Zobrazeno 1 - 10 of 209 pro vyhledávání: '"Richard L Shapiro"'
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Akademický článek
Intra- and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma.
Autor: Molly Yancovitz, Adam Litterman, Joanne Yoon, Elise Ng, Richard L Shapiro, Russell S Berman, Anna C Pavlick, Farbod Darvishian, Paul Christos, Madhu Mazumdar, Iman Osman, David Polsky
Publikováno v: PLoS ONE, Vol 7, Iss 1, p e29336 (2012)
The rationale for using small molecule inhibitors of oncogenic proteins as cancer therapies depends, at least in part, on the assumption that metastatic tumors are primarily clonal with respect to mutant oncogene. With the emergence of BRAF(V600E) as
Externí odkaz: https://doaj.org/article/b5525cc056164b37b0b637ca0759c512
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3
Akademický článek
No Cancer Occurrences in 10-year Follow-up after Prophylactic Nipple-sparing Mastectomy
Autor: Carter J. Boyd, MD, MBA, Jonathan M. Bekisz, MD, MSci, Sruthi Ramesh, BS, Kshipra Hemal, MD, Amber A. Guth, MD, Deborah M. Axelrod, MD, Richard L. Shapiro, MD, Karen Hiotis, MD, Freya R. Schnabel, MD, Mihye Choi, MD, Nolan S. Karp, MD
Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 6, p e5087 (2023)
Background:. Prophylactic nipple-sparing mastectomies (NSM) have become increasingly common, although there is little long-term data on its efficacy in prevention of breast cancer. The objective of this study was to assess the incidence of breast can
Externí odkaz: https://doaj.org/article/878543ee65f1427093df0fb212b1660f
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4
Data from Melanoma MicroRNA Signature Predicts Post-Recurrence Survival
Autor: Eva Hernando, Iman Osman, Anna C. Pavlick, Richard L. Shapiro, Russell S. Berman, Farbod Darvishian, Douglas Hanniford, Avital Gaziel, Jan Zakrzewski, Amy E. Rose, Ilana Belitskaya-Lévy, Miguel F. Segura
Purpose: To identify a melanoma microRNA (miRNA) expression signature that is predictive of outcome and then evaluate its potential to improve risk stratification when added to the standard-of-care staging criteria.Experimental Design: Total RNA was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333f15fc0806382d3bc8b3c1731b1979
https://doi.org/10.1158/1078-0432.c.6518724.v1
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7
Data from The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis
Autor: Tomas Kirchhoff, Iman Osman, Michelle Krogsgaard, Russell S. Berman, Richard L. Shapiro, Esther Kazlow, Artur Romanchuk, Karolina Malecek, Anuj Bapodra, Justin Rendleman, Carlos N. Martinez, Matjaz Vogelsang
Purpose: The identification of personalized germline markers with biologic relevance for the prediction of cutaneous melanoma prognosis is highly demanded but to date, it has been largely unsuccessful. As melanoma progression is controlled by host im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0390c162431e9257418777ff27436402
https://doi.org/10.1158/1078-0432.c.6523388.v1
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8
Data from Identification of a Novel Pathogenic Germline KDR Variant in Melanoma
Autor: Iman Osman, Tomas Kirchhoff, Judy Zhong, Anna Pavlick, Richard L. Shapiro, Melissa A. Wilson, Eric M. Robinson, Kevin P. Lui, Naima Ismaili, Sung W. Han, Matjaz Vogelsang, Keith M. Giles, Amel Salhi, Ines P. Silva
Purpose: The application of pan-cancer next-generation sequencing panels in the clinical setting has facilitated the identification of low frequency somatic mutations and the testing of new therapies in solid tumors using the "basket trial" scheme. H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa81c6d531761df1e453fbb23ae8f8f
https://doi.org/10.1158/1078-0432.c.6523320
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