Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Richard L. Benton"'
Autor:
Scott A. Myers, William H. DeVries, Kariena R. Andres, Mark J. Gruenthal, Richard L. Benton, James B. Hoying, Theo Hagg, Scott R. Whittemore
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 1, Pp 21-34 (2011)
Recent data have implicated thrombospondin-1 (TSP-1) signaling in the acute neuropathological events that occur in microvascular endothelial cells (ECs) following spinal cord injury (SCI) (Benton et al., 2008b). We hypothesized that deletion of TSP-1
Externí odkaz:
https://doaj.org/article/e896c9b537224cd988d7634513054302
Publikováno v:
ASN Neuro, Vol 1 (2009)
Microvascular dysfunction, loss of vascular support, ischaemia and sub-acute vascular instability in surviving blood vessels contribute to secondary injury following SCI (spinal cord injury). Neither the precise temporal profile of the cellular dynam
Externí odkaz:
https://doaj.org/article/b42cfd3ec5b94a3ca8a44722306a48aa
Publikováno v:
Metabolic Brain Disease. 30:411-426
Traumatic brain injury (TBI) is accompanied with enhanced matrix metalloproteinase-9 (MMP-9) activity and elevated levels of plasma fibrinogen (Fg), which is a known inflammatory agent. Activation of MMP-9 and increase in blood content of Fg (i.e. hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d9e2a1d59b9cef2d568c7785a8a5eb
https://doi.org/10.1007/s11011-014-9550-3
https://doi.org/10.1007/s11011-014-9550-3
Autor:
Kenneth E. Miller, Ruben Schechter, Richard L. Benton, Kristin M. Edwards, Travis S. Lam, John C. Balbás, Richard M. Kriebel
Publikováno v:
Pain Research and Treatment, Vol 2012 (2012)
Pain Research and Treatment
Pain Research and Treatment
Following inflammation, primary sensory neurons in the dorsal root ganglion (DRG) alter the production of several proteins. Most DRG neurons are glutamatergic, using glutaminase as the enzyme for glutamate production, but little is known about glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ee3a1b913e06a0a09c5c3dda8ff4a4
https://doi.org/10.1155/2012/414697
https://doi.org/10.1155/2012/414697
Publikováno v:
Current Neurovascular Research. 6:124-131
Acute loss of spinal cord vascularity followed by an endogenous adaptive angiogenic response with concomitant microvascular dysfunction is a hallmark of traumatic spinal cord injury (SCI). Recently, the potent vasoactive factor vascular endothelial g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f909af35bb0288eecf922fd83b5be02
https://doi.org/10.2174/156720209788185678
https://doi.org/10.2174/156720209788185678
Publikováno v:
Journal of Neurotrauma. 23:479-495
Stem cells hold great promise for therapeutic repair after spinal cord injury (SCI). This review compares the current experimental approaches taken towards a stem cell-based therapy for SCI. It critically evaluates stem cell sources, injury paradigms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cf4baa763c09abb2fd79929bf2806f
https://doi.org/10.1089/neu.2006.23.479
https://doi.org/10.1089/neu.2006.23.479
Autor:
Scott R. Whittemore, Carmen Hernández, Jorge D. Miranda, Johnny D. Figueroa, Aranza I. Torrado, Cristina M. Ortiz, Richard L. Benton, Ixane Velázquez, David S.K. Magnuson, Juan J. Diaz
Publikováno v:
Journal of Neuroscience Research. 84:1438-1451
Functional impairment after spinal cord injury (SCI) is partially attributed to neuronal cell death, with further degeneration caused by the accompanying apoptosis of myelin-forming oligodendrocytes. The Eph receptor protein tyrosine kinase family an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36569fb7bc2aaeff3336c7434ac63db
https://doi.org/10.1002/jnr.21048
https://doi.org/10.1002/jnr.21048
Autor:
Scott R. Whittemore, Russell M. Howard, Richard L. Benton, John P. Woock, Gaby Enzmann, Pantelis Tsoulfas
Publikováno v:
Experimental Neurology. 195:293-304
Bone morphogenetic proteins (BMPs) are a large class of secreted factors, which serve as modulators of development in multiple organ systems, including the CNS. Studies investigating the potential of stem cell transplantation for restoration of funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff3c078d2f98df3881c37ab2faf3a2c
https://doi.org/10.1016/j.expneurol.2005.04.021
https://doi.org/10.1016/j.expneurol.2005.04.021
Autor:
Richard L. Benton, Scott R. Whittemore
Publikováno v:
Neurochemical Research. 28:1693-1703
Vascular endothelial growth factor (VEGF) demonstrates potent and well-characterized effects on endothelial cytoprotection and angiogenesis. In an attempt to preserve spinal microvasculature and prolong the endogenous neovascular response observed tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0de6f12ae979f7c1dcaab3dcda3f3e6
https://doi.org/10.1023/a:1026013106016
https://doi.org/10.1023/a:1026013106016
The role of the inflammatory agent fibrinogen (Fg) in increased pial venular permeability has been shown previously. It was suggested that an activation of matrix metalloproteinase-9 (MMP-9) is involved in Fg-induced enhanced transcytosis through end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081d5d899fd2cac33fc7a8bc01efa1b
https://europepmc.org/articles/PMC4020992/
https://europepmc.org/articles/PMC4020992/
