Zobrazeno 1 - 10 of 64 pro vyhledávání: '"Richard L. Siegler"'
1
Predictors of Fatality in Postdiarrheal Hemolytic Uremic Syndrome
Autor: Markham A McReynolds, Andrew T. Pavia, Theodore J. Pysher, Richard L. Siegler, Robert S. Oakes
Publikováno v: Pediatrics. 117:1656-1662
OBJECTIVES. Describe the cause of deaths among patients with postdiarrheal hemolytic uremic syndrome (HUS) and identify predictors of death at the time of hospital admission.METHODS. Case-control study of 17 deaths among patients with HUS identified
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f68efb4aec512d8b8ce9e4029f78bc9
https://doi.org/10.1542/peds.2005-0785
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2
Hemolytic uremic syndrome; pathogenesis, treatment, and outcome
Autor: Richard L. Siegler, Robert S. Oakes
Publikováno v: Current Opinion in Pediatrics. 17:200-204
The hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in infants and young children, and is a substantial cause of acute mortality and chronic morbidity. It is therefore relevant and appropriate that pediatricians remain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b17a00feae99018761a48cf535aed5e
https://doi.org/10.1097/01.mop.0000152997.66070.e9
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3
Contents Vol. 25, 2005
Autor: Melvin R. Hayden, Natan Cohen, Andrea Galassi, Pamela Schinleber, Marco Antonio P. Leite, David L. Gasser, Michael Rapoport, Hongqi Ren, Shai Efrati, Daniel J. Rader, Zhihong Liu, Barry I. Freedman, Laurie Roberts, David Modai, Wayne W. Hancock, James R. Sowers, Ahuva Golik, Federica Cecchini, Jin Kim, Caihong Zeng, Frederic Clayton, John E. Tomaszewski, Krystyna Pawlak, Joshua Weissgarten, Renata C. Santos, In San Kim, Leishi Li, Cristianne L. Fabris, Michael P. Madaio, Jung Ho Cha, Huiping Chen, Adam Whaley-Connell, Walid Ghantous, James M. Bates, Guillermo Coca Velarde, Can Li, Stuart M. Sprague, Min Peng, Vernon L. Tesh, Chul Woo Yang, Claudine Jurkovitz, F.M. Ribeiro, William M. McClellan, Michal Mysliwiec, Jolanta Malyszko, Hajamohideen S. Raffi, Mordechay Aladjem, Guang Yang, Jacek S. Malyszko, Donald E. Kohan, Nataliya V. Volkova, Domenico Russo, Satish Kumar, Zoltan Laszik, Jocemir Ronaldo Lugon, Olivia Turri, Suk Hee Lee, Alberto Mendoza, Ray Meade, Elena Galperin, Scott G. Satko, Nathaniel D. Denkers, J. Michael Soucie, Rexford S. Ahima, Maria Luisa Biondi, Tomasz Hryszko, Anna L. Zisman, Fletcher B. Taylor, Richard L. Siegler, Sun Woo Lim, Bum Soon Choi, Theodore J. Pysher, Vittorio E. Andreucci, Hong Zhou, Maurizio Gallieni, Jenna Krisher, Diego Brancaccio, Mario Cozzolino, Sylvia Berman, Zhan Averbukh, Randall Lou, Zheng Tang
Publikováno v: American Journal of Nephrology. 25:627-630
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bd57c9798dcabc871200418ce3daa8a
https://doi.org/10.1159/000090454
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4
Lipopolysaccharide Upregulates Renal Shiga Toxin Receptors in a Primate Model of Hemolytic Uremic Syndrome
Autor: Randall Lou, Theodore J. Pysher, Vernon L. Tesh, Richard L. Siegler, Fletcher B. Taylor, Donald E. Kohan, Frederic Clayton, Nathaniel D. Denkers
Publikováno v: American Journal of Nephrology. 25:536-540
Background: Although Shiga toxin (Stx) mediates classical hemolytic uremic syndrome (HUS), it is not fully understood why only some subjects exposed to Stx-expressing Escherichia coli develop HUS. We have previously shown in a baboon model of Stx-med
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e828cba9ebc9d93eb000d20dbfd86897
https://doi.org/10.1159/000088523
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5
Prophylactic heparinization is ineffective in a primate model of hemolytic uremic syndrome
Autor: Theodore J. Pysher, Fletcher B. Taylor, Richard L. Siegler, Vernon L. Tesh, Nathaniel D. Denkers
Publikováno v: Pediatric Nephrology. 17:1053-1058
The presence of abundant fibrin within the glomerular capillaries of patients with Shiga toxin (Stx)-mediated (post-diarrheal) hemolytic uremic syndrome (HUS) has suggested that heparin anticoagulation might be useful in the treatment of this disease
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6becc3a36957d5179f549e9b75c7ac43
https://doi.org/10.1007/s00467-002-1002-3
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7
Renal Prostacyclin Biosynthesis in a Baboon Model of Shiga Toxin Mediated Hemolytic Uremic Syndrome
Autor: Richard L. Siegler, Vernon L. Tesh, Theodore J. Pysher, Fletcher B. Taylor
Publikováno v: Nephron. 92:363-368
Background/Aims: Shiga toxin (Stx) and lipopolysaccharide (LPS) both participate in the pathogenesis of post-diarrheal (D+) hemolytic uremic syndrome (HUS), but little is known about factors that modulate the host response to these toxins. Prostacycl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df6e2a6e6a744e52f448a447bd17742
https://doi.org/10.1159/000063310
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8
Response to Single and Divided Doses of Shiga Toxin-1 in a Primate Model of Hemolytic Uremic Syndrome
Autor: Theodore J. Pysher, Vernon L. Tesh, Fletcher B. Taylor, Richard L. Siegler
Publikováno v: Journal of the American Society of Nephrology. 12:1458-1467
Postdiarrheal hemolytic uremic syndrome is caused by Shiga toxin (Stx)-producing Escherichia coli. It was shown previously that the baboon, like the human, has glycolipid receptors for Stx in the gut and the kidney and that a single 50- to 200-ng/kg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0d0c3278e2120673e9a27974c0d7bc
https://doi.org/10.1681/asn.v1271458
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9
Response to Shiga Toxin-1, with and without Lipopolysaccharide, in a Primate Model of Hemolytic Uremic Syndrome
Autor: Vernon L. Tesh, Richard L. Siegler, Theodore J. Pysher, Randall Lou, Fletcher B. Taylor
Publikováno v: American Journal of Nephrology. 21:420-425
Shiga toxin (Stx) and lipopolysaccharide (LPS) both participate in the pathogenesis of post-diarrheal hemolytic uremic syndrome (HUS), yet little is known about the factors that modulate the host response to these toxins. We have previously shown tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc96f52f1dab38efd604308719c7c3fe
https://doi.org/10.1159/000046288
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10
Characterization of the Baboon Responses to Shiga-Like Toxin
Autor: Richard L. Siegler, Vernon L. Tesh, Fletcher B. Taylor, Alvin C. K. Chang, Theodore J. Pysher, Lawrence DeBault, Stanley D. Kosanke, Anguo Li
Publikováno v: The American Journal of Pathology. 154:1285-1299
The baboon response to intravenous infusion of Shiga toxin 1 (Stx-1) varied from acute renal failure, proteinuria, hyperkalemia, and melena with minimal perturbation of host inflammatory and hemostatic systems (high-dose group, 2.0 μg/kg; n = 5) to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d55d610afa47566270f2e20d02f288c
https://doi.org/10.1016/s0002-9440(10)65380-1
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