Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Richard K. Sterling"'
Autor:
Chathur Acharya, Sara McGeorge, Andrew Fagan, James B. Wade, Hannah Lee, Velimir Luketic, Richard K. Sterling, Leroy Thacker, Jasmohan S. Bajaj
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2867-2875 (2022)
Abstract Driving is independently affected by cirrhosis and hepatic encephalopathy (HE) and alcohol/substance use, but their concomitant impact is unclear. We aimed to determine the impact of alcohol and other substances on driving‐simulator perfor
Externí odkaz:
https://doaj.org/article/bfc1e996b157470e980f4d651825cbf0
Autor:
Priyanka Parajuli, Roy Sabo, Rasha Alsaadawi, Amanda Robinson, Evan French, Richard K. Sterling
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Background: The Fibrosis-4 (FIB-4) index, a simple index that includes age, liver enzymes, and platelet count has been studied as a tool to identify patients at a risk of requiring mechanical ventilation due to its high negative predictive
Externí odkaz:
https://doaj.org/article/34271409e8654743947ecf4e9ad9a457
Autor:
Richard K. Sterling, Dongho Shin, Yongyun Shin, Evan French, Michael P. Stevens, Jasmohan S. Bajaj, Marjolein DeWit, Arun J. Sanyal
Publikováno v:
Hepatology Communications, Vol 5, Iss 9, Pp 1605-1615 (2021)
Simple tests of routine data are needed for those with severe acute respiratory syndrome coronavirus 2, which causes corona virus disease 2019 (COVID‐19), to help identify those who may need mechanical ventilation (MV). In this study, we aimed to d
Externí odkaz:
https://doaj.org/article/ff0987bec8d64d8fb88a89f00c07221f
Autor:
Tanner Grudda, Hyon S. Hwang, Maraake Taddese, Jeffrey Quinn, Mark S. Sulkowski, Richard K. Sterling, Ashwin Balagopal, Chloe L. Thio
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
The focus of hepatitis B functional cure, defined as sustained loss of hepatitis B virus (HBV) surface antigen (HBsAg) and HBV DNA from blood, is on eliminating or silencing the intranuclear template for HBV replication, covalently closed circular DN
Externí odkaz:
https://doaj.org/article/4ae31255e99b4eb3a92cbb60ecbdf52f
Autor:
Jasmohan S. Bajaj, Amirhossein Shamsaddini, Andrew Fagan, Richard K. Sterling, Edith Gavis, Alexander Khoruts, Michael Fuchs, Hannah Lee, Masoumeh Sikaroodi, Patrick M. Gillevet
Publikováno v:
Hepatology Communications, Vol 5, Iss 2, Pp 258-271 (2021)
Antibiotic resistance leads to poor outcomes in cirrhosis. Fecal microbiota transplant (FMT) is associated with reduction in antibiotic resistance gene (ARG) burden in patients without cirrhosis; however, the impact in cirrhosis is unclear. We aimed
Externí odkaz:
https://doaj.org/article/dc398ecf9c9847169a2a41fe9ca127f4
Autor:
Marcus Healey, Richard K. Sterling
Publikováno v:
Biology, Vol 11, Iss 12, p 1833 (2022)
Background and aims: In alcoholic hepatitis (AH), increases in the total bilirubin (TB) and the prothrombin time (PT), which are included in the Maddrey’s discriminant function (MDF) and the model for end-stage liver disease (MELD), are associated
Externí odkaz:
https://doaj.org/article/95f2561b72f740eca20dae0bd4375099
Autor:
Daniel Traum, Yue J. Wang, Kathleen B. Schwarz, Jonathan Schug, David K.H. Wong, Harry L.A. Janssen, Norah A. Terrault, Mandana Khalili, Abdus S. Wahed, Karen F. Murray, Phillip Rosenthal, Simon C. Ling, Norberto Rodriguez-Baez, Richard K. Sterling, Daryl T.Y. Lau, Timothy M. Block, Michael D. Feldman, Elizabeth E. Furth, William M. Lee, David E. Kleiner, Anna S. Lok, Klaus H. Kaestner, Kyong-Mi Chang
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Studies of human hepatitis B virus (HBV) immune pathogenesis are hampered by limited access to liver tissues and technologies for detailed analyses. Here, utilizing imaging mass cytometry (IMC) to simultaneously detect 30 immune, viral, and structura
Externí odkaz:
https://doaj.org/article/93b831a5139543daa027542543de4d77
Autor:
Ashwin Balagopal, Tanner Grudda, Ruy M. Ribeiro, Yasmeen S. Saad, Hyon S. Hwang, Jeffrey Quinn, Michael Murphy, Kathleen Ward, Richard K. Sterling, Yang Zhang, Alan S. Perelson, Mark S. Sulkowski, William O. Osburn, Chloe L. Thio
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
There is no cure for the more than 270 million people chronically infected with HBV. Nucleos(t)ide analogs (NUCs), the mainstay of anti-HBV treatment, block HBV reverse transcription. NUCs do not eliminate the intranuclear covalently closed circular
Externí odkaz:
https://doaj.org/article/136740c7fc1d43fba073ba9d5632fde6
Autor:
Leigh P. Johnson, Richard K. Sterling
Publikováno v:
Biology, Vol 9, Iss 4, p 87 (2020)
(1) Background: Direct-acting antiviral therapy for chronic hepatitis C virus (HCV) infection is associated with high sustained virologic response (SVR) and overcomes negative predictive factors, including steatosis, in patients without human immunod
Externí odkaz:
https://doaj.org/article/1a75da6be52f4f7ab73615ee2b9e7559
Autor:
Mitchell L. Shiffman, M.D., Richard K. Sterling, Melissa Contos, Sarah Hubbard, April Long, Velimir A. Luketic, R. Todd Stravitz, Michael Fuchs, Arun J. Sanyal
Publikováno v:
Annals of Hepatology, Vol 13, Iss 4, Pp 340-349 (2014)
Background and aims. The histologic hallmarks of chronic HCV include inflammation and fibrosis. The impact of interferon therapy on liver histology was evaluated.Material and methods. The study population consisted of 348 patients with chronic HCV wh
Externí odkaz:
https://doaj.org/article/cc9b76bcfef7416a8dbde63de9697701