d- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5b17da2dad8ed9ee1cbfd8c81c4966
https://doi.org/10.1021/jm00174a015
https://doi.org/10.1021/jm00174a015
Autor:
Gary K, Zammit, Bruce, Corser, Karl, Doghramji, June M, Fry, Steven, James, Andrew, Krystal, Richard M, Mangano
Publikováno v:
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2(4)
To assess the efficacy of zaleplon 10 mg and zolpidem 10 mg administered during experimental middle-of-the-night awakenings in patients with sleep-maintenance insomnia using objective polysomnographic measures and to assess daytime residual sedation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::011caeed285ece77c69cc36711fef714
https://pubmed.ncbi.nlm.nih.gov/17557470
https://pubmed.ncbi.nlm.nih.gov/17557470
A randomized controlled trial of venlafaxine extended release in generalized social anxiety disorder
Publikováno v:
The Journal of clinical psychiatry. 66(2)
BACKGROUND: Generalized social anxiety disorder is a debilitating psychiatric illness characterized by maladaptive thoughts about social situations. This double-blind study evaluated the anxiolytic efficacy, safety, and tolerability of venlafaxine ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce4b99af71a77bea99a255afb643f49
https://pubmed.ncbi.nlm.nih.gov/15705011
https://pubmed.ncbi.nlm.nih.gov/15705011
Autor:
Walter S. Jones, Gary S. Richardson, Richard M. Mangano, Phil Hall, Sonia Ancoli-Israel, Lisa Jenkins
Publikováno v:
Sleep medicine. 6(2)
Insomnia is a common problem that increases with age and can last months to years. While substantial data establish the efficacy and safety of short-acting hypnotic therapy for the management of short-term insomnia using benzodiazepines receptor agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62cca4f92a03942dda15ad72a1b473a
https://pubmed.ncbi.nlm.nih.gov/15716214
https://pubmed.ncbi.nlm.nih.gov/15716214
Publikováno v:
Human psychopharmacology. 15(8)
The effects of two nights of treatment with the short-acting benzodiazepine receptor agonist zaleplon, triazolam, or placebo was assessed in chronic primary insomniacs using two concurrent, multi-center, randomized, double-blind, Latin Square crossov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c124a45a292762c1bd18c7d122b9b6e9
https://pubmed.ncbi.nlm.nih.gov/12404612
https://pubmed.ncbi.nlm.nih.gov/12404612
Publikováno v:
Sleep medicine. 2(4)
Objectives and background: Given that non-selective gamma-aminobutyric acid (GABA) agonist hypnotics impair performance and potentiate the disruptive effects of ethanol, this study was done to determine the performance-impairing and ethanol-potentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de95a204cf4c80d0562a82c1a8257c6e
https://pubmed.ncbi.nlm.nih.gov/11438249
https://pubmed.ncbi.nlm.nih.gov/11438249