Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Richard J. Upton"'
Autor:
Janelle Gyorffy, Samuel M. Philbrick, Adrian R. Bersabe, Richard J. Upton, Derek A. Mathis, Austin Peters, Alexander Brown
Publikováno v:
Case Reports in Oncological Medicine, Vol 2017 (2017)
Breast cancer rarely metastasizes to the muscles, and it is even more unusual for this phenomenon to result in airway compromise. We present a unique case of an 84-year-old female who presented with neck swelling and upper airway obstruction due to m
Externí odkaz:
https://doaj.org/article/3734a8bad8ce46369b104d228b616172
Autor:
Simon J F, Macdonald, Geoffrey D E, Clarke, Michael D, Dowle, Lee A, Harrison, Simon T, Hodgson, Graham G A, Inglis, Martin R, Johnson, Prit, Shah, Richard J, Upton, Steven B, Walls
Publikováno v:
The Journal of organic chemistry. 64(14)
A flexible, practical, and stereoselective synthesis of enantiomerically pure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd9b13ef74f72d85e684fd8ce230d565
https://pubmed.ncbi.nlm.nih.gov/34237863
https://pubmed.ncbi.nlm.nih.gov/34237863
Publikováno v:
Military Medicine. 185:e919-e922
Cunninghamella species are aggressive, opportunistic fungi that are becoming more commonly reported in immunocompromised patients. We present a case of disseminated Cunninghamella sp. infection after stem cell transplant for refractory multiple myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef47f1b77cd64dfcf7fb25ddf456b7a4
https://doi.org/10.1093/milmed/usz363
https://doi.org/10.1093/milmed/usz363
Autor:
Richard J. Upton, Max W. Robinson, John C. Hollerton, Bob Boughtflower, Sean M. Lynn, Steve C. Besley, Simon A. Readshaw, Alan P. Hill
Publikováno v:
Analytical Chemistry. 89:1772-1777
Universal quantitative detection without the need for analyte reference standards would offer substantial benefits in many areas of analytical science. The quantitative capability of high-performance liquid chromatography (HPLC) with charged aerosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4b3c63c67b2f4285f143f552e13d2f
https://doi.org/10.1021/acs.analchem.6b04060
https://doi.org/10.1021/acs.analchem.6b04060
Autor:
Clement Douault, Tony Kouzarides, Robert J. Sheppard, Hawa Diallo, Paola Grandi, Samuel Robson, Chun-wa Chung, Ka Hing Che, Rab K. Prinjha, Richard J. Upton, Darren Jason Mitchell, Rebecca C. Furze, Emmanuel Hubert Demont, Andrew J. Bannister, Anne-Marie Michon, Robert J. Watson, Christina Rau, Paul Bamborough
Publikováno v:
Angew Chem Int Ed Engl
ATAD2 is a cancer-associated protein whose bromodomain has been described as among the least druggable of that target class. Starting from a potent lead, permeability and selectivity were improved through a dual approach: 1) using CF(2) as a sulfone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4422b24c26e10a43ba070267a1d8114d
https://doi.org/10.1002/anie.201603928
https://doi.org/10.1002/anie.201603928
Autor:
Leanna E. Shuster, Graham G. A. Inglis, Abraham Nudelman, Yanqiu Qian, Grazyna Graczyk-Millbrandt, David Perez, Helen F. Sneddon, Richard J. Upton, Hugo E. Gottlieb
Publikováno v:
Green Chemistry. 18:3867-3878
Residual solvents often appear as nuisance signals in experimental NMR spectra, and many chemists turn to well-known literature sources to quickly identify such peaks. While these publications are very useful, they do not currently include many solve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99844d5a19ff923eb629ded8c28d5ff3
https://doi.org/10.1039/c6gc00446f
https://doi.org/10.1039/c6gc00446f
Autor:
Adrian Reyes Bersabe, Alexander W. Brown, Austin Peters, Samuel M Philbrick, Derek A Mathis, Richard J Upton, Janelle Gyorffy
Publikováno v:
Case Reports in Oncological Medicine, Vol 2017 (2017)
Case Reports in Oncological Medicine
Case Reports in Oncological Medicine
Breast cancer rarely metastasizes to the muscles, and it is even more unusual for this phenomenon to result in airway compromise. We present a unique case of an 84-year-old female who presented with neck swelling and upper airway obstruction due to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cf0ee41174792cdf0a852c0ce9bcea
https://doaj.org/article/3734a8bad8ce46369b104d228b616172
https://doaj.org/article/3734a8bad8ce46369b104d228b616172
Autor:
Philip J. Sidebottom, Sean M. Lynn, Stefano Provera, Richard J. Upton, John C. Hollerton, Roger D. Farrant
Publikováno v:
Magnetic Resonance in Chemistry. 48:753-762
We have developed QUANTAS (QUANTification by Artificial Signal), which is a software-based protocol for concentration measurement by NMR. QUANTAS is an absolute intensity external standard method for quantification by NMR that compensates for various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490960533cf3cf0ff1be340391bc157c
https://doi.org/10.1002/mrc.2647
https://doi.org/10.1002/mrc.2647
Autor:
Melanie Washington, Davina Humphreys, Lesley Nisbet, Philip Alan Skone, Royston C. B. Copley, Simon J. F. Macdonald, Graham G. A. Inglis, Richard J. Upton, Mike D. Barker, Margaret Clackers, Victoria Vinader, Haydn Terence Jones, Michael John Johnston, Iain M. McLay, Derek A. Demaine, Stephen E. Shanahan, David House, Richard Loiseau, Dan Tape, Michael V. Haase, Francois Pacquet, Iain Uings
Publikováno v:
Journal of Medicinal Chemistry. 49:4216-4231
The tetrahydronaphthalene-benzoxazine glucocorticoid receptor (GR) partial agonist 4b was optimized to produce potent full agonists of GR. Aromatic ring substitution of the tetrahydronaphthalene leads to weak GR antagonists. Discovery of an "agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f39bc2e216c3f76a792ae67a2aa0cf0
https://doi.org/10.1021/jm060302x
https://doi.org/10.1021/jm060302x
Autor:
Peter W. Seale, Richard J. Upton, David J. Williams, Stefan Stefaniak, and Andrew J. P. White, Panayiotis Alexandrou Procopiou, Anthony G. M. Barrett, Alan Joseph Hennessy, Ronan Le Vezouet
Publikováno v:
The Journal of Organic Chemistry. 69:1028-1037
The synthesis of a range of highly functionalized peptidomimetic macrocycles has been accomplished using ring-closing metathesis and enyne tandem cross-metathesis-ring-closing metathesis reactions. This approach gives access to rigidified macrocycles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806e69f0f131596c0844f8dd57751de7
https://doi.org/10.1021/jo0352629
https://doi.org/10.1021/jo0352629