Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Richard Laverty"'
Autor:
Janet M. Ledingham, Richard Laverty
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32:76-85
SUMMARY 1. The aims of the present study were to investigate, in the New Zealand genetically hypertensive (GH) rat model, the effects of treatment with simvastatin, alone or in combination with valsartan or enalapril, on blood pressure (BP) and struc
Autor:
Richard Laverty, Bruce R. Russell
Publikováno v:
Pharmacology Biochemistry and Behavior. 68:565-574
The glycine site-specific N-methyl-D-aspartate (NMDA) antagonist 5-nitro-6,7-dichloro-2,3-quinoxalinedione (ACEA 1021, 4x30 mg/kg, i.p.) given 30 min before dexfenfluramine (4x15 mg/kg, i.p., every 2 h) was unable to prevent dexfenfluramine-induced d
Publikováno v:
Brain Research. 882:45-54
Previous studies have demonstrated that vestibular compensation, the process of behavioural recovery which occurs following unilateral deafferentation of the vestibular labyrinth (UVD), is correlated with changes in in vitro phosphorylation of variou
Autor:
Richard Laverty, Bruce R. Russell
Publikováno v:
Annals of the New York Academy of Sciences. 914:208-214
3,4-Methylenedioxymethamphetamine (MDMA) and fenfluramine are amphetamine analogues that both cause long-term depletion of serotonin (5-HT) and 5-HT uptake sites in brain tissue. Depletion caused by these amphetamines is commonly measured by labeling
Autor:
Janet M. Ledingham, Richard Laverty
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 27:642-646
SUMMARY 1. The structure of the basilar artery and the relationship of structure to blood pressure and ventricular hypertrophy was examined in genetically hypertensive (GH) rats, their control normotensive (N) Wistar strain, GH given the nitric oxide
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 27:488-493
SUMMARY 1. The possible role of an endothelial defect in the hypertension of the New Zealand genetically hypertensive (GH) rat strain was assessed by examining cardiovascular responses to the nitric oxide synthase (NOS) inhibitor Nω-nitro- L-arginin
Publikováno v:
Neuroscience Letters. 283:117-120
We investigated the effects of a non-competitive N -methyl- d -aspartate (NMDA) receptor/channel antagonist ((+)MK-801)) or an L-type Ca 2+ channel antagonist (nifedipine), delivered into the ipsilateral vestibular nucleus complex (VNC) before a unil
Publikováno v:
Journal of Vascular Research. 37:134-145
The relative efficacy of three antihypertensive drugs in the prevention of further elevation of blood pressure (BP) and cardiovascular structural remodeling in 4-week-old genetically hypertensive (GH) rats was studied by means of two complementary me
Autor:
Cynthia L. Darlington, Paul F. Smith, DeWana R. Kerr, Allison R Moulton, Andrew J. Sansom, Tamaryn V Anderson, Richard Laverty
Publikováno v:
Brain Research. 787:311-314
The aim of the present study was to examine, using a radioenzymatic assay technique, nitric oxide synthase (NOS) activity in the bilateral medial vestibular nuclei (MVN) and prepositus hypoglossi (PH), during the development of vestibular compensatio
Autor:
Paul F. Smith, Richard Laverty, John A.P. Rostas, Vicki A. Brent, Cynthia L. Darlington, Andrew J. Sansom, Paula E. Jarvie
Publikováno v:
Brain Research. 778:166-177
Unilateral removal of vestibular nerve input to the vestibular nuclei (e.g. by unilateral labyrinthectomy, UL) results in severe ocular motor and postural disorders which disappear over time (vestibular compensation). We investigated whether recovery