Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Richard L Gallo"'
Autor:
Alan M O'Neill, Kate A Worthing, Nikhil Kulkarni, Fengwu Li, Teruaki Nakatsuji, Dominic McGrosso, Robert H Mills, Gayathri Kalla, Joyce Y Cheng, Jacqueline M Norris, Kit Pogliano, Joe Pogliano, David J Gonzalez, Richard L Gallo
Publikováno v:
eLife, Vol 10 (2021)
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important emerging zoonotic pathogen that causes severe skin infections. To combat infections from drug-resistant bacteria, the transplantation of commensal antimicrobial bacteria as
Externí odkaz:
https://doaj.org/article/8239653fab1c46dc8610832c2aa22e68
Autor:
Kun Tan, Samantha H Jones, Blue B Lake, Jennifer N Chousal, Eleen Y Shum, Lingjuan Zhang, Song Chen, Abhishek Sohni, Shivam Pandya, Richard L Gallo, Kun Zhang, Heidi Cook-Andersen, Miles F Wilkinson
Publikováno v:
eLife, Vol 9 (2020)
The UPF3B-dependent branch of the nonsense-mediated RNA decay (NMD) pathway is critical for human cognition. Here, we examined the role of UPF3B in the olfactory system. Single-cell RNA-sequencing (scRNA-seq) analysis demonstrated considerable hetero
Externí odkaz:
https://doaj.org/article/8a0c1bf4ffd94ebebb77c22183768b09
Autor:
Alon Peled, Ofer Sarig, Liat Samuelov, Marta Bertolini, Limor Ziv, Daphna Weissglas-Volkov, Marina Eskin-Schwartz, Christopher A Adase, Natalia Malchin, Ron Bochner, Gilad Fainberg, Ilan Goldberg, Koji Sugawara, Avital Baniel, Daisuke Tsuruta, Chen Luxenburg, Noam Adir, Olivier Duverger, Maria Morasso, Stavit Shalev, Richard L Gallo, Noam Shomron, Ralf Paus, Eli Sprecher
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006369 (2016)
Despite recent advances in our understanding of the pathogenesis of ectodermal dysplasias (EDs), the molecular basis of many of these disorders remains unknown. In the present study, we aimed at elucidating the genetic basis of a new form of ED featu
Externí odkaz:
https://doaj.org/article/2a310f48642d4138a48fbddd5896a7f3
Autor:
Dawn Z Eichenfield, Ty Dale Troutman, Verena M Link, Michael T Lam, Han Cho, David Gosselin, Nathanael J Spann, Hanna P Lesch, Jenhan Tao, Jun Muto, Richard L Gallo, Ronald M Evans, Christopher K Glass
Publikováno v:
eLife, Vol 5 (2016)
Although macrophages can be polarized to distinct phenotypes in vitro with individual ligands, in vivo they encounter multiple signals that control their varied functions in homeostasis, immunity, and disease. Here, we identify roles of Rev-erb nucle
Externí odkaz:
https://doaj.org/article/9179063de878401aa231e8f29651e197
Autor:
Filipe Carvalho, Magda L Atilano, Rita Pombinho, Gonçalo Covas, Richard L Gallo, Sérgio R Filipe, Sandra Sousa, Didier Cabanes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004919 (2015)
Listeria monocytogenes is an opportunistic Gram-positive bacterial pathogen responsible for listeriosis, a human foodborne disease. Its cell wall is densely decorated with wall teichoic acids (WTAs), a class of anionic glycopolymers that play key rol
Externí odkaz:
https://doaj.org/article/df7c24b2fd2c468d8c8b8d8bc20cd231
Autor:
Tatsuya Dokoshi, Yang Chen, Kellen J. Cavagnero, Gibraan Rahman, Daniel Hakim, Samantha Brinton, Hana Schwarz, Elizabeth A. Brown, Alan O’Neill, Yoshiyuki Nakamura, Fengwu Li, Nita H. Salzman, Rob Knight, Richard L. Gallo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The composition of the microbial community in the intestine may influence the functions of distant organs such as the brain, lung, and skin. These microbes can promote disease or have beneficial functions, leading to the hypothesis that micr
Externí odkaz:
https://doaj.org/article/4267502e50f84cdea19b99fb89c67bd3
Autor:
Morgan A Pence, Nina M Haste, Hiruy S Meharena, Joshua Olson, Richard L Gallo, Victor Nizet, Sascha A Kristian
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136605 (2015)
BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S. aureus Newman for susceptibility to cathelicidin antimicrobial peptide, we discovered BlaI as
Externí odkaz:
https://doaj.org/article/eaf0b834087e49beb6fc54aed36b44d3
Autor:
Paula E Beaumont, Brian McHugh, Emily Gwyer Findlay, Annie Mackellar, Karen J Mackenzie, Richard L Gallo, John R W Govan, A John Simpson, Donald J Davidson
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99029 (2014)
Cathelicidins are multifunctional cationic host-defence peptides (CHDP; also known as antimicrobial peptides) and an important component of innate host defence against infection. In addition to microbicidal potential, these peptides have properties w
Externí odkaz:
https://doaj.org/article/0fbf999318614893be87e3f90c106aae
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72421 (2013)
The release of endogenous molecules from the skin after injury has been proposed to influence inflammation. Recent studies have found that pro-inflammatory signals can be generated by damaged endogenous self-RNA, and this event is detected by TLR3. C
Externí odkaz:
https://doaj.org/article/e6294350c8674e6e8b63843c84646f3a
Autor:
Muya Shu, Yanhan Wang, Jinghua Yu, Sherwin Kuo, Alvin Coda, Yong Jiang, Richard L Gallo, Chun-Ming Huang
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55380 (2013)
Bacterial interference creates an ecological competition between commensal and pathogenic bacteria. Through fermentation of milk with gut-friendly bacteria, yogurt is an excellent aid to balance the bacteriological ecosystem in the human intestine. H
Externí odkaz:
https://doaj.org/article/656b8a29f7fe44ddab3b1a1228afda24