Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Richard K Fisher"'
Autor:
Richard K. Fisher, Phillip C. West, Samuel I. Mattern-Schain, Michael D. Best, Stacy S. Kirkpatrick, Raymond A. Dieter, Joshua D. Arnold, Michael R. Buckley, Michael M. McNally, Michael B. Freeman, Oscar H. Grandas, Deidra J. H. Mountain
Publikováno v:
Nanomaterials, Vol 11, Iss 3, p 825 (2021)
Lipid nanoparticles have become increasingly popular delivery platforms in the field of gene therapy, but bench-to-bedside success has been limited. Many liposomal gene vectors are comprised of synthetic cationic lipids, which are associated with lip
Externí odkaz:
https://doaj.org/article/417343aefefb4e48ab74582144011023
Autor:
Deidra J.H. Mountain, Phillip C. West, Joshua D. Arnold, Michael R. Buckley, Samuel I. Mattern-Schain, Michael M. McNally, Stacy S. Kirkpatrick, Oscar H. Grandas, Raymond A. Dieter, Michael D. Best, Richard K. Fisher, Michael B. Freeman
Publikováno v:
Nanomaterials
Volume 11
Issue 3
Nanomaterials, Vol 11, Iss 825, p 825 (2021)
Volume 11
Issue 3
Nanomaterials, Vol 11, Iss 825, p 825 (2021)
Lipid nanoparticles have become increasingly popular delivery platforms in the field of gene therapy, but bench-to-bedside success has been limited. Many liposomal gene vectors are comprised of synthetic cationic lipids, which are associated with lip
Autor:
Samuel I. Mattern-Schain, Michael D. Best, Taylor M. Harris, Oscar H. Grandas, Richard K. Fisher, Lauren B. Grimsley, Deidra J.H. Mountain, Philip C. West
Publikováno v:
Chemistry and Physics of Lipids. 218:149-157
Liposomal delivery systems (LDSs) have been at the forefront of medicinal nanotechnology for over three decades. Increasing LDS association to target cells and cargo delivery is crucial to bolstering overall nanodrug efficacy. Our laboratory aims to
Autor:
Richard K. Fisher, Samuel I. Mattern-Schain, Lauren B. Grimsley, Deidra J.H. Mountain, Michael D. Best, Oscar H. Grandas, Stacy S. Kirkpatrick
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Introduction: Our laboratory aims to develop biocompatible nanocarriers for molecular therapeutics aimed at vascular pathology. We have previously established a liposome platform that is an effective delivery system for RNAi in vascular smooth muscle
Autor:
Jonathan S Cudnik, Phillip C West, Richard K Fisher, Sam Mattern-Schain, Michael Best, Stacy S Kirkpatrick, Michael B Freeman, Oscar H Grandas, Deidra J Mountain
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Objectives: Vascular intervention results in intimal denudation, exposure of the sub-endothelial matrix, and subsequent intimal hyperplasia (IH), under the control of numerous remodeling mechanisms. Reduction of IH-induced restenosis may be achieved
Autor:
Michael B. Freeman, Richard K. Fisher, Stacy S. Kirkpatrick, Michael D. Best, Oscar H. Grandas, Samuel I. Mattern-Schain, Deidra J.H. Mountain
Publikováno v:
The Journal of surgical research. 219
Background We have previously defined mechanisms of intimal hyperplasia that could be targets for molecular therapeutics aimed at vascular pathology. However, biocompatible nanocarriers are needed for effective delivery. Cationic liposomes (CLPs) hav
Autor:
Michael B. Freeman, Brian M. Freeman, Richard K. Fisher, Deidra J.H. Mountain, Junior Univers, Oscar H. Grandas, Frederick A. Klein, Stacy S. Kirkpatrick
Publikováno v:
The Journal of surgical research. 207
Background Androgen deficiency (AD) is associated with increased risk of vascular disease. Dysfunctional remodeling of the vessel wall and atypical proliferative potential of vascular smooth muscle cells (VSMCs) are fundamental processes in the devel
Autor:
Michael M. McNally, Scott L. Stevens, Lauren B. Grimsley, M. Ryan Buckley, Richard K. Fisher, Oscar H. Grandas, Raymond A. Dieter, Deidra J.H. Mountain, Michael B. Freeman, Joshua D. Arnold
Publikováno v:
Journal of Vascular Surgery. 69:e15
Publikováno v:
International Journal of Fluid Machinery and Systems. 2:315-323
Pressure oscillations triggered by the unstable interaction of dynamic flow features of the hydraulic turbine with the hydraulic plant system - including the electrical design - can at times reach significant levels and could lead to damage of plant
Autor:
Deidra J.H. Mountain, Wei Zhang, Chao Pu, Richard K. Fisher, Lu Huang, Wei He, Yanfei Gao, Peter K. Liaw
Publikováno v:
Acta biomaterialia. 25
Despite the prevalent use of crystalline alloys in current vascular stent technology, new biomaterials are being actively sought after to improve stent performance. In this study, we demonstrated the potential of a Zr–Al–Fe–Cu bulk metallic gla