Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Richard L. Cerruti"'
Autor:
Richard L. Cerruti, R B Belshe, Percy S. Manchand, Iain S. Sim, Elizabeth Keech, Joseph A. Martin, Edward V. Connell, John Herbert Merrett, Hill Christopher Huw
Publikováno v:
Journal of Medicinal Chemistry. 33:1992-1995
The hydroxy metabolites of rimantadine (3-5) were synthesized and compared to amantadine (1) and rimantadine (2) for their ability to inhibit the replication of influenza viruses in vitro. All three metabolites were inhibitory to wild-type influenza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa60daf956cafc6711d9bb99eeadb66
https://doi.org/10.1021/jm00169a029
https://doi.org/10.1021/jm00169a029
Publikováno v:
Antiviral Research. 5:217-223
Hairless mice were infected intracutaneously with HSV-1 and treated with rHuIFN-alpha A/D, a recombinant DNA-derived hybrid human interferon-alpha that is active on mouse cells in vitro and in vivo. When given alone (1 or 2 X 10(5) units/dose) at tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7c38d53e80aac58a4460552acddc3d
https://doi.org/10.1016/s0166-3542(85)80031-0
https://doi.org/10.1016/s0166-3542(85)80031-0
Autor:
Richard L. Cerruti, Iain S. Sim
Publikováno v:
Antiviral Research. 8:209-221
The antiviral properties of 2 recombinant DNA-produced interferons, a human hybrid interferon alpha that is active in mice and a murine interferon gamma, were examined in the treatment of mice infected with encephalomyocarditis virus. A single dose o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218e41fc7161f7c14b0dbda25f8e32ee
https://doi.org/10.1016/0166-3542(87)90075-1
https://doi.org/10.1016/0166-3542(87)90075-1
Resistance of influenza A virus to amantadine and rimantadine: results of one decade of surveillance
Publikováno v:
The Journal of infectious diseases. 159(3)
All clinical isolates of influenza A viruses from patients in Huntington, West Virginia, during the decade 1978-1988 were tested, and 65 of 65 H1N1 and 176 of 181 H3N2 viruses were susceptible to the antiviral action of amantadine and rimantadine. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a8213cf3c0a9dc5fac1b1dce671210
https://pubmed.ncbi.nlm.nih.gov/2915166
https://pubmed.ncbi.nlm.nih.gov/2915166
Publikováno v:
Journal of Infectious Diseases; 1989, Vol. 159 Issue 3, p430-435, 6p