Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Richard J.O. Barnard"'
Autor:
Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) wer
Externí odkaz:
https://doaj.org/article/3c551d2d1a814a3d84819bbd3a685652
Autor:
Francesco Andrea Procopio, Rémi Fromentin, Deanna A. Kulpa, Jessica H. Brehm, Anne-Gaelle Bebin, Matthew C. Strain, Douglas D. Richman, Una O'Doherty, Sarah Palmer, Frederick M. Hecht, Rebecca Hoh, Richard J.O. Barnard, Michael D. Miller, Daria J. Hazuda, Steven G. Deeks, Rafick-Pierre Sékaly, Nicolas Chomont
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 874-883 (2015)
Background: Quantifying latently infected cells is critical to evaluate the efficacy of therapeutic strategies aimed at reducing the size of the long-lived viral reservoir, but the low frequency of these cells makes this very challenging. Methods: We
Externí odkaz:
https://doaj.org/article/2e7bfa284a9f4d7b88f06a8f37a05e38
Autor:
Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini
Publikováno v:
The Journal of clinical investigation. 132(8)
Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) wer
Publikováno v:
FEBS Letters. 436:1-5
N-Ethylmaleimide-sensitive factor (NSF) plays a key role in vesicular traffic by disassembling and priming SNARE proteins for their function in docking and fusion. We demonstrate that the ATPase activity of NSF is activated by alpha-soluble NSF attac
Publikováno v:
The Journal of Cell Biology
N-ethylmaleimide-sensitive fusion protein (NSF) and alpha-SNAP play key roles in vesicular traffic through the secretory pathway. In this study, NH2- and COOH-terminal truncation mutants of alpha-SNAP were assayed for ability to bind NSF and stimulat
Autor:
Richard J.O. Barnard, Alan Morgan, Allan W. Sudlow, Helena Bodill, Brian W. McFerran, Robert D. Burgoyne
Publikováno v:
FEBS Letters. 393:185-188
Soluble N -ethylmaleimide-sensitive fusion protein attachment proteins (SNAP) proteins function in Ca 2+ -regulated exocytosis. Recent work (Schiavo et al. (1996) Nature 378, 733–736) based on in vitro protein interactions has raised the possibilit
Publikováno v:
Journal of Cell Science. 109:2417-2422
We have examined the effect of alpha-SNAP on exocytosis in adrenal chromaffin cells by direct assay of exocytosis using patch-clamp capacitance analysis. Cells were recorded using the whole cell patch-clamp configuration and the cells dialysed with c
Publikováno v:
Molecular Biology of the Cell. 7:693-701
The binding of alpha-SNAP to the membrane proteins syntaxin, SNAP-25, and synaptobrevin leads to the recruitment of the N-ethylmaleimide-sensitive fusion protein (NSF). ATP hydrolysis by NSF has been suggested to drive conformational changes in one o
Autor:
Richard J.O. Barnard, Robert D. Burgoyne, Alan Morgan, Luke H. Chamberlain, A. V. Kibble, Daphne E. Glenn
Publikováno v:
Biochemical Society transactions. 24(3)