Výsledky vyhledávání - "Richard Klaus"

Akademický článek

Interleukin-10 enhances recruitment of immune cells in the neonatal mouse model of obstructive nephropathy

Autor: Maja Wyczanska, Franziska Thalmeier, Ursula Keller, Richard Klaus, Hamsa Narasimhan, Xingqi Ji, Barbara U. Schraml, Lou M. Wackerbarth, Bärbel Lange-Sperandio

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract Urinary tract obstruction during renal development leads to inflammation, leukocyte infiltration, tubular cell death, and interstitial fibrosis. Interleukin-10 (IL-10) is an anti-inflammatory cytokine, produced mainly by monocytes/macrophage

Externí odkaz: https://doaj.org/article/d0b7fed22c1043aeb2b587eb114bb34e

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Akademický článek

Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)

Background Melanoma is an immune sensitive disease, as demonstrated by the activity of immune check point blockade (ICB), but many patients will either not respond or relapse. More recently, tumor infiltrating lymphocyte (TIL) therapy has shown promi

Externí odkaz: https://doaj.org/article/b199e93aa3494d549053b8485d6551d1

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Akademický článek

Radiation-induced kidney toxicity: molecular and cellular pathogenesis

Autor: Richard Klaus, Maximilian Niyazi, Bärbel Lange-Sperandio

Publikováno v: Radiation Oncology, Vol 16, Iss 1, Pp 1-11 (2021)

Abstract Radiation nephropathy (RN) is a kidney injury induced by ionizing radiation. In a clinical setting, ionizing radiation is used in radiotherapy (RT). The use and the intensity of radiation therapy is limited by normal-tissue damage including

Externí odkaz: https://doaj.org/article/eedf83ad64194297a3082da0721671ac

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Akademický článek

Case Report: Pediatric Renal Sarcoidosis and Prognostic Factors in Reviewed Cases

Autor: Richard Klaus, Annette Friederike Jansson, Matthias Griese, Tomas Seeman, Kerstin Amann, Bärbel Lange-Sperandio

Publikováno v: Frontiers in Pediatrics, Vol 9 (2021)

Background: Pediatric sarcoidosis is a complex inflammatory disorder with multisystemic manifestations. Kidney involvement in children is rare, and prognostic factors are unknown.Case Report and Methods: We report the case of a 16-year-old girl with

Externí odkaz: https://doaj.org/article/ce368b8224f04cadbbc9c77fd979c0b3

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Akademický článek

Chronic Kidney Disease in Boys with Posterior Urethral Valves–Pathogenesis, Prognosis and Management

Autor: Richard Klaus, Bärbel Lange-Sperandio

Publikováno v: Biomedicines, Vol 10, Iss 8, p 1894 (2022)

Posterior urethral valves (PUV) are the most common form of lower urinary tract obstructions (LUTO). The valves can be surgically corrected postnatally; however, the impairment of kidney and bladder development is irreversible and has lifelong implic

Externí odkaz: https://doaj.org/article/64820271ba1c4ae0874372055503d675

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