Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Richard L Ornberg"'
Autor:
Denis Forster, Steven L. Settle, Dennis P. Riley, K. Bruce Thurmond, Kishore Udipi, Richard L. Ornberg
Publikováno v:
Journal of Biomedical Materials Research. 51:549-560
The healing response to implanted biomedical materials involves varying degrees and stages of inflammation and healing which in some cases leads to device failure. In this article, we describe synthetic methods and in vivo results of a novel surface
Autor:
Richard L. Ornberg, Frances M. Platt, Philip G. Woodman, Terry D. Butters, Gabrielle R. Neises
Publikováno v:
Biology of the Cell. 89:123-131
The imino sugar N-butyldeoxynojirimycin inhibits the N-linked oligosaccharide processing enzymes α-glucosidases I and II, and the ceramide specific glucosyltransferase which catalyses the first step in glucosphingolipid biosynthesis. We have studied
Publikováno v:
Nature Methods. 2:79-81
Western or immunoblotting analysis of protein expression in cells and tissues has been the major analytical tool for assessing molecular biological functions in basic cell biological research, pathology and drug discovery and development. With the ra
Autor:
Karen Seibert, Daniela Salvemini, Richard L. Ornberg, Susan M. Colburn, Peter C. Isakson, Ben S. Zweifel, Jaime L. Masferrer
Publikováno v:
American Journal of Therapeutics. 2:607-610
Prostaglandins (PGs) can be synthetized via two isoforms of cyclooxygenase (COX). COX-1 is constitutively expressed in normal tissues, and its activity represent the normal physiological output of PGs. In inflammatory states, the newly discovered COX
Publikováno v:
Annals of Plastic Surgery. 30:398-404
The extrinsic pathway of coagulation is initiated when tissue factor complexes with factor VII. A naturally occurring protein inhibitor of this complex, tissue factor pathway inhibitor (TFPI), has recently been isolated and the cDNA coding for this p
Autor:
Richard L, Ornberg, Hongjian, Liu
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 374
Our understanding of the level and distribution of gene and protein expression in cells is a key component of modern cell biological and medical research. Detecting intracellular proteins with labeled antibodies or genes with labeled oligonucleotide
Autor:
Hongjian Liu, Richard L. Ornberg
Our understanding of the level and distribution of gene and protein expression in cells is a key component of modern cell biological and medical research. Detecting intracellular proteins with labeled antibodies or genes with labeled oligonucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0989268d979eb5898e44a7445fb10735
https://doi.org/10.1385/1-59745-369-2:3
https://doi.org/10.1385/1-59745-369-2:3
Autor:
Richard L. Ornberg, Kathleen M. Leahy, Yanli Zhu, Jane R. Connor, Martin B. Wax, Yu Wang, Jeffrey M. Gidday
Publikováno v:
Experimental eye research. 79(1)
To evaluate the neuroprotective potential of drug candidates to treat human glaucoma, a short-term rodent model of retinal ganglion cell death was employed. Transient ischemia applied to the rodent retina, with subsequent reperfusion for 1-4 weeks, p
Autor:
Amy L. Jones, Kevin S. Chinn, Andrew R. Lisowski, Medora M. Hardy, Eric A.G. Blomme, Alan C. Opsahl, Catherine S. Tripp, Janet M. Harmon, Richard L. Ornberg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 304(3)
The cyclooxygenase isoforms, COX-1 and COX-2, are the rate limiting enzymes in the biosynthesis of prostaglandin E(2), a major prostaglandin involved in epidermal homeostasis and repair. Epidermal injury results in transient hyperplasia and induction
Publikováno v:
Cancer research. 62(22)
Both nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase (COX) 2-selective inhibitors such as celecoxib are being reported as having potent anticancer activity in laboratory models. Several reports have suggested that the mechanism of ac