Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Richard J. Singer"'
Publikováno v:
RSC Medicinal Chemistry
The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccf781e768c334ef86dc5053c84e0da
https://doi.org/10.1039/d0md00428f
https://doi.org/10.1039/d0md00428f
Autor:
Ayomi S. Perera, Patrick M. Melia, Reece M.D. Bristow, James D. McGettrick, Richard J. Singer, Joseph C. Bear, Rosa Busquets
Publikováno v:
Microporous and Mesoporous Materials. 345:112276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cd9bd2786f8e4ff75f6cc56c04b095
https://doi.org/10.1016/j.micromeso.2022.112276
https://doi.org/10.1016/j.micromeso.2022.112276
Autor:
Fawaz Aldabbagh, Richard J. Singer, Patrick Kielty, Pau Farràs, Patrick McArdle, Jeremy K. Cockcroft, Joseph C. Bear, Darren Conboy, Dennis A. Smith
Publikováno v:
Organicbiomolecular chemistry. 19(12)
Ring-fused benzimidazolequinones are well-known anti-tumour agents, but dimeric ring-fused adducts are new. The alicyclic [1,2-a] ring-fused dimethoxybenzimidazole-benzimidazolequinone (DMBBQ) intermediate allows late-stage functionalization of bis-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb995c8fa6ada8f7bf49f6a39b905fb
https://pubmed.ncbi.nlm.nih.gov/33667287
https://pubmed.ncbi.nlm.nih.gov/33667287
Autor:
Dennis A. Smith, Michael Kennedy, Michael P. Carty, Fawaz Aldabbagh, Patrick McArdle, Patrick Kielty, Peter Cannon, Richard J. Singer
Isosorbide was functionalized with furoxan for the first time to give adducts that release nitric oxide up to 7.5 times faster than the commercial vasodilator, isosorbide-5-mononitrate (Is5N). The synthesis was facilitated by MeMgCl-mediated selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc3d7c00551ce072865428162e55fa8
https://eprints.kingston.ac.uk/id/eprint/41155/3/Singer-R-41155-AAM.pdf
https://eprints.kingston.ac.uk/id/eprint/41155/3/Singer-R-41155-AAM.pdf
Publikováno v:
RSC Adv.. 3:358-361
For the first time, a hydroxy double salt containing an active pharmaceutical agent has been formulated into tablets. The tablets have excellent pharmaceutical properties and release the drug slowly over around 4 h when in conditions representative o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4d32ec9e081899d1d25c6225c40e2a
https://doi.org/10.1039/c2ra21339g
https://doi.org/10.1039/c2ra21339g
The pseudorotating clusters, Li5 and K7, have been identified in an adamantane matrix by EPR spectroscopy. These new clusters were synthesised by depositing the parent alkali metal atoms at 77 K in the hydrocarbon matrix followed by careful annealing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0084fe1e33e2570a13ae1c0ab0323c54
https://doi.org/10.1016/0009-2614(93)85616-v
https://doi.org/10.1016/0009-2614(93)85616-v
Publikováno v:
The Journal of Chemical Physics. 99:6600-6606
Product translational energy release spectra resulting from 248 and 193 nm photodissociation of methyl mercaptan are obtained for the hydrogen atom channels (CH3SH+hν→CH3S+H) by using the high‐n Rydberg time‐of‐flight technique. The spectra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd697953206d374f02fa0755791243fe
https://doi.org/10.1063/1.465852
https://doi.org/10.1063/1.465852
Publikováno v:
Journal of the American Chemical Society. 114:474-477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0229eec3714865357a3564dba7431352
https://doi.org/10.1021/ja00028a012
https://doi.org/10.1021/ja00028a012
Publikováno v:
The Journal of Physical Chemistry. 95:8078-8081
The authors report the center-of-mass translational energy distribution for 193.3-nm photolysis of expansion-cooled C{sub 2}H{sub 2}, using high-n Rydberg-level excitation of nascent H atoms to facilitate high-resolution time-of-flight measurements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503cecc2ee7fb89fe7b1eaa65822cca1
https://doi.org/10.1021/j100174a015
https://doi.org/10.1021/j100174a015
Autor:
Dominic S. Wright, Dietmar Stalke, William Clegg, David R. Armstrong, Donald Barr, Simon R. Drake, Richard J. Singer, Ronald Snaith
Publikováno v:
Angewandte Chemie. 103:1702-1704
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13039d3da59739e63963bf3ffe17f0db
https://doi.org/10.1002/ange.19911031232
https://doi.org/10.1002/ange.19911031232