Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Richard Langford"'
Autor:
Eugene R. Viscusi, Richard Langford, Adelaida Morte, Anna Vaqué, Jesús Cebrecos, Mariano Sust, José María Giménez-Arnau, Oscar de Leon-Casasola
Publikováno v:
Pain and Therapy, Vol 13, Iss 6, Pp 1617-1631 (2024)
Abstract Introduction Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower doses, thereby aiding tolerability. Co-crystal of tramadol-celecoxib (CTC) provides effective analgesia in m
Externí odkaz:
https://doaj.org/article/915a54414edb4cf9857235723f72b67d
Autor:
Richard Langford, Eugene R. Viscusi, Adelaida Morte, Jesús Cebrecos, Mariano Sust, José María Giménez-Arnau, Oscar de Leon-Casasola
Publikováno v:
Drugs in R&D, Vol 24, Iss 2, Pp 239-252 (2024)
Abstract Background and Objectives New acute pain medications are needed that provide effective analgesia while minimizing side effects and opioid exposure. Clinical trials of co-crystal of tramadol-celecoxib (CTC) have demonstrated an improved benef
Externí odkaz:
https://doaj.org/article/19b3c818f9a44197b7fa0da272900cc9
Autor:
Kate Clouse, Tamsin K. Phillips, Carol Camlin, Sandisiwe Noholoza, Phepo Mogoba, Julian Naidoo, Richard Langford, Martin Weiss, Christopher J. Seebregts, Landon Myer
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background South Africa is home to the world’s largest antiretroviral therapy program but sustaining engagement along the HIV care continuum has proven challenging in the country and throughout the wider region. Population mobility is comm
Externí odkaz:
https://doaj.org/article/14de5912a8bc43349d5f246a45bdb5b5
Autor:
Saowarat Snidvongs, Rod S Taylor, Alia Ahmad, Simon Thomson, Manohar Sharma, Angela Farr, Deborah Fitzsimmons, Stephanie Poulton, Vivek Mehta, Richard Langford
Publikováno v:
Health Technology Assessment, Vol 21, Iss 74 (2017)
Background: Pain of lumbar facet-joint origin is a common cause of low back pain in adults and may lead to chronic pain and disability, with associated health and socioeconomic implications. The socioeconomic burden includes an inability to return to
Externí odkaz:
https://doaj.org/article/9aae17d8d7954a4c83e49cf40d1e52a7
Autor:
Giarlã Cunha da Silva, Ciro César Rossi, Jéssica Nogueira Rosa, Newton Moreno Sanches, Daniela Lopes Cardoso, Yanwen Li, Adam A. Witney, Kate A. Gould, Patrícia Pereira Fontes, Anastasia J. Callaghan, Janine Thérèse Bossé, Paul Richard Langford, Denise Mara Soares Bazzolli
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The RNA chaperone Hfq promotes the association of small RNAs (sRNAs) with cognate mRNAs, controlling the expression of bacterial phenotype. Actinobacillus pleuropneumoniae hfq mutants strains are attenuated for virulence in pigs, impaired in the abil
Externí odkaz:
https://doaj.org/article/249d529d4dab412a83c9fb9879da4290
Autor:
Giarlã Cunha da Silva, Osiel Silva Gonçalves, Jéssica Nogueira Rosa, Kiara Campos França, Janine Thérèse Bossé, Mateus Ferreira Santana, Paul Richard Langford, Denise Mara Soares Bazzolli
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Mobile genetic elements (MGEs) and antimicrobial resistance (AMR) drive important ecological relationships in microbial communities and pathogen-host interaction. In this study, we investigated the resistome-associated mobilome in 345 publicly availa
Externí odkaz:
https://doaj.org/article/af88491d84dd413784a9e27218eb77b8
Autor:
Wang, Lei, Zhao, Xueqin, Zhu, Chunling, Xia, Xiaojing, Qin, Wanhai, Li, Mei, Wang, Tongzhao, Chen, Shijun, Xu, Yanzhao, Hang, Bolin, Sun, Yawei, Jiang, Jinqing, Richard, Langford Paul, Lei, Liancheng, Zhang, Gaiping, Hu, Jianhe
Publikováno v:
In Veterinary Microbiology May 2017 203:202-210
Autor:
Richard Langford, Adelaida Morte, Mariano Sust, Jesús Cebrecos, Anna Vaqué, Esther Ortiz, James Fettiplace, Shola Adeyemi, Grzegorz Raba, Liudmila But‐Husaim, Neus Gascón, Carlos Plata‐Salamán
Publikováno v:
European Journal of Pain. 26:2083-2096
STARDOM2 is a randomized, double-blind, phase 3 trial evaluating the efficacy and safety of co-crystal of tramadol-celecoxib (CTC)-a first-in-class analgesic co-crystal comprising racemic tramadol hydrochloride and celecoxib in a supramolecular netwo
Autor:
Richard Langford, Michael Husband, Alexander Oksche, John G. Gribben, Alla Belhaj, Robert D. Petty, Farideh Miraki-Moud, Nilesh Randive, Mary Elizabeth Demopoulos, Theresa Wodehouse, Laura Fulton, Vivek Mehta
Publikováno v:
Pain. 160:2691-2698
Endogenous opioid peptides and exogenous opioids modulate immune function, and animal and human studies have shown that some have a depressant immunomodulatory effect. This is potentially of high clinical significance, eg, in cancer patients and surg
Autor:
Cunha da Silva, Giarlã, César Rossi, Ciro, Nogueira Rosa, Jéssica, Moreno Sanches, Newton, Lopes Cardoso, Daniela, Yanwen Li, Witney, Adam A., Gould, Kate A., Pereira Fontes, Patrícia, Callaghan, Anastasia J., Thérèse Bossé, Janine, Richard Langford, Paul, Soares Bazzolli, Denise Mara
Publikováno v:
Frontiers in Microbiology; 10/4/2022, Vol. 13, p1-20, 20p