Disrupted brain connectivity in children treated with therapeutic hypothermia for neonatal encephalopathy

Autor: Arthur P.C. Spencer, Jonathan C.W. Brooks, Naoki Masuda, Hollie Byrne, Richard Lee-Kelland, Sally Jary, Marianne Thoresen, James Tonks, Marc Goodfellow, Frances M. Cowan, Ela Chakkarapani

Publikováno v: NeuroImage: Clinical, Vol 30, Iss , Pp 102582- (2021)

Therapeutic hypothermia following neonatal encephalopathy due to birth asphyxia reduces death and cerebral palsy. However, school-age children without cerebral palsy treated with therapeutic hypothermia for neonatal encephalopathy still have reduced

Externí odkaz: https://doaj.org/article/f19465b1a5f5401fbce7969fbfcb9535

Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects.

Autor: John Dingley, Satomi Okano, Richard Lee-Kelland, Emma Scull-Brown, Marianne Thoresen, Ela Chakkarapani

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0224447 (2020)

BackgroundTherapeutic hypothermia (TH) for 72h is the standard treatment following neonatal encephalopathy (NE). However, one-third do not benefit and adjunctive therapies are urgently needed. Xenon enhances neuroprotection with TH when administered

Externí odkaz: https://doaj.org/article/7764e550cce54e459c28ce0b2c007c77

1417 Identifying and addressing parental concerns regarding head banging in early childhood: a review of the literature

Autor: Josephine Harrison, Richard Lee-Kelland

Publikováno v: British Association for Community Child Health.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c84dbee7f832e17c7e6396300b837088
https://doi.org/10.1136/archdischild-2022-rcpch.143

Brain volumes and functional outcomes in children without cerebral palsy after therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy

Autor: Arthur P. C. Spencer, Richard Lee‐Kelland, Jonathan C. W. Brooks, Sally Jary, James Tonks, Frances M. Cowan, Marianne Thoresen, Ela Chakkarapani

Publikováno v: Spencer, A P C, Lee-Kelland, R, Brooks, J C W, Jary, S, Tonks, J, Cowan, F M, Thoresen, M & Chakkarapani, E 2022, ' Brain volumes and functional outcomes in children without cerebral palsy after therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy ', Developmental Medicine and Child Neurology . https://doi.org/10.1111/dmcn.15369

AIM: To investigate whether brain volumes were reduced in children aged 6 to 8 years without cerebral palsy, who underwent therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy (patients), and matched controls, and to examine the rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af21d3bb7bd0162113774c3f5696fa9
https://research-information.bris.ac.uk/en/publications/739007bf-f216-4cdf-a153-eac7ad25ba03

Motor function and white matter connectivity in children cooled for neonatal encephalopathy

Autor: Richard Lee-Kelland, Frances M. Cowan, Jonathan C W Brooks, Naoki Masuda, Marc Goodfellow, Marianne Thoresen, Elavazhagan Chakkarapani, Sally Jary, Hollie Byrne, Arthur P.C. Spencer

Publikováno v: NeuroImage : Clinical
NeuroImage: Clinical, Vol 32, Iss, Pp 102872-(2021)
Spencer, A, Brooks, J C W, Masuda, N, Byrne, H, Lee-Kelland, R, Jary, S L, Thoresen, M, Goodfellow, M, Cowan, F & Chakkarapani, E 2021, ' Motor function and white matter connectivity in children cooled for neonatal encephalopathy ', NeuroImage: Clinical, vol. 32, 102872 . https://doi.org/10.1016/j.nicl.2021.102872

Highlights • Cases were children cooled for neonatal encephalopathy, without cerebral palsy. • Controls were matched for age, sex and socioeconomic status. • In cases, tract-level fractional anisotropy correlated with motor performance. • Gra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ec1055f8487a212ef1e89c4c500f65
https://pubmed.ncbi.nlm.nih.gov/34749285