Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Richard Keijzer"'
Autor:
Matthew D. Martens, Nivedita Seshadri, Lucas Nguyen, Donald Chapman, Elizabeth S. Henson, Bo Xiang, Landon Falk, Arielys Mendoza, Sunil Rattan, Jared T. Field, Philip Kawalec, Spencer B. Gibson, Richard Keijzer, Ayesha Saleem, Grant M. Hatch, Christine A. Doucette, Jason M. Karch, Vernon W. Dolinsky, Ian M. Dixon, Adrian R. West, Christof Rampitsch, Joseph W. Gordon
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-16 (2021)
Abstract Systemic hypoxia is a common element in most perinatal emergencies and is a known driver of Bnip3 expression in the neonatal heart. Bnip3 plays a prominent role in the evolution of necrotic cell death, disrupting ER calcium homeostasis and i
Externí odkaz:
https://doaj.org/article/e1343dcb2c5b484c91d04a2bde3e5a8e
Autor:
Naghmeh Khoshgoo, Robin Visser, Landon Falk, Chelsea A. Day, Dustin Ameis, Barbara M. Iwasiow, Fuqin Zhu, Arzu Öztürk, Sujata Basu, Molly Pind, Agnes Fresnosa, Mike Jackson, Vinaya Kumar Siragam, Gerald Stelmack, Geoffrey G. Hicks, Andrew J. Halayko, Richard Keijzer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a l
Externí odkaz:
https://doaj.org/article/1fa44ab5d33f4684b3412c079afd0d84
Autor:
Michael Cowap, Danielle Stepnuk, Christopher Stockl, Emma Wolfe, Matthew Levesque, Anna C. Shawyer, Rob Balshaw, Suyin A. Lum Min, Richard Keijzer
Publikováno v:
Journal of Pediatric Surgery. 58:828-833
Publikováno v:
Journal of Pediatric Surgery. 58:844-848
Autor:
Stacy Chapman, Muhamad Almiski, Daniel Marko, Debora Sekiguchi, AJ Dawson, Richard Keijzer, Jonathan Fromm, Sara J. Israels
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:209-212
Placental Nanoparticle Uptake-On-a-Chip: The Impact of Trophoblast Syncytialization and Shear Stress
Autor:
Amr Abostait, Jack Tyrrell, Mahmoud Abdelkarim, Shahla Shojaei, Wai Hei Tse, Ibrahim M. El-Sherbiny, Richard Keijzer, Hagar I. Labouta
Publikováno v:
Molecular Pharmaceutics. 19:3757-3769
The placenta is a dynamic and complex organ that plays an essential role in the health and development of the fetus. Placental disorders can affect the health of both the mother and the fetus. There is currently an unmet clinical need to develop nano
Autor:
Shana Kahnamoui, Sujata Basu, Yubin Lei, Daywin Patel, Richard Keijzer, Christopher D. Pascoe
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology.
MicroRNA-200b (miR-200b) has emerged as a therapeutic option for reducing inflammation and airway dysfunction in asthma. miR-200b belongs to a family of miRNAs that regulate epithelial-to-mesenchymal (EMT) transition and IL-33 abundance. In asthma, m
Autor:
Florentine Dylong, Jan Riedel, Gaurang M. Amonkar, Nicole Peukert, Paula Lieckfeldt, Katinka Sturm, Benedikt Höxter, Wai Hei Tse, Yuichiro Miyake, Steffi Mayer, Richard Keijzer, Martin Lacher, Xingbin Ai, Jan-Hendrik Gosemann, Richard Wagner
Background & ObjectiveAbnormal lung development is the main cause of morbidity and mortality in neonates with congenital diaphragmatic hernia (CDH), a common birth defect (1:2500) of largely unknown pathobiology. Recent studies discovered that inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2c07983fc3d43d8d982e13c351cacf
https://doi.org/10.1101/2023.04.07.536002
https://doi.org/10.1101/2023.04.07.536002
Autor:
Moritz Markel, Gabrielle Derraugh, Martin Lacher, Shaikh Iqbal, Robert Balshaw, Suyin A. Lum Min, Richard Keijzer
Publikováno v:
Journal of Pediatric Surgery. 57:829-832
The benefit of elective resection of congenital lung malformations continues to be debated. Proponents of resection endorse a decreased risk of respiratory complications as one indication for surgery. Our study aimed to compare the prevalence of resp
Autor:
Michael Cowap, Gabrielle Derraugh, Anna C. Shawyer, Rob Balshaw, Suyin A. Lum Min, Richard Keijzer
Publikováno v:
Journal of Pediatric Surgery. 57:851-854
The aim of this study was to assess real-world educational outcomes and developmental disorders in patients with a history of Hirschsprung disease compared to an age-matched control group.With ethics approval (H2016:014) a retrospective cohort study