Výsledky vyhledávání - "Richard K Nelson"

Akademický článek

A dexamethasone prodrug reduces the renal macrophage response and provides enhanced resolution of established murine lupus nephritis.

Autor: Fang Yuan, Dana E Tabor, Richard K Nelson, Hongjiang Yuan, Yijia Zhang, Jenny Nuxoll, Kimberly K Bynoté, Subodh M Lele, Dong Wang, Karen A Gould

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e81483 (2013)

We evaluated the ability of a macromolecular prodrug of dexamethasone (P-Dex) to treat lupus nephritis in (NZB × NZW)F1 mice. We also explored the mechanism underlying the anti-inflammatory effects of this prodrug. P-Dex eliminated albuminuria in mo

Externí odkaz: https://doaj.org/article/5ed0abc4a4504c2fbd2ff04d75d0ac4e

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Akademický článek

A network model of borderline personality traits, aggression, and self-harm

Autor: Richard K. Nelson, Alisson N.S. Lass, Jennifer R. Fanning, Michael S. McCloskey, E. Samuel Winer, Mitchell E. Berman

Publikováno v: Journal of Affective Disorders Reports, Vol 8, Iss , Pp 100330- (2022)

Background: Cluster B personality disorders (PDs), which include borderline, antisocial, histrionic, and narcissistic PD, are characterized by impulsivity, emotionality, and dramatic behavior. Cluster B PDs are therefore associated with increased agg

Externí odkaz: https://doaj.org/article/d02262ca2f2342f2a4a3a9fbb96df676

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An Lck–cre transgene accelerates autoantibody production and lupus development in (NZB × NZW)F1 mice

Autor: Richard K. Nelson, Karen A. Gould

Publikováno v: Lupus. 25:137-154

Lupus is an autoimmune disease characterized by the development of antinuclear autoantibodies and immune complex-mediated tissue damage. T cells in lupus patients appear to undergo apoptosis at an increased rate, and this enhanced T cell apoptosis ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a89efb71329032a41a3594690b42de5
https://doi.org/10.1177/0961203315603139

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Dexamethasone prodrug treatment prevents nephritis in lupus-prone (NZB × NZW)F1 mice without causing systemic side effects

Autor: Karen A. Gould, Yijia Zhang, Dong Wang, Mohammed P. Akhter, Fang Yuan, Richard K. Nelson, Dana E. Tabor

Publikováno v: Arthritis & Rheumatism. 64:4029-4039

Objective To evaluate the potentially improved therapeutic efficacy and safety of nephrotropic macromolecular prodrugs of glucocorticoids (GCs) for the treatment of lupus nephritis. Methods Lupus-prone female (NZB × NZW)F1 mice received monthly inje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4be06b845a27a9c9f5d3a01f4f41af
https://doi.org/10.1002/art.34667

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High Frequency Vibration Analysis Performed by a Statistical Energy Analysis Formulation and an Energy Finite Element Formulation

Autor: Nickolas Vlahopoulos, Luis Octavio Garza-Rios, Richard K. Nelson

Publikováno v: Noise Control and Acoustics.

The Energy Finite Element Analysis (EFEA) offers significant advantages in the areas of model generation, interpretation of results, and definition of design variables for parametric analyses, with respect to the established Statistical Energy Analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8611680743e429acc2dc7b58d025e6e8
https://doi.org/10.1115/imece1998-0530

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