Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Richard J. Koletsky"'
Autor:
Pamela St. Jean, Agnes J. Thomas, Richard J. Koletsky, Nicholas J. Schork, Evelyn H. Schlenker, Kingman P. Strohl
Publikováno v:
Journal of Applied Physiology. 82:317-323
Strohl, Kingman P., Agnes J. Thomas, Pamela St. Jean, Evelyn H. Schlenker, Richard J. Koletsky, and Nicholas J. Schork.Ventilation and metabolism among rat strains. J. Appl. Physiol. 82(1): 317–323, 1997.—We examined ventilation and metabolism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3279b699681d0a7c3275d9a801e1b994
https://doi.org/10.1152/jappl.1997.82.1.317
https://doi.org/10.1152/jappl.1997.82.1.317
Autor:
Richard J. Koletsky, Paul Ernsberger
Publikováno v:
Current Opinion in Pharmacology. 7:140-145
Accumulating basic and clinical data support the hypothesis that angiotensin receptor blockers have beneficial effects on glucose and lipid metabolism that are not shared by other classes of antihypertensive agents. These metabolic actions might only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc796eb41d88b2fc5d8170dc4a7457e1
https://doi.org/10.1016/j.coph.2006.11.008
https://doi.org/10.1016/j.coph.2006.11.008
Autor:
Paul Ernsberger, Richard J. Koletsky
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 373:245-258
Reports of beneficial, neutral and adverse impacts of antihypertensive drug classes on glucose and lipid metabolism can be found in human data. Furthermore, mechanisms for these diverse effects are often speculative and controversial. Clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a41999968cd6e54044a0343e53cfd9
https://doi.org/10.1007/s00210-006-0080-3
https://doi.org/10.1007/s00210-006-0080-3
Publikováno v:
Annals of the New York Academy of Sciences. 1009:251-261
Hypertension is commonly accompanied by obesity, hyperlipidemia, and insulin resistance in humans, a cluster of abnormalities known as metabolic syndrome X. With the notable exception of inhibitors of the renin-angiotensin system, which have mildly b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87030dcb4ea7417c0f05017f8cf328a
https://doi.org/10.1196/annals.1304.031
https://doi.org/10.1196/annals.1304.031
Autor:
Sha Liu, Tatsuya Ishizuka, Jacob E. Friedman, Paul Ernsberger, Richard J. Koletsky, David Bedol
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 105:82-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620a17087a455a4f5b2039441ae0dfc4
https://doi.org/10.1055/s-0029-1211908
https://doi.org/10.1055/s-0029-1211908
Publikováno v:
Peptides. 20:1449-1453
Leptin is produced in adipose tissue in the periphery, but its satiety effect is exerted in the CNS that it reaches by a saturable transport system across the blood-brain barrier (BBB). The short form of the leptin receptor has been hypothesized to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dfa09944e4f3197872c264e1888e8c
https://doi.org/10.1016/s0196-9781(99)00156-4
https://doi.org/10.1016/s0196-9781(99)00156-4
Publikováno v:
Annals of the New York Academy of Sciences. 892:315-318
The obese SHR (SHROB strain, Koletsky rat) is a spontaneous genetic knockout for the leptin receptor gene and shows many of the abnormalities that cluster in the human Syndrome X. The SHROB expresses genetic obesity, spontaneous hypertension, hyperin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0259cebfc058206db9de4ed8b6b6f5
https://doi.org/10.1111/j.1749-6632.1999.tb07806.x
https://doi.org/10.1111/j.1749-6632.1999.tb07806.x
Autor:
Paul Ernsberger, Richard J. Koletsky
Publikováno v:
Journal of Social Issues. 55:221-260
The direct medical hazards of obesity, although real, have been overstated. Because current remedies for obesity have little long-term effectiveness, no controlled clinical trial has demonstrated improved longevity after weight loss. In contrast, adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6265cd58f5a7df4cf0c4e0caa284b9b
https://doi.org/10.1111/0022-4537.00114
https://doi.org/10.1111/0022-4537.00114
Publikováno v:
Journal of Hypertension. 16:2001-2005
Objectives We sought to determine whether the sympathetic nervous system plays a role in the hypertensive response to refeeding from a very low-calorie diet (VLCD). Design Cycles of weight loss and regain were induced in the obese spontaneously hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757c7db80ad02dd8311c784f2e4e37e7
https://doi.org/10.1097/00004872-199816121-00022
https://doi.org/10.1097/00004872-199816121-00022
Autor:
Paul Ernsberger, Timothy M. Lehman, David Bedol, Sha Liu, Richard J. Koletsky, Jacob E. Friedman, Tatsuya Ishizuka
Publikováno v:
ResearcherID
The genetically obese Koletsky rat (SHROB, fa k ) has a novel point mutation of the leptin receptor at amino acid +763, resulting in a premature stop codon in the leptin receptor extracellular domain. This implies that all leptin receptor isoforms sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997faeaedf0502a8a9523cdd2819bedb
https://doi.org/10.1093/jn/128.12.2299
https://doi.org/10.1093/jn/128.12.2299