Výsledky vyhledávání - "Richard J. McMurtrey"

Akademický článek

Multi-compartmental biomaterial scaffolds for patterning neural tissue organoids in models of neurodevelopment and tissue regeneration

Autor: Richard J McMurtrey

Publikováno v: Journal of Tissue Engineering, Vol 7 (2016)

Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional culture of stem cells, and, more recently, also enable high-resolution patterning and organization

Externí odkaz: https://doaj.org/article/dd87bb759bd5404e9ed5666070c0af9d

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Elements of organoid design

Autor: Richard J. McMurtrey

Neural tissue organoids are a powerful tool for investigating numerous disease mechanisms, and for potentially creating novel therapies for several neurological diseases. This work describes several considerations for the design of neural organoids,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd83084830ff440c97c7cafc3802bdda
https://doi.org/10.1016/b978-0-12-812636-3.00002-x

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List of contributors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::724555abcfe4d118817238115bd82e00
https://doi.org/10.1016/b978-0-12-812636-3.00022-5

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Roles of Diffusion Dynamics in Stem Cell Signaling and Three-Dimensional Tissue Development

Autor: Richard J. McMurtrey

Publikováno v: Stem Cells and Development

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have ignited inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c503e48b73888c209ad4d68c7a7538
https://pubmed.ncbi.nlm.nih.gov/28707964

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Analytic and Numerical Models of Oxygen and Nutrient Diffusion, Metabolism Dynamics, and Architecture Optimization in Three-Dimensional Tissue Constructs with Applications and Insights in Cerebral Organoids

Autor: Richard J. McMurtrey

Publikováno v: Tissue Engineering. Part C, Methods

Diffusion models are important in tissue engineering as they enable an understanding of gas, nutrient, and signaling molecule delivery to cells in cell cultures and tissue constructs. As three-dimensional (3D) tissue constructs become larger, more in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdabfa05fa8ae5e2f942db5b6a61716

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Patterned and functionalized nanofiber scaffolds in three-dimensional hydrogel constructs enhance neurite outgrowth and directional control

Autor: Richard J. McMurtrey

Publikováno v: Journal of neural engineering. 11(6)

Neural tissue engineering holds incredible potential to restore functional capabilities to damaged neural tissue. It was hypothesized that patterned and functionalized nanofiber scaffolds could control neurite direction and enhance neurite outgrowth.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb9b3c13f887301fdc74ef7a8f5968b
https://pubmed.ncbi.nlm.nih.gov/25358624

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ISOFLURANE PRECONDITIONING AND POSTCONDITIONING IN RAT HIPPOCAMPAL NEURONS

Autor: Zhiyi Zuo, Richard J. McMurtrey

The volatile anesthetic isoflurane is capable of inducing preconditioning and postconditioning effects in the brain. However, the mechanisms for these neuroprotective effects are not fully understood. Here, we showed that rat hippocampal neuronal cul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9affd99452fef32b2358cb1ab36f7788
https://europepmc.org/articles/PMC2949531/

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