Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Richard J. Levy"'
Publikováno v:
Physiological Reports, Vol 10, Iss 15, Pp n/a-n/a (2022)
Abstract Infants and children are vulnerable to developing propofol infusion syndrome (PRIS) and young age is a risk factor. Cardiac involvement is often prominent and associated with death. However, the mechanisms of pediatric PRIS are poorly unders
Externí odkaz:
https://doaj.org/article/46bde05e66ae453fa4274751c28687f0
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101058- (2020)
The Langendorff-perfused model is a powerful tool to study biological responses in the isolated heart in the absence of confounders. The model has been adapted recently to enable study of the isolated mouse heart and the effects of genetic manipulati
Externí odkaz:
https://doaj.org/article/b879f889590941b7b467b72e131dc611
Autor:
Li Wang, Aili Wang, William W. Supplee, Kayla Koffler, Ying Cheng, Zenaide M.N. Quezado, Richard J. Levy
Publikováno v:
Data in Brief, Vol 13, Iss , Pp 550-556 (2017)
The data presented here detail the changes in size, cellular content, and neuronal density of the developing brain over time with respect to sex in C57Bl/6 mice following neonatal exposure to isoflurane, carbon monoxide, or their combination. Specifi
Externí odkaz:
https://doaj.org/article/4d64bdb44e324c24a228cb0f9787531d
Publikováno v:
Journal of Neurosurgical Anesthesiology. 35:97-103
Publikováno v:
Mitochondrion. 65:1-10
Brown adipose tissue (BAT) mitochondria generate heat via uncoupled respiration due to excessive proton leak through uncoupling proteins (UCPs). We previously found hyperthermia in a newborn mouse model of fragile X syndrome and excessive leak in Fmr
Autor:
Richard J. Levy
Publikováno v:
Carbon Monoxide in Drug Discovery. :286-301
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Autor:
Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc C. Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Joachim Weber, Richard J. Levy, Evgeny V. Pavlov, Elizabeth A. Jonas
Publikováno v:
Cell Death & Differentiation. 29:1874-1887
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Publikováno v:
Pediatric Research. 92:1341-1349
Background Propofol infusion syndrome (PRIS) is a potentially lethal consequence of long-term propofol administration. Children are vulnerable and cardiac involvement is often prominent and associated with mortality. We aimed to determine the mechani
Autor:
Jerri C. Price, Jennifer J. Lee, Caleb Ing, Guohua Li, Jacquelin Narula, Mary K. Clark, Steven Stylianos, Robert A. Whittington, Richard J. Levy, Lena S. Sun
Publikováno v:
Journal of Neurosurgical Anesthesiology. 34:132-135
Publikováno v:
Journal of Visualized Experiments.
The mitochondrial permeability transition pore (mPTP) is a voltage-gated, nonselective, inner mitochondrial membrane (IMM) mega-channel important in health and disease. The mPTP mediates leakage of protons across the IMM during low-conductance openin