Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Richard L, Friedman"'
Autor:
Christopher J. Alteri, Nora Rios-Sarabia, Miguel A. De la Cruz, Jorge A. González-y-Merchand, Jorge Soria-Bustos, Carmen Maldonado-Bernal, María L. Cedillo, Jorge A. Yáñez-Santos, Ygnacio Martínez-Laguna, Javier Torres, Richard L. Friedman, Jorge A. Girón, Miguel A. Ares
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The genome of Mycobacterium tuberculosis (Mtb) harbors the genetic machinery for assembly of the Fimbrial low-molecular-weight protein (Flp) type IV pilus. Presumably, the Flp pilus is essential for pathogenesis. However, it remains unclear whether t
Externí odkaz:
https://doaj.org/article/dc25767b0d8244438cbc0c27ed2c2cb9
Autor:
Erin, Leigh Wood, Akshaya, Tatke, Alex, Viehmann, Melika, Ashtiani, Richard L, Friedman, Michael, Kopcha, Adam C, Fisher
Publikováno v:
International Journal of Pharmaceutics. 625:122119
An international sampling study yielded 69 samples of extended-release prescription pharmaceuticals for legal sale in the U.S. Samples included 29 lots of innovator and 40 lots of generic solid oral extended-release drugs manufactured at 16 different
Autor:
Dong-Min Shin, Bo-Young Jeon, Hye-Mi Lee, Hyo Sun Jin, Jae-Min Yuk, Chang-Hwa Song, Sang-Hee Lee, Zee-Won Lee, Sang-Nae Cho, Jin-Man Kim, Richard L Friedman, Eun-Kyeong Jo
Publikováno v:
PLoS Pathogens, Vol 6, Iss 12, p e1001230 (2010)
The "enhanced intracellular survival" (eis) gene of Mycobacterium tuberculosis (Mtb) is involved in the intracellular survival of M. smegmatis. However, its exact effects on host cell function remain elusive. We herein report that Mtb Eis plays essen
Externí odkaz:
https://doaj.org/article/7a68f703324c4101bda1cdde14254c6b
Autor:
Adrienne M. Wang, Candace Hsieh, Chris J. Langford, Robert O. Dillman, Lisa N. Abaid, James A. Langford, Ramez N. Eskander, Krystal Carta, Gabriel Nistor, Bradley R. Corr, James R. Mason, Richard L. Friedman
Publikováno v:
Cancer Research. 80:CT189-CT189
Standard treatment of primary ovarian epithelial cancer has improved, but 5-year survival is only about 40% for the cohort of patients who present with stage 3 or 4 disease. Adjunctive therapy with patient-specific vaccines may improve outcomes by en
Autor:
Michael Kopcha, Lucinda F. Buhse, Adam C. Fisher, Janet Woodcock, Richard L. Friedman, Melika Ashtiani, Alex Viehmann
Publikováno v:
JAMA Network Open
Key Points Question Are there substantive differences in the major quality attributes of difficult-to-make pharmaceutical products manufactured throughout the world and marketed in the US? Findings In this quality improvement study, all of 252 drug p
Autor:
Richard L. Friedman
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 65:698-712
CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Mic
Autor:
Richard L. Friedman, Andrew Cha, I. Michael Leitman, Burton G. Surick, Dimitrios V. Avgerinos, Omar H. Llaguna
Publikováno v:
The Open Surgery Journal. 3:11-14
Background: Acute appendicitis has historically been considered a clinical diagnosis, necessitating a CT scan only in the face of equivocal signs and symptoms. The purpose of this study is to determine whether or not the liberal use of CT in the work
Autor:
Richard L. Friedman, Clifton E. Barry, Esteban A. Roberts, Chang-Hwa Song, John L. Dahl, Eun-Kyeong Jo, Jun Wei, Linoj P. Samuel
Publikováno v:
Microbiology. 153:529-540
The eis gene of Mycobacterium tuberculosis has been shown to play a role in the survival of the avirulent Mycobacterium smegmatis within the macrophage. In vitro and in vivo analysis of Deltaeis deletion mutants and complemented strains showed no eff
Publikováno v:
FEMS Microbiology Letters. 243:243-249
Reporter systems efficient at monitoring temporal gene expression in slow-growing mycobacteria would significantly aid the characterization of gene expression in specific environments. Bacterial luciferase is a reporter that has not been widely used
Autor:
Wei-Chien Michael Lin, Sergio Perticucci, Scott M. Eisenkop, Richard L. Friedman, Albert L. Pisani, Nick M. Spirtos
Publikováno v:
Gynecologic Oncology. 90:390-396
Objective The purpose of this study was to determine the relative influences of the extent of disease present before surgery and completeness of cytoreduction on survival for patients with advanced ovarian cancer. Methods Patients (408) with stage II