Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Richard Karlsson Linnér"'
Autor:
Peter B. Barr, Travis T. Mallard, Sandra Sanchez-Roige, Holly E. Poore, Richard Karlsson Linnér, COGA Collaborators, Irwin D. Waldman, Abraham A. Palmer, K. Paige Harden, Danielle M. Dick
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Genome-wide association studies (GWAS) identify genetic variants associated with a trait, regardless of how those variants are associated with the outcome. Characterizing whether variants for psychiatric outcomes operate via specific versus
Externí odkaz:
https://doaj.org/article/2de6535822744d08ae87752fc9242f97
Autor:
Philipp D. Koellinger, Aysu Okbay, Hyeokmoon Kweon, Annemarie Schweinert, Richard Karlsson Linnér, Jan Goebel, David Richte, Lisa Reiber, Bettina Maria Zweck, Daniel W. Belsky, Pietro Biroli, Rui Mata, Elliot M. Tucker-Drob, K. Paige Harden, Gert Wagner, Ralph Hertwig
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/a0660ff29f014ed58237826c404668ce
Autor:
Travis T. Mallard, Richard Karlsson Linnér, Andrew D. Grotzinger, Sandra Sanchez-Roige, Jakob Seidlitz, Aysu Okbay, Ronald de Vlaming, S. Fleur W. Meddens, Abraham A. Palmer, Lea K. Davis, Elliot M. Tucker-Drob, Kenneth S. Kendler, Matthew C. Keller, Philipp D. Koellinger, K. Paige Harden
Publikováno v:
Cell Genomics, Vol 2, Iss 6, Pp 100140- (2022)
Summary: Understanding which biological pathways are specific versus general across diagnostic categories and levels of symptom severity is critical to improving nosology and treatment of psychopathology. Here, we combine transdiagnostic and dimensio
Externí odkaz:
https://doaj.org/article/e46aa5b1293c4d778b4c92cbacfead66
Autor:
Camille M. Williams, Holly Poore, Peter T. Tanksley, Hyeokmoon Kweon, Natasia S. Courchesne-Krak, Diego Londono-Correa, Travis T. Mallard, Peter Barr, Philipp D. Koellinger, Irwin D. Waldman, Sandra Sanchez-Roige, K. Paige Harden, Abraham A Palmer, Danielle M. Dick, Richard Karlsson Linnér
Publikováno v:
bioRxiv
Proprietary genetic datasets are valuable for boosting the statistical power of genome-wide association studies (GWASs), but their use can restrict investigators from publicly sharing the resulting summary statistics. Although researchers can resort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9bd36d9adc2e9d7ba5522d6b97ff53
https://doi.org/10.1101/2023.03.21.533641
https://doi.org/10.1101/2023.03.21.533641
Publikováno v:
Journal of Health Economics, 81:102556, 1-15. Elsevier
Karlsson Linnér, R & Koellinger, P D 2022, ' Genetic risk scores in life insurance underwriting ', Journal of Health Economics, vol. 81, 102556, pp. 1-15 . https://doi.org/10.1016/j.jhealeco.2021.102556
Karlsson Linnér, R & Koellinger, P D 2022, ' Genetic risk scores in life insurance underwriting ', Journal of Health Economics, vol. 81, 102556, pp. 1-15 . https://doi.org/10.1016/j.jhealeco.2021.102556
Genetic tests that predict the lifetime risk of common medical conditions are fast becoming more accurate and affordable. The life insurance industry is interested in using predictive genetic tests in the underwriting process, but more research is ne
Autor:
Scott I. Vrieze, Mengzhen Liu, K. Paige Harden, Trey Ideker, Karin J. H. Verweij, Kathleen Mullan Harris, Sandra Sanchez-Roige, Abraham A. Palmer, Ronald de Vlaming, Dajiang J. Liu, Irwin D. Waldman, Philipp Koellinger, Richard Karlsson Linnér, James W. Madole, Peter B. Barr, Joel Gelernter, Andrew D. Grotzinger, Morgan N. Driver, Rachel L. Kember, Emma C. Johnson, Jorim J. Tielbeek, Henry R. Kranzler, Sara Brin Rosenthal, Holly E. Poore, Elliot M. Tucker-Drob, Danielle M. Dick, Travis T. Mallard, Hang Zhou, Joëlle A. Pasman
Publikováno v:
Nature Neuroscience, 376
Nature Neuroscience, 376, 1835
Nature Neuroscience, 24(10), 1367-1376. Nature Publishing Group
Nature neuroscience, 24(10), 1367-1376. Nature Publishing Group
COGA Collaborators 2021, ' Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction ', Nature Neuroscience, vol. 24, no. 10, pp. 1367-1376 . https://doi.org/10.1038/s41593-021-00908-3
Nature Neuroscience, 376, 1835
Nature Neuroscience, 24(10), 1367-1376. Nature Publishing Group
Nature neuroscience, 24(10), 1367-1376. Nature Publishing Group
COGA Collaborators 2021, ' Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction ', Nature Neuroscience, vol. 24, no. 10, pp. 1367-1376 . https://doi.org/10.1038/s41593-021-00908-3
Contains fulltext : 237013.pdf (Publisher’s version ) (Closed access) Behaviors and disorders related to self-regulation, such as substance use, antisocial behavior and attention-deficit/hyperactivity disorder, are collectively referred to as exter
Autor:
Abraham A. Palmer, Travis T. Mallard, Peter B. Barr, Sandra Sanchez-Roige, Holly E. Poore, Richard Karlsson Linnér, Irwin D. Waldman, K. Paige Harden, Danielle M. Dick
Publikováno v:
Translational psychiatry, vol 12, iss 1
ImportanceCharacterizing whether genetic variants for psychiatric outcomes operate via specific versus general pathways provides more informative measures of genetic risk, and, potentially, allows us to design more targeted prevention and interventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384d664c5aa5c975ccbe8ca9790c080f
https://escholarship.org/uc/item/8b78075v
https://escholarship.org/uc/item/8b78075v
Autor:
JooEun Kang, Victor M. Castro, Michael Ripperger, Sanan Venkatesh, David Burstein, Richard Karlsson Linnér, Daniel B. Rocha, Yirui Hu, Drew Wilimitis, Theodore Morley, Lide Han, Rachel Youngjung Kim, Yen-Chen Anne Feng, Tian Ge, Stephan Heckers, Georgios Voloudakis, Christopher Chabris, Panos Roussos, Thomas H McCoy, Colin G. Walsh, Roy H. Perlis, Douglas M. Ruderfer
Treatment resistant depression (TRD), often defined by absence of symptomatic remission following at least two adequate treatment trials, occurs in roughly a third of all individuals with major depressive disorder (MDD). Prior work has suggested a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17f1ab25e91fc48bbc6e1787f937278b
https://doi.org/10.1101/2022.08.10.22278630
https://doi.org/10.1101/2022.08.10.22278630
Autor:
Peter B. Barr, Morgan N. Driver, Sally I-Chun Kuo, Mallory Stephenson, Fazil Aliev, Richard Karlsson Linnér, Jesse Marks, Andrey P. Anokhin, Kathleen Bucholz, Grace Chan, Howard J. Edenberg, Alexis C. Edwards, Meredith W. Francis, Dana B. Hancock, K. Paige Harden, Chella Kamarajan, Jaakko Kaprio, Sivan Kinreich, John R. Kramer, Samuel Kuperman, Antti Latvala, Jacquelyn L. Meyers, Abraham A. Palmer, Martin H. Plawecki, Bernice Porjesz, Richard J. Rose, Marc A. Schuckit, Jessica E. Salvatore, Danielle M. Dick
Publikováno v:
Molecular Psychiatry, 27, 4633-4641. Springer Science and Business Media LLC
Mol Psychiatry
Molecular psychiatry, vol 27, iss 11
Mol Psychiatry
Molecular psychiatry, vol 27, iss 11
Substance use disorders (SUDs) incur serious social and personal costs. Risk for SUDs is complex, ranging from social conditions to individual genetic variation. We examined whether models that include a clinical/environmental risk index (CERI) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f0485dd1c8faec9422d074d659cfbe
https://doi.org/10.1101/2022.01.27.22269750
https://doi.org/10.1101/2022.01.27.22269750
Autor:
Magnus Johannesson, Hariharan Jayashankar, Avshalom Caspi, David Laibson, Matt McGue, Sven Oskarsson, Alexander I. Young, Nancy Wang, Jeremy Freese, David A. Hinds, William G. Iacono, Andrew Steptoe, Lili Milani, Casper A.P. Burik, Aysu Okbay, Grant Goldman, K. Paige Harden, Jonathan P. Beauchamp, Elliot M. Tucker-Drob, Rafael Ahlskog, Peter M. Visscher, Michael Bennett, Aaron Kleinman, Patrick Turley, Travis T. Mallard, Philipp Koellinger, Olesya Ajnakina, David Cesarini, Tõnu Esko, Michelle N. Meyer, Daniel J. Benjamin, Joel Becker, Benjamin Williams, Kathleen Mullan Harris, Terrie E. Moffitt, Richie Poulton, Richard Karlsson Linnér, Pamela Herd, David L. Corcoran, Patrik K. E. Magnusson, Karen Sugden, Daniel W. Belsky
Polygenic indexes (PGIs) are DNA-based predictors. Their value for research in many scientific disciplines is rapidly growing. As a resource for researchers, we used a consistent methodology to construct PGIs for 47 phenotypes in 11 datasets. To maxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f578513b1b3fadbab5e14ff2f9ad1039
https://doi.org/10.1101/2021.05.08.443158
https://doi.org/10.1101/2021.05.08.443158