Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Richard John Wheeler"'
Autor:
Molly Hair, Ryuji Yanase, Flávia Moreira-Leite, Richard John Wheeler, Jovana Sádlová, Petr Volf, Sue Vaughan, Jack Daniel Sunter
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012054 (2024)
The unicellular parasite Leishmania has a precisely defined cell architecture that is inherited by each subsequent generation, requiring a highly coordinated pattern of duplication and segregation of organelles and cytoskeletal structures. A framewor
Externí odkaz:
https://doaj.org/article/3e00136112804f9f8ba84f15b5898d21
Autor:
Jan Pyrih, Michael Hammond, Aline Alves, Samuel Dean, Jack Daniel Sunter, Richard John Wheeler, Keith Gull, Julius Lukeš
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113083- (2023)
Summary: We have generated a high-confidence mitochondrial proteome (MitoTag) of the Trypanosoma brucei procyclic stage containing 1,239 proteins. For 337 of these, a mitochondrial localization had not been described before. We use the TrypTag datase
Externí odkaz:
https://doaj.org/article/2e86302848f347efa7ac73caef661af2
Autor:
Richard John Wheeler
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein structure. They are able to make very high-quality predictions given a high-quality alignment of the protein sequence with related proteins. These predictions are no
Externí odkaz:
https://doaj.org/article/f5af0dacc2144a69be1c1bdc391e80c7
Autor:
Tom Beneke, François Demay, Edward Hookway, Nicole Ashman, Heather Jeffery, James Smith, Jessica Valli, Tomas Becvar, Jitka Myskova, Tereza Lestinova, Shahaan Shafiq, Jovana Sadlova, Petr Volf, Richard John Wheeler, Eva Gluenz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007828 (2019)
The protozoan parasite Leishmania possesses a single flagellum, which is remodelled during the parasite's life cycle from a long motile flagellum in promastigote forms in the sand fly to a short immotile flagellum in amastigotes residing in mammalian
Externí odkaz:
https://doaj.org/article/9ca55d87fc984bd0871bdf13faa8f1ce
Transition fibres are appendages that surround the distal end of mature basal bodies (also called distal appendages) and are essential for ciliogenesis, but only a small number of proteins have been identified and functionally characterised. Here, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a84e7fcf676a5ee17f88685f7eda2807
https://doi.org/10.1101/2023.05.29.542710
https://doi.org/10.1101/2023.05.29.542710
Genome-wide subcellular protein localisation inTrypanosoma brucei, through our TrypTag project, has comprehensively dissected the molecular organisation of this important pathogen. Powerful as this resource is,T. bruceihas multiple developmental form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d2672e6d276b1c033cea38d55899a8
https://doi.org/10.1101/2022.11.07.515401
https://doi.org/10.1101/2022.11.07.515401
Publikováno v:
Journal of Cell Science. 135
The compartmentalised eukaryotic cell demands accurate targeting of proteins to the organelles in which they function, whether membrane-bound (like the nucleus) or non-membrane-bound (like the nucleolus). Nucleolar targeting relies on positively char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590cf16a6c1db5ae0256081749c37b54
https://doi.org/10.1242/jcs.259701
https://doi.org/10.1242/jcs.259701
Autor:
Richard John Wheeler
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005353 (2017)
Swimming cells typically move along a helical path or undergo longitudinal rotation as they swim, arising from chiral asymmetry in hydrodynamic drag or propulsion bending the swimming path into a helix. Helical paths are beneficial for some forms of
Externí odkaz:
https://doaj.org/article/54d17902ebd143bb8ff349d561a328ee
Autor:
Karen Billington, Clare Halliday, Ross Madden, Philip Dyer, Mark Carrington, Sue Vaughan, Christiane Hertz-Fowler, Samuel Dean, Jack Daniel Sunter, Richard John Wheeler, Keith Gull
Trypanosoma brucei is a prototypical trypanosomatid, an important group of human, animal and plant unicellular parasites. Understanding their complex cell architecture and life cycle is hindered since, as with most eukaryotic microbes, ∼50% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f98ac01d80032893b99039735197a1
https://doi.org/10.1101/2022.06.09.495287
https://doi.org/10.1101/2022.06.09.495287
Autor:
Wheeler, Richard John1 (AUTHOR) richard.wheeler@ndm.ox.ac.uk
Publikováno v:
PLoS ONE. 11/11/2021, Vol. 16 Issue 11, p1-12. 12p.