Výsledky vyhledávání - "Richard Lipkin"

Computational prediction of the optimal oligomeric state for membrane‐inserted β ‐barrels of protegrin‐1 and related mutants

Autor: Themis Lazaridis, Richard Lipkin

Publikováno v: Journal of Peptide Science. 23:334-345

Protegrin-1 is a widely studied 18-residue β-hairpin antimicrobial peptide. Evidence suggests that it acts via a β-barrel pore formation mechanism, but the exact number of peptides comprising the pore state is unknown. In this study, we performed m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a8db85ed6003991bcde966d010c543
https://doi.org/10.1002/psc.2992

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Transmembrane Pore Structures of β-hairpin Antimicrobial Peptides by All-Atom Simulations

Autor: Almudena Pino-Angeles, Richard Lipkin, Themis Lazaridis

Protegrin-1 is an 18-residue β-hairpin antimicrobial peptide (AMP) that has been suggested to form transmembrane β-barrels in biological membranes. However, alternative structures have also been proposed. Here, we performed multimicrosecond, all-at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fd5d46775bae23baf92d70ef094e44
https://europepmc.org/articles/PMC5686775/

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Computational studies of peptide-induced membrane pore formation

Autor: Richard Lipkin, Themis Lazaridis

Publikováno v: Philosophical Transactions of the Royal Society B: Biological Sciences. 372:20160219

A variety of peptides induce pores in biological membranes; the most common ones are naturally produced antimicrobial peptides (AMPs), which are small, usually cationic, and defend diverse organisms against biological threats. Because it is not possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f590e4b373f43b3f90eed9bef0c8594a
https://doi.org/10.1098/rstb.2016.0219

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Reliable and durable Golgi staining of brain tissue from human autopsies and experimental animals

Autor: Tatiana P. Schnieder, Richard Lipkin, Vladimir M. Petrushevski, Zlatko Jakovski, Aleksej Duma, Aleksandar Stankov, Kimberley Scobie, Ani Dika, Natasha Davcheva, Andrew J. Dwork, Gorazd Rosoklija, Goran Pavlovski

Publikováno v: Journal of neuroscience methods. 230

Background Golgi stains are notoriously capricious, particularly when applied to human brain. The well-known difficulties, which include complete failure of impregnation, patchy staining, unstable staining, and extensive crystalline deposits in super

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe459fcb1699997725916c17439728a
https://pubmed.ncbi.nlm.nih.gov/24747874

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Regional Cerebral Blood Flow and Metabolic Rate in Persistent Lyme Encephalopathy

Autor: Iordan Slavov, Ronald L. Van Heertum, Brett D. Mensh, Shan Yu, James R. Moeller, Kathy M. Corbera, Eva Petkova, Harold A. Sackeim, Brian A. Fallon, Richard Lipkin, Sarah H. Lisanby, Mitchell S. Nobler, John G. Keilp

Context: There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease. Objectives: To determine whether patients with a history of well-characterized Lyme disease and persi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dd671bb00ef349ac1ab41f991cb9a7

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