Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Richard K Sterling"'
Autor:
Thananya Jinato, Masoumeh Sikaroodi, Andrew Fagan, Richard K Sterling, Hannah Lee, Puneet Puri, Brian C Davis, Michael Fuchs, Edith Gavis, Patrick M Gillevet, Jasmohan S Bajaj
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTCognitive dysfunction due to minimal hepatic encephalopathy (MHE) adversely impacts patients with cirrhosis and more precise therapies are needed. Gut-brain axis changes are therapeutic targets, but prior studies have largely focused on bacte
Externí odkaz:
https://doaj.org/article/12e2bb4cf2af4065a1c7352a1baa11ed
Autor:
Jasmohan S Bajaj, Amirhossein Shamsaddini, Chathur Acharya, Andrew Fagan, Masoumeh Sikaroodi, Edith Gavis, Sara McGeorge, Alexander Khoruts, Michael Fuchs, Richard K Sterling, Hannah Lee, Patrick M Gillevet
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Background & Aims Altered gut microbiota is associated with poor outcomes in cirrhosis, including infections and hepatic encephalopathy (HE). However, the role of bacterial virulence factors (VFs) is unclear. Aim: Define association of VFs with cirrh
Externí odkaz:
https://doaj.org/article/ff88e34907614f2796426c1ee8a5b73b
Autor:
Donna M Evon, Paul W Stewart, Jipcy Amador, Marina Serper, Anna S Lok, Richard K Sterling, Souvik Sarkar, Carol E Golin, Bryce B Reeve, David R Nelson, Nancy Reau, Joseph K Lim, K Rajender Reddy, Adrian M Di Bisceglie, Michael W Fried
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0196908 (2018)
BACKGROUND:Symptom burden, medical comorbidities, and functional well-being of patients with chronic hepatitis C virus (HCV) initiating direct acting antiviral (DAA) therapy in real-world clinical settings are not known. We characterized these patien
Externí odkaz:
https://doaj.org/article/7e51805751e8433faa26e2146543c158
Autor:
Jasmohan S Bajaj, Douglas M Heuman, Arun J Sanyal, Phillip B Hylemon, Richard K Sterling, R Todd Stravitz, Michael Fuchs, Jason M Ridlon, Kalyani Daita, Pamela Monteith, Nicole A Noble, Melanie B White, Andmorgan Fisher, Masoumeh Sikaroodi, Huzefa Rangwala, Patrick M Gillevet
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60042 (2013)
Hepatic encephalopathy (HE) represents a dysfunctional gut-liver-brain axis in cirrhosis which can negatively impact outcomes. This altered gut-brain relationship has been treated using gut-selective antibiotics such as rifaximin, that improve cognit
Externí odkaz:
https://doaj.org/article/45dc96f92b3e4866b15094e7e2c6d7f9
Autor:
Richard K Sterling, Arun J Sanyal
Publikováno v:
Canadian Journal of Gastroenterology, Vol 14, Iss Suppl D, Pp 122D-128D (2000)
Complications of portal hypertension are the Achilles heel of end-stage liver disease. Although initially developed in the 1960s, transjugular intrahepatic portosystemic shunts (TIPS) have recently gained popularity for decompressing the portal vein
Externí odkaz:
https://doaj.org/article/26a62bb38a6540989255dd5ff7c3d791
Autor:
Andrew Fagan, Edith A. Gavis, Mary Leslie Gallagher, Travis Mousel, Brian Davis, Puneet Puri, Richard K. Sterling, Velimir A. Luketic, Hannah Lee, Scott C. Matherly, Arun J. Sanyal, R. Todd Stravitz, Vaishali Patel, Mohammad S. Siddiqui, Amon Asgharpour, Michael Fuchs, Leroy Thacker, Jasmohan S. Bajaj
Publikováno v:
Journal of Hepatology. 78:312-321
Even after recovery from overt hepatic encephalopathy (HE), minimal HE (MHE), which impairs quality of life (QoL), can persist. A double-blind, placebo-controlled randomized clinical trial was performed to determine the impact of albumin vs. saline o
Autor:
Jasmohan S Bajaj, Marcela Peña-Rodriguez, Alex La Reau, Wendy Phillips, Michael Fuchs, Brian C Davis, Richard K Sterling, Masoumeh Sikaroodi, Andrew Fagan, Amirhossein Shamsaddini, Zachariah Henseler, Tonya Ward, Puneet Puri, Hannah Lee, Patrick M Gillevet
Publikováno v:
Gut. 72:759-771
ObjectiveFirst decompensation development is a critical milestone that needs to be predicted. Transkingdom gut microbial interactions, including archaeal methanogens, may be important targets and predictors but a longitudinal approach is needed.Desig
Autor:
Nikita Chadha, Richard K. Sterling
Publikováno v:
Current Hepatology Reports. 21:68-75
Autor:
Jasmohan S. Bajaj, Marcela Peňa Rodriguez, Andrew Fagan, Sara McGeorge, Richard K. Sterling, Hannah Lee, Velimir Luketic, Michael Fuchs, Brian C. Davis, Masoumeh Sikaroodi, Patrick M. Gillevet
Publikováno v:
Hepatology. 76:1723-1734
Gut microbiota, including bacteria and phages, are altered in cirrhosis, but their role during infections and spontaneous bacterial peritonitis (SBP) prophylaxis is unclear. Our aim was determine metagenomic changes in gut bacteria; phages and their
Autor:
Chloe L Thio, Maraake Taddese, Yasmeen Saad, Kristina Zambo, Ruy M Ribeiro, Tanner Grudda, Mark S Sulkowski, Richard K Sterling, Yang Zhang, Eric D Young, Hyon S Hwang, Ashwin Balagopal
Publikováno v:
The Journal of Infectious Diseases.
Background Nucleos(t)ide analogues (NUCs) rarely cure chronic hepatitis B (CHB) because they do not eliminate covalently closed circular deoxyribonucleic acid, the stable replication template. In hepatitis B e antigen (HBeAg)-positive CHB during NUCs