Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Richard L. Moss"'
Autor:
Jitandrakumar R. Patel, Gregory P. Barton, Rudolf K. Braun, Kara N. Goss, Kristin Haraldsdottir, Alexandria Hopp, Gary Diffee, Timothy A. Hacker, Richard L. Moss, Marlowe W. Eldridge
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Infants born premature are at increased risk for development of bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), and ultimately right ventricular (RV) dysfunction, which together carry a high risk of neonatal mortality. However, the rol
Externí odkaz:
https://doaj.org/article/a1243ca405c64505825663d84c20edea
Autor:
Willem J. De Lange, Emily T. Farrell, Jonathan J. Hernandez, Alana Stempien, Caroline R. Kreitzer, Derek R. Jacobs, Dominique L. Petty, Richard L. Moss, Wendy C. Crone, J. Carter Ralphe
Publikováno v:
Journal of General Physiology. 155
Truncation mutations in cardiac myosin binding protein C (cMyBP-C) are common causes of hypertrophic cardiomyopathy (HCM). Heterozygous carriers present with classical HCM, while homozygous carriers present with early onset HCM that rapidly progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f148b02a41d4bfbb7519538279deb4
https://doi.org/10.1085/jgp.202213204
https://doi.org/10.1085/jgp.202213204
Autor:
Hannah Karp, J. Carter Ralphe, Zachery R. Gregorich, Willem J. de Lange, Timothy J. Kamp, Ying Ge, Elizabeth F. Bayne, Trisha Tucholski, Wenxuan Cai, Joshua L. Hermsen, Sean J. McIlwain, Amy Li, Steven B. Marston, Stanford D. Mitchell, Petr G. Vikhorev, Zachary Hite, Cristobal G. dos Remedios, Max Wrobbel, Sean Lal, Takushi Kohmoto, Richard L. Moss
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease and a leading cause of sudden cardiac death in young adults. HCM has been linked to mutations in genes encoding sarcomeric proteins, but how different mutations can resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6425102d14355d69e24e9eb68fbd7321
https://doi.org/10.1073/pnas.2006764117
https://doi.org/10.1073/pnas.2006764117
Autor:
Judith Kimble, William M Bement, Qiang Chang, Benjamin L Cox, Norman R Drinkwater, Richard L Gourse, Aaron A Hoskins, Anna Huttenlocher, Pamela K Kreeger, Paul F Lambert, Marsha R Mailick, Shigeki Miyamoto, Richard L Moss, Kate M O'Connor-Giles, Avtar Roopra, Krishanu Saha, Hannah S Seidel
Publikováno v:
eLife, Vol 4 (2015)
A cross-campus, cross-career stage and cross-disciplinary series of discussions at a large public university has produced a series of recommendations for addressing the problems confronting the biomedical research community in the US.
Externí odkaz:
https://doaj.org/article/977f332b05b245bbb249d515b2ab0389
Publikováno v:
The Journal of General Physiology
The July 2021 issue of JGP is a collection of peer-reviewed articles focused on the function and dynamic regulation of contractile systems in muscle and non-muscle cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b528abba76c5eabc450a3e782afa802
https://doi.org/10.1085/jgp.202112972
https://doi.org/10.1085/jgp.202112972
Autor:
Richard L. Moss, Wenxuan Cai, Jitandrakumar R. Patel, Rachel Heurer, Ziqing Lin, Daniel P. Fitzsimons, Zachery R. Gregorich, Ying Ge
Publikováno v:
The Journal of General Physiology
Enigma Homologue (ENH) is a Z-disc protein whose loss causes cardiomyopathy, but whose function in muscle mechanics is poorly understood. Gregorich et al. show that ENH affects tension redevelopment in mouse myocardium, possibly by altering cross-bri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9320d3f3e1aef535478a6b74bd7ccb
https://doi.org/10.1085/jgp.201812214
https://doi.org/10.1085/jgp.201812214
Autor:
Jasmine Giles, Adam Miller, Elizabeth Iverson, Richard L. Moss, Daniel P. Fitzsimons, Jitandrakumar R. Patel
Publikováno v:
The Journal of General Physiology
Knockdown of cardiac myosin binding protein C (cMyBP-C), which is the cause of many cases of hypertrophic cardiomyopathy in humans, results in left ventricular dilation, cardiac hypertrophy, and impaired ventricular function, but it is unclear whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0115491423e2dcbd579c4bcacb92878
https://doi.org/10.1085/jgp.201812238
https://doi.org/10.1085/jgp.201812238
Autor:
Richard L. Moss, Chloe Knudtsen, Jasmine Giles, Daniel P. Fitzsimons, Zander Neuville, Jitandrakumar R. Patel
Publikováno v:
The Journal of General Physiology
Giles et al. show that the phosphorylation status of cardiac myosin-binding protein-C (cMyBP-C) modulates Ca2+ activation–dependent unloaded shortening velocity of skinned myocardium. The results suggest that cMyBP-C phosphorylation regulates coope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9883012173af9fa9548950a0f086968
https://pubmed.ncbi.nlm.nih.gov/33566084
https://pubmed.ncbi.nlm.nih.gov/33566084
Autor:
Gary M. Diffee, Wenxuan Cai, Yutong Jin, Judd M. Aiken, Ziqing Lin, Liming Wei, Susan H. McKiernan, Sean J. McIlwain, Ying Ge, Zachery R. Gregorich, Richard L. Moss
Publikováno v:
Molecular & Cellular Proteomics. 17:134-145
Sarcopenia, the age-related loss of skeletal muscle mass and strength, is a significant cause of morbidity in the elderly and is a major burden on health care systems. Unfortunately, the underlying molecular mechanisms in sarcopenia remain poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac2eae2ed9162f73b5fb7eb62493e51
https://doi.org/10.1074/mcp.ra117.000124
https://doi.org/10.1074/mcp.ra117.000124
Autor:
Zhijie Wu, Wenxuan Cai, Yutong Jin, Ying Ge, Takushi Kohmoto, Ying Peng, Liming Wei, Ziqing Lin, Richard L. Moss
Publikováno v:
Analytical Chemistry. 89:4922-4930
Myosin heavy chain (MHC), the major component of the myosin motor molecule, plays an essential role in force production during muscle contraction. However, a comprehensive analysis of MHC proteoforms arising from sequence variations and post-translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7551f35fe16e803f598176964ee11ab
https://doi.org/10.1021/acs.analchem.7b00113
https://doi.org/10.1021/acs.analchem.7b00113