Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Richard Lauman"'
Autor:
Jean M. Etersque, Iris K. Lee, Nitika Sharma, Kexiang Xu, Andrew Ruff, Justin D. Northrup, Swarbhanu Sarkar, Tommy Nguyen, Richard Lauman, George M. Burslem, Mark A. Sellmyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Temporal control of protein levels in cells and living animals can be used to improve our understanding of protein function. In addition, control of engineered proteins could be used in therapeutic applications. PRoteolysis-TArgeting Chimera
Externí odkaz:
https://doaj.org/article/37f8ccd04b6741fe96a85487d62b0e1e
Autor:
Alexander M Price, Robert T Steinbock, Richard Lauman, Matthew Charman, Katharina E Hayer, Namrata Kumar, Edwin Halko, Krystal K Lum, Monica Wei, Angus C Wilson, Benjamin A Garcia, Daniel P Depledge, Matthew D Weitzman
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010797 (2022)
Adenovirus is a common human pathogen that relies on host cell processes for transcription and processing of viral RNA and protein production. Although adenoviral promoters, splice junctions, and polyadenylation sites have been characterized using lo
Externí odkaz:
https://doaj.org/article/eaab36792be84a51a07f2ccdca52cc19
Autor:
Joseph M. Dybas, Krystal K. Lum, Katarzyna Kulej, Emigdio D. Reyes, Richard Lauman, Matthew Charman, Caitlin E. Purman, Robert T. Steinbock, Nicholas Grams, Alexander M. Price, Lydia Mendoza, Benjamin A. Garcia, Matthew D. Weitzman
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. Adenovirus (AdV) encodes pro
Externí odkaz:
https://doaj.org/article/8263a46ee7ba41df86e9a00e6d03a9fc
Autor:
Richard Lauman, Hee Jong Kim, Lindsay K. Pino, Alessandro Scacchetti, Yixuan Xie, Faith Robison, Simone Sidoli, Roberto Bonasio, Benjamin A. Garcia
Publikováno v:
Analytical Chemistry. 95:5187-5195
Autor:
Richard Lauman, Hee Jong Kim, Lindsay K. Pino, Alessandro Scacchetti, Roberto Bonasio, Benjamin A. Garcia
Post-transcriptional modifications of RNA strongly influence RNA structure and function. Recent advances in RNA sequencing and mass spectrometry (MS) methods have identified over 140 of these modifications on a wide variety of RNA species. Most next-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27e7a0e1f04defcda7d6573a28388fe
https://doi.org/10.1101/2022.10.28.514273
https://doi.org/10.1101/2022.10.28.514273
Autor:
Ozgur Oksuz, Jonathan E Henninger, Robert Warneford-Thomson, Ming M Zheng, Hailey Erb, Kalon J Overholt, Susana Wilson Hawken, Salman F Banani, Richard Lauman, Adrienne Vancura, Anne L Robertson, Nancy M Hannett, Tong I Lee, Leonard I. Zon, Roberto Bonasio, Richard A. Young
SummaryTranscription factors (TFs) orchestrate the gene expression programs that define each cell’s identity. The canonical TF accomplishes this with two domains, one that binds specific DNA sequences and the other that binds protein coactivators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26928fddc2278ca573e0a0d65d77f09
https://doi.org/10.1101/2022.09.27.509776
https://doi.org/10.1101/2022.09.27.509776
Autor:
Richard Lauman, Alexander M. Price, Caitlin E. Purman, Joseph M Dybas, Eui Tae Kim, Katharina E. Hayer, Matthew D. Weitzman, Benjamin A. Garcia, Jennifer C. Liddle, Matthew Charman, Christin Herrmann
Publikováno v:
Nature microbiology
Viruses promote infection by hijacking the ubiquitin machinery of the host to counteract or redirect cellular processes. Adenovirus encodes two early proteins, E1B55K and E4orf6, that together co-opt a cellular ubiquitin ligase complex to overcome ho
Autor:
Matthew Charman, Richard Lauman, Joseph M Dybas, Nicholas Grams, Alexander M. Price, Caitlin E. Purman, Matthew D. Weitzman, Emigdio D. Reyes, Robert T Steinbock, Benjamin A. Garcia, Krystal K Lum, Katarzyna Kulej, Lydia Mendoza
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. Adenovirus (AdV) encodes proteins fro
Autor:
Brady M. Owen, Vitalina Levina, Qi Zhang, Chen Davidovich, Robert Warneford-Thomson, Roberto Bonasio, Benjamin A. Garcia, Ralf B. Schittenhelm, Nicholas J. McKenzie, Emma H Gail, Sarena F. Flanigan, Richard Lauman
Publikováno v:
Nature Structural & Molecular Biology. 26:237-247
Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that maintains cell identity during development in multicellular organisms by marking repressed genes and chromatin domains. In addition to four core subunits, PRC2 comprises multipl
Publikováno v:
J Proteome Res
Stable isotope labeling by amino acids in cell culture (SILAC) coupled to data-dependent acquisition (DDA) is a common approach to quantitative proteomics with the desirable benefit of reducing batch effects during sample processing and data acquisit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e660bb8e1e743bc4c42abc7dec28b291
https://doi.org/10.1101/2020.11.23.394304
https://doi.org/10.1101/2020.11.23.394304