Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Richard L, Sidman"'
Autor:
Joseph D Butner, Geoffrey V Martin, Zhihui Wang, Bruna Corradetti, Mauro Ferrari, Nestor Esnaola, Caroline Chung, David S Hong, James W Welsh, Naomi Hasegawa, Elizabeth A Mittendorf, Steven A Curley, Shu-Hsia Chen, Ping-Ying Pan, Steven K Libutti, Shridar Ganesan, Richard L Sidman, Renata Pasqualini, Wadih Arap, Eugene J Koay, Vittorio Cristini
Publikováno v:
eLife, Vol 10 (2021)
Background: Checkpoint inhibitor therapy of cancer has led to markedly improved survival of a subset of patients in multiple solid malignant tumor types, yet the factors driving these clinical responses or lack thereof are not known. We have develope
Externí odkaz:
https://doaj.org/article/fb8dc9b236644627993affff85ba8824
Autor:
Fernanda I Staquicini, Amin Hajitou, Wouter HP Driessen, Bettina Proneth, Marina Cardó-Vila, Daniela I Staquicini, Christopher Markosian, Maria Hoh, Mauro Cortez, Anupama Hooda-Nehra, Mohammed Jaloudi, Israel T Silva, Jaqueline Buttura, Diana N Nunes, Emmanuel Dias-Neto, Bedrich Eckhardt, Javier Ruiz-Ramírez, Prashant Dogra, Zhihui Wang, Vittorio Cristini, Martin Trepel, Robin Anderson, Richard L Sidman, Juri G Gelovani, Massimo Cristofanilli, Gabriel N Hortobagyi, Zaver M Bhujwalla, Stephen K Burley, Wadih Arap, Renata Pasqualini
Publikováno v:
eLife, Vol 10 (2021)
Triple-negative breast cancer (TNBC) is an aggressive tumor with limited treatment options and poor prognosis. We applied the in vivo phage display technology to isolate peptides homing to the immunosuppressive cellular microenvironment of TNBC as a
Externí odkaz:
https://doaj.org/article/2b69063fcd2842da978005193781ce00
Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction
Autor:
Jianxue Li, Evan Y. Snyder, Fenny H.F. Tang, Renata Pasqualini, Wadih Arap, Richard L. Sidman
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Posttranslational glutamylation/deglutamylation balance in tubulins influences dendritic maturation and neuronal survival of cerebellar Purkinje neurons (PNs). PNs and some additional neuronal types degenerate in several spontaneous, independently oc
Externí odkaz:
https://doaj.org/article/ae2da415ddf04f47b7b57947e2315661
Autor:
Andre A Teixeira, Serena Marchiò, Emmanuel Dias‐Neto, Diana N Nunes, Israel T da Silva, Bryce Chackerian, Marc Barry, Richard C Lauer, Ricardo J Giordano, Richard L Sidman, Cosette M Wheeler, Webster K Cavenee, Renata Pasqualini, Wadih Arap
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 10, Pp 1327-1330 (2017)
Graphical Abstract The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer ini
Externí odkaz:
https://doaj.org/article/8d221eac6f144f378b13373e38c5f65b
Autor:
Daniela I. Staquicini, Roberto Rangel, Liliana Guzman-Rojas, Fernanda I. Staquicini, Andrey S. Dobroff, Christy A. Tarleton, Michelle A. Ozbun, Mikhail G. Kolonin, Juri G. Gelovani, Serena Marchiò, Richard L. Sidman, Katherine A. Hajjar, Wadih Arap, Renata Pasqualini
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cytoskeletal-associated proteins play an active role in coordinating the adhesion and migration machinery in cancer progression. To identify functional protein networks and potential inhibitors, we screened an internalizing phage (iPhage) di
Externí odkaz:
https://doaj.org/article/5856840a50164afb9f65b36ea3d9f06a
Spatial and temporal dynamics of HDACs class IIa following mild traumatic brain injury in adult rats
Autor:
Swatabdi R. Kamal, Shreya Potukutchi, David J. Gelovani, Robin E. Bonomi, Srinivasu Kallakuri, John M. Cavanaugh, Thomas Mangner, Alana Conti, Ren-Shyan Liu, Renata Pasqualini, Wadih Arap, Richard L. Sidman, Shane A. Perrine, Juri G. Gelovani
Publikováno v:
Molecular Psychiatry. 27:1683-1693
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2b8922967a0b0bc2e192241d82c512
https://doi.org/10.1038/s41380-021-01369-7
https://doi.org/10.1038/s41380-021-01369-7
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 6, Pp 592-594 (2016)
Abstract Neurovascular disorders are difficult to treat due to the blood–brain barrier (BBB), which prevents delivery of most drugs from the blood into the brain. Gene therapy can potentially overcome this barrier, but classical vectors are neither
Externí odkaz:
https://doaj.org/article/ad9b36cec15a47879f662fbb001e7f4a
Autor:
Bipul R. Acharya, Dritan Agalliu, V.A. Alexandrescu, Zakaria Almuwaqqat, Rheure Alves-Lopes, Ken Arai, Wadih Arap, Victoria L. Bautch, Lisa M. Becker, Michelle P. Bendeck, Jan Walter Benjamins, Saptarshi Biswas, E. Boesmans, Livia L. Camargo, Peter Carmeliet, Munir Chaudhuri, Nicholas W. Chavkin, Ondine Cleaver, Clément Cochain, Michael S. Conte, Azzurra Cottarelli, Christie L. Crandall, Anne Cuypers, Andreas Daiber, Alan Dardik, Jui M. Dave, J.O. Defraigne, Wenjun Deng, Robert J. DeStefano, Devinder Dhindsa, Danny J. Eapen, Anne Eichmann, Christian El Amm, Omotayo Eluwole, Christian Faaborg-Andersen, Steven A. Fisher, Zorina S. Galis, Guillermo García-Cardeña, Xin Geng, Michael A. Gimbrone, Luis Gonzalez, Daniel M. Greif, Xiaowu Gu, Shuzhen Guo, Tara L. Haas, Omar Hahad, Pim van der Harst, Peter K. Henke, Karen K. Hirschi, C. Holemans, Gonçalo Hora de Carvalho, Song Hu, Jay D. Humphrey, Shabatun J. Islam, Xinguo Jiang, Luis Eduardo Juarez-Orozco, Angelos D. Karagiannis, Anita Kaw, Kaveeta Kaw, Fatemeh Kazemzadeh, A. Kerzmann, Alexander S. Kim, Ageliki Laina, Eva K. Lee, Jinyu Li, Wenlu Li, Chien-Jung Lin, Xiaolei Liu, Eng H. Lo, Josephine Lok, Mark W. Majesky, Ziad Mallat, Muzi J. Maseko, Dianna M. Milewicz, Amanda L. Mohabeer, Augusto C. Montezano, Giorgio Mottola, Thomas Münzel, Daniel D. Myers, Karla B. Neves, Mark R. Nicolls, MingMing Ning, Andrea T. Obi, Guillermo Oliver, Renata Pasqualini, Alessandra Pasut, Alexandra Pislaru, Aleksander S. Popel, Raymundo A. Quintana, Arshed A. Quyyumi, Francisco J. Rios, Stanley G. Rockson, Martina Rudnicki, Junichi Saito, Charles D. Searles, Timothy W. Secomb, Cristina M. Sena, Richard L. Sidman, Federico Silva-Palacios, Tracey L. Smith, Suman Sood, Laurence S. Sperling, R. Sathish Srinivasan, Kimon Stamatelopoulos, Konstantinos Stellos, Naidi Sun, Wen Tian, Rhian M. Touyz, Nikolaos Ι. Vlachogiannis, Jessica E. Wagenseil, Thomas W. Wakefield, Charlotte R. Wayne, Changhong Xing, Ming Wai Yeung, Yu Zhang, Chen Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368f68174074e2f57417a7dd878baa13
https://doi.org/10.1016/b978-0-12-822546-2.01002-9
https://doi.org/10.1016/b978-0-12-822546-2.01002-9
Autor:
Bruna Corradetti, James W. Welsh, Steven A. Curley, Caroline Chung, Ping-Ying Pan, Elizabeth A. Mittendorf, Zhihui Wang, Richard L. Sidman, Vittorio Cristini, Shridar Ganesan, Naomi Hasegawa, Renata Pasqualini, Geoffrey V. Martin, Joseph D. Butner, Nestor F. Esnaola, Wadih Arap, Eugene J. Koay, Mauro Ferrari, Shu-Hsia Chen, David S. Hong, Steven K. Libutti
Publikováno v:
Elife
eLife
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
Background:Checkpoint inhibitor therapy of cancer has led to markedly improved survival of a subset of patients in multiple solid malignant tumor types, yet the factors driving these clinical responses or lack thereof are not known. We have developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad93b92ba2a8ba0cf330c7fb26204721
https://doi.org/10.7554/elife.70130
https://doi.org/10.7554/elife.70130