Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Richard L. Yates"'
Publikováno v:
Brain Communications. 5
Cerebral cortical inflammation and neurodegeneration are hallmark pathological features of multiple sclerosis that contribute to irreversible neurological disability. While the reason for nerve cell death is unknown, the pathogenic inflammatory role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6039554682bc5deee47c9914f7de2c20
https://doi.org/10.1093/braincomms/fcad072
https://doi.org/10.1093/braincomms/fcad072
Autor:
Margaret M. Esiri, Richard L. Yates, Benjamin Meir Jacobs, Gabriele C. DeLuca, Jacqueline Palace, Rafael Perera
Publikováno v:
Annals of Neurology. 82:259-270
© 2017 American Neurological Association Objective: Neuronal loss, a key substrate of irreversible disability in multiple sclerosis (MS), is a recognized feature of MS cortical pathology of which the cause remains unknown. Fibrin(ogen) deposition is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c91f8136ca83cc01ec0cef5931fb80a8
https://doi.org/10.1002/ana.24997
https://doi.org/10.1002/ana.24997
Autor:
Jonathan I Spencer, Richard L. Yates, Jack S. Bell, Benjamin Meir Jacobs, S. A. Yee, Gabriele C. DeLuca
Inflammation and neurodegeneration are key features of many chronic neurological diseases, yet the causative mechanisms underlying these processes are poorly understood. There has been mounting interest in the role of the human microbiome in modulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0418fa49563011c790eeafcc94836b9
https://ora.ox.ac.uk/objects/uuid:933cb5fc-dc82-4242-aa58-7add367957eb
https://ora.ox.ac.uk/objects/uuid:933cb5fc-dc82-4242-aa58-7add367957eb
Despite the historical focus on white matter pathology, it is now increasingly recognised that cortical tissue injury is critical to disease outcome. Cortical pathology occurs from the earliest disease stages, predominates in progressive MS, and corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbeec7689aeebafc2cad1c040d96923
https://doi.org/10.1007/s00415-017-8727-1
https://doi.org/10.1007/s00415-017-8727-1
Publikováno v:
Neuropathology and Applied Neurobiology. 41:371-384
Aim Multiple sclerosis (MS) is a common and heterogeneous CNS inflammatory demyelinating disease. The HLA-DRB1 locus may influence clinical outcome. MS cortical pathology is frequent and correlates with measures of clinical disability, including moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e805dd9076228ebb4cd3d463a5df901
https://doi.org/10.1111/nan.12165
https://doi.org/10.1111/nan.12165
Publikováno v:
Brain Pathology. 25:79-98
Cognitive impairment is a common and debilitating feature of multiple sclerosis (MS) that has only recent gained considerable attention. Clinical neuropsychological studies have made apparent the multifaceted nature of cognitive troubles often encoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fab0206596672f0ebda14f6094e68e
https://doi.org/10.1111/bpa.12220
https://doi.org/10.1111/bpa.12220
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 24(6)
Substantial evidence suggests that cortical tissue injury plays a key role in the progression of permanent disability in multiple sclerosis (MS). Cortical demyelination occurs early, becomes more extensive with time and eventually exceeds the extent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83b1c86b3280b89f5be86d819e1a1c4
https://pubmed.ncbi.nlm.nih.gov/28994641
https://pubmed.ncbi.nlm.nih.gov/28994641
Autor:
Francesco Grussu, Hui Zhang, Andrada Ianus, Carmen Tur, Richard L. Yates, Marios C. Yiannakas, Claudia A. M. Wheeler-Kingshott, Mohamed Tachrount, Jia Newcombe, Torben Schneider, Gabriele C. DeLuca, Daniel C. Alexander
Publikováno v:
Annals of Clinical and Translational Neurology
Objective: Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal cord is limited by low specificity regarding the underlying pathological processes, and new MRI metrics assessing microscopic damage are required. We aim to sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30b9412c7d90238d13fb784f879fe05
Autor:
Margaret M. Esiri, Gabriele C. DeLuca, Jithin George, Albert Joseph, Richard L. Yates, Monika Hofer, Marie Hamard
Publikováno v:
Brain Pathology. 25:543-551
Olfactory dysfunction is common in multiple sclerosis (MS). Olfactory bulb and tract pathology in MS and other demyelinating diseases remain unexplored. A human autopsy cohort of pathologically confirmed cases encompassing the spectrum of demyelinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b0f0dd5ec6e841f54a8807b93d51a4
https://doi.org/10.1111/bpa.12209
https://doi.org/10.1111/bpa.12209
Autor:
Gabriele C. DeLuca, Richard L. Yates
Publikováno v:
Multiple Sclerosis and Related Disorders. 19:166-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a369dec9052b30464a5bfc0255e4d4
https://doi.org/10.1016/j.msard.2016.08.005
https://doi.org/10.1016/j.msard.2016.08.005