Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Richard L. Kingston"'
Autor:
Melissa N. Webby, Nicole Herr, Esther M. M. Bulloch, Michael Schmitz, Jeremy R. Keown, David C. Goldstone, Richard L. Kingston
Publikováno v:
Viruses, Vol 13, Iss 9, p 1737 (2021)
The paramyxoviral phosphoprotein (P protein) is the non-catalytic subunit of the viral RNA polymerase, and coordinates many of the molecular interactions required for RNA synthesis. All paramyxoviral P proteins oligomerize via a centrally located coi
Externí odkaz:
https://doaj.org/article/fb1fa7aa7a7d4673b947e3430ec172ed
Autor:
Soumeya A. Jaballah, Graham D. Bailey, Ambroise Desfosses, Jaekyung Hyun, Alok K. Mitra, Richard L. Kingston
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract During a proteolytically-driven maturation process, the orthoretroviral capsid protein (CA) assembles to form the convex shell that surrounds the viral genome. In some orthoretroviruses, including Rous Sarcoma Virus (RSV), CA carries a short
Externí odkaz:
https://doaj.org/article/736ac435609a475eba12d9102ea5d11c
Autor:
Sandesh Deshpande, Wenjuan Huo, Rinu Shrestha, Kevin Sparrow, Gary B. Evans, Lawrence D. Harris, Richard L. Kingston, Esther M. M. Bulloch
Millions of people are infected by the Dengue and Zika viruses each year, which can result in serious illness, permanent disability or death. There are currently no FDA-approved antivirals for treating infection by these viruses. Galidesivir is an ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf16530901d210e09e7934585641209b
https://doi.org/10.1101/2022.12.20.521302
https://doi.org/10.1101/2022.12.20.521302
Autor:
Naomi Fujioka, Junxuan Lu, Chengguo Xing, Katelyn M. Tessier, Sreekanth C. Narayanapillai, Qi Hu, Ramzi G. Salloum, Dorothy K. Hatsukami, Stephen S. Hecht, Yi Wang, Pramod Upadhyaya, Lori S Strayer, Richard L. Kingston
Publikováno v:
Cancer Prev Res (Phila)
Tobacco smoking is the primary risk factor for lung cancer, driven by the addictive nature of nicotine and the indisputable carcinogenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) as well as other compounds. The integration of lung ca
Publikováno v:
Biomolecular NMR Assignments. 13:195-199
Menangle virus is a bat-borne paramyxovirus with zoonotic potential. The single-stranded RNA genome of the virus is encapsidated in a helical nucleocapsid which is the template for both transcription and genome replication. Each of these operations i
Autor:
William R. Troy, Thomas G. Osimitz, Pamela Dalton, Mark J. Utell, Steve Horenziak, Farah K. Ahmed, Madhuri Singal, Rachel S. Herz, Mary B. Johnson, J. R. Wells, Steven E. Prawer, Shan Yin, Richard L. Kingston
Publikováno v:
Inhalation Toxicology. 31:12-24
Seventy-one percent of US households purchase air care products. Air care products span a diverse range of forms, including scented aerosol sprays, pump sprays, diffusers, gels, candles, and plug-ins. These products are used to eliminate indoor malod
Publikováno v:
Virus Evolution
The phosphoprotein gene of the paramyxoviruses encodes multiple protein products. The P, V, and W proteins are generated by transcriptional slippage. This process results in the insertion of non-templated guanosine nucleosides into the mRNA at a cons
Autor:
Richard L. Kingston, Tyler Daniels, Tengfei Bian, Yuzhi Wang, Pedro Corral, Junxuan Lu, Zhiguang Huo, Chengguo Xing, Andrew C. Liu, Jordy F. Botello, Edward Johnston, Ramzi G. Salloum
Publikováno v:
Nutrients, Vol 12, Iss 3044, p 3044 (2020)
Nutrients
Nutrients
Kava beverages are typically prepared from the root of Piper methysticum. They have been consumed among Pacific Islanders for centuries. Kava extract preparations were once used as herbal drugs to treat anxiety in Europe. Kava is also marketed as a d
Autor:
Igor Koturbash, Mahmoud A. ElSohly, Bill J. Gurley, Charles R. Yates, Ikhlas A. Khan, Larry A. Walker, Richard L. Kingston
Publikováno v:
Journal of dietary supplements. 17(5)
The proliferation in the last few years of cannabidiol (CBD)-containing products in the U.S. markets has been greatly accelerated by changes in the regulatory environment, and by perceptions of their health benefits and presumed safety. The result ha
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1006717 (2020)
PLoS Computational Biology
PLoS Computational Biology
Transcription elongation can be modelled as a three step process, involving polymerase translocation, NTP binding, and nucleotide incorporation into the nascent mRNA. This cycle of events can be simulated at the single-molecule level as a continuous-