Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Richard L Dunbar"'
Autor:
Richard L. Dunbar, Daniel Gaudet, Michael Davidson, Martin Rensfeldt, Hong Yang, Catarina Nilsson, Mats Kvarnström, Jan Oscarsson
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-14 (2020)
Abstract Background Omega-3 fatty acids (OM3-FAs) are recommended with a low-fat diet for severe hypertriglyceridemia (SHTG), to reduce triglycerides and acute pancreatitis (AP) risk. A low-fat diet may reduce pancreatic lipase secretion, which is re
Externí odkaz:
https://doaj.org/article/5b68c5eb56e5404db2b385287af83975
Autor:
Masako Ueda, Anna Wolska, Frances M. Burke, Maria Escobar, Laura Walters, Dusanka Lalic, Robert A. Hegele, Alan T. Remaley, Daniel J. Rader, Richard L. Dunbar
Publikováno v:
Case Reports in Endocrinology, Vol 2020 (2020)
Background. Among many causes of hypertriglyceridemia (HTG), familial chylomicronemia syndrome (FCS) is a rare monogenic disorder that manifests as severe HTG and acute pancreatitis. Among the known causal genes for FCS, mutations in APOC2 only accou
Externí odkaz:
https://doaj.org/article/70dc5cc48f1c48558a28209aa605a187
Autor:
John S. Millar, Michael E. Lassman, Tiffany Thomas, Rajasekhar Ramakrishnan, Patricia Jumes, Richard L. Dunbar, Emil M. deGoma, Amanda L. Baer, Wahida Karmally, Daniel S. Donovan, Hashmi Rafeek, John A. Wagner, Stephen Holleran, Joseph Obunike, Yang Liu, Soumia Aoujil, Taylor Standiford, David E. Gutstein, Henry N. Ginsberg, Daniel J. Rader, Gissette Reyes-Soffer
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1214-1220 (2017)
Cholesteryl ester transfer protein (CETP) mediates the transfer of HDL cholesteryl esters for triglyceride (TG) in VLDL/LDL. CETP inhibition, with anacetrapib, increases HDL-cholesterol, reduces LDL-cholesterol, and lowers TG levels. This study descr
Externí odkaz:
https://doaj.org/article/519f42374d614106b1158dd25fc71604
Autor:
Marina Cuchel, Anna C. Raper, Donna M. Conlon, Daniel A. Pryma, Richard H. Freifelder, Rahul Poria, Debra Cromley, Xiaoyu Li, Richard L. Dunbar, Benjamin French, Liming Qu, William Farver, Ching-Chiang Su, Sissel Lund-Katz, Amanda Baer, Giacomo Ruotolo, Peter Akerblad, Carol S. Ryan, Lan Xiao, Todd G. Kirchgessner, John S. Millar, Jeffrey T. Billheimer, Daniel J. Rader
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 752-762 (2017)
Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis. We developed a novel method using 3H-cholesterol nanoparticles to selectively
Externí odkaz:
https://doaj.org/article/50852041bbb149b0ab71cadc9ddee278
Autor:
Richard L. Dunbar, Harsh Goel, Sony Tuteja, Wen-Liang Song, Grace Nathanson, Zeeshan Babar, Dusanka Lalic, Joel M. Gelfand, Daniel J. Rader, Gary L. Grove
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 783-797 (2017)
Though cardioprotective, niacin monotherapy is limited by unpleasant cutaneous symptoms mimicking dermatitis: niacin-associated skin toxicity (NASTy). Niacin is prototypical of several emerging drugs suffering off-target rubefacient properties whereb
Externí odkaz:
https://doaj.org/article/a6e5ce3a9f6247d9b5aaf707a782ce65
Autor:
Sony Tuteja, Liming Qu, Marijana Vujkovic, Richard L. Dunbar, Jinbo Chen, Stephanie DerOhannessian, Daniel J. Rader
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 19 (2018)
Background Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether the
Externí odkaz:
https://doaj.org/article/a067c6e84cad456a93baeea5459eaea2
Autor:
Catarina Nilsson, Daniel Gaudet, Martin Rensfeldt, Jan Oscarsson, Mats Kvarnström, Richard L. Dunbar, Michael H. Davidson, Hong Yang
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-14 (2020)
Lipids in Health and Disease
Lipids in Health and Disease
Background Omega-3 fatty acids (OM3-FAs) are recommended with a low-fat diet for severe hypertriglyceridemia (SHTG), to reduce triglycerides and acute pancreatitis (AP) risk. A low-fat diet may reduce pancreatic lipase secretion, which is required to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5c04457baaeed0a94c685b6ec744ec
http://link.springer.com/article/10.1186/s12944-020-01295-7
http://link.springer.com/article/10.1186/s12944-020-01295-7
Publikováno v:
Acta Diabetologica. 57:809-818
Lowering postprandial lipemia may mitigate cardiovascular risk in patients with diabetic dyslipidemia. This study was aimed to investigate whether saroglitazar suppresses postprandial lipemia in patients with diabetes and dyslipidemia. This was a 12-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a001ffb58bf1f5d418b28be441354f50
https://doi.org/10.1007/s00592-020-01487-8
https://doi.org/10.1007/s00592-020-01487-8
Autor:
Aurelie Bouzelmat, Hayes Dansky, Richard L. Dunbar, Daniel A. Gipe, Robert Pordy, Scott Mellis, Poulabi Banerjee, Kuo Chen Chan, Sara Hamon, Zahid Ahmad, William J. Sasiela
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Hypertriglyceridemia is associated with increased cardiovascular risk and may be caused by impaired lipoprotein clearance. Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprot
Background: Hypertriglyceridemia is associated with increased cardiovascular risk and may be caused by impaired lipoprotein clearance. Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ea5de88d5f8cc91b3be7a90ac7adfe
http://europepmc.org/articles/PMC6686956
http://europepmc.org/articles/PMC6686956
Autor:
Richard L Dunbar, Daniel J. Rader, Anna Wolska, Masako Ueda, Maureen Sampson, Frances M. Burke, Alan T. Remaley
Publikováno v:
Journal of the Endocrine Society
Background: Hypertriglyceridemia (HTG) is common; however, pseudo-HTG due to high glycerol in glycerol kinase deficiency (GKD, MIM: 307030) is a rare cause of HTG that need to be delineated for appropriate management. GKD is an X-linked recessive dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be6ea47fbfc345e9f7f11bcfd8b784a
https://doi.org/10.1210/jendso/bvaa046.075
https://doi.org/10.1210/jendso/bvaa046.075