Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Richard Joseph Pye"'
Autor:
Carole Eliane Andree Maillol, Richard Storer, Severine Danielle Poignant, Peter David Johnson, Renate van Well, Stephen Paul Wren, Jonathon M. Tinsley, Adam G. Lambert, Gary Nugent, Francis Xavier Wilson, Fraser J. Wilkes, Colin Richard Dorgan, Richard Vickers, Graham Michael Wynne, Cristina Lecci, Richard Joseph Pye, Olivier De Moor, Paul Damien Price
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4828-4831
Families of 2-arylbenzotriazoles and 2-arylindazoles that show positive effects in screens predictive of endogenous utrophin upregulation have been identified. Synthesis and structure-activity relationships are described leading to compounds with att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88eb43eff53eb7246db535b17fe5fdd3
https://doi.org/10.1016/j.bmcl.2011.06.047
https://doi.org/10.1016/j.bmcl.2011.06.047
Autor:
Severine Danielle Poignant, Fraser J. Wilkes, Kay E. Davies, Adam G. Lambert, J Vile, P J Middleton, Francis Xavier Wilson, Peter David Johnson, Stephen Paul Wren, Carole Eliane Andree Maillol, Richard Storer, Chancellor, D Lawrence, Collin Richard Dorgan, Richard Vickers, Graham Michael Wynne, A Potter, Cristina Lecci, Paul Damien Price, Gary Nugent, O De Moor, Richard Joseph Pye, R van Well, Jonathon M. Tinsley
Publikováno v:
Journal of Medicinal Chemistry. 54:3241-3250
A series of novel 2-arylbenzoxazoles that upregulate the production of utrophin in murine H2K cells, as assessed using a luciferase reporter linked assay, have been identified. This compound class appears to hold considerable promise as a potential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7d5e973d1a9516da52e0847a018b37
https://doi.org/10.1021/jm200135z
https://doi.org/10.1021/jm200135z
Publikováno v:
Organic letters. 6(15)
[reaction: see text] The tethered aminohydroxylation (TA) of acyclic allylic carbamates has been achieved in a stereospecific and stereoselective manner. Unusually high levels of stereocontrol were observed in the oxidation of 1,1-disubstituted subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d65bea9b4796158e71f4c6c5aa3afd9
http://ora.ox.ac.uk/objects/uuid:daff731d-0536-4f4c-846e-2a71e35fe876
http://ora.ox.ac.uk/objects/uuid:daff731d-0536-4f4c-846e-2a71e35fe876
Publikováno v:
Organic and biomolecular chemistry. 1(12)
Since Sharpless' discovery of the asymmetric aminohydroxylation (AA) reaction, a major challenge for chemists has been to find ways of controlling the regio- and stereochemical outcome of this important reaction. Detailed herein is a review of our no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622097990700980ac3d95fe8d282e1a2
http://ora.ox.ac.uk/objects/uuid:92574b1e-8c4f-428d-9696-5c5169210766
http://ora.ox.ac.uk/objects/uuid:92574b1e-8c4f-428d-9696-5c5169210766
Publikováno v:
Organic & Biomolecular Chemistry. 1:2025
Since Sharpless' discovery of the asymmetric aminohydroxylation (AA) reaction, a major challenge for chemists has been to find ways of controlling the regio- and stereochemical outcome of this important reaction. Detailed herein is a review of our no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ae747a681a00dc16bbaf7b9ad2209f
https://doi.org/10.1039/b305189g
https://doi.org/10.1039/b305189g