Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Richard J. Hershcopf"'
Autor:
Barnett Zumoff, Gladys W. Strain, Lorraine K. Miller, Robert S. Rosenfeld, William Rosner, Charles D. Levit, Richard J. Hershcopf, Marcia F. Kalin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 66:1019-1023
To study the ability of weight loss to reverse the hyperestrogenemia-induced hypogonadotropic hypogonadism that occurs in obese men, we measured the 24-h mean plasma free and total estradiol (E2), total estrone, FSH, LH, and free and total testostero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630f3c0b3f66e2773f1104f8dfd647d2
https://doi.org/10.1210/jcem-66-5-1019
https://doi.org/10.1210/jcem-66-5-1019
Autor:
Denis C. Muller, Roger H Unger, M. Nagulesparan, Jordan D. Tobin, Dariush Elahi, Arthur H. Rubenstein, Richard J. Hershcopf, Petra M. Blix, Reubin Andres
Publikováno v:
New England Journal of Medicine. 306:1196-1202
We investigated the possible existence of a negative short-loop feedback of circulating insulin on the parent beta cell in 10 lean Caucasians, 10 obese Caucasians, and 10 obese Pima Indians. Plasma insulin levels were raised acutely by 100 microunits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f7d92a2b3e2a2defa6393dcadba76e
https://doi.org/10.1056/nejm198205203062002
https://doi.org/10.1056/nejm198205203062002
Publikováno v:
Steroids. 52:69-83
Premenopausal female smokers show significantly increased estrogen 2-hydroxylation, which may account in part for the anti-estrogenic effects of cigarette smoking. We have measured five major urinary estrogens, including estradiol (E2), estrone (E1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9410011c317d72e95ee50baa7b7737
https://doi.org/10.1016/0039-128x(88)90218-8
https://doi.org/10.1016/0039-128x(88)90218-8
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 61:1071-1075
Fatty acid esters of estradiol coupled at the C-17 position are naturally occurring metabolites of estradiol (E2). They have been recovered after incubation of E2 with human tissue and identified in human plasma. We investigated the primary metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef16e713b627a131177217c532ea924
https://doi.org/10.1210/jcem-61-6-1071
https://doi.org/10.1210/jcem-61-6-1071
Autor:
Michael P. Osborne, Jack Fishman, Lone A. Kourides, Paul Peter Rosen, Wick R. Williams, Rashida A. Karmali, Richard J. Hershcopf, H. Leon Bradlow
Publikováno v:
Cancer Investigation. 6:629-631
A collaborative program is exploring potential endocrine biomarkers of breast cancer risk and the effects of omega-3 fatty acids and levothyroxine on these biomarkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b17c5da23e201707b1992bac94814d
https://doi.org/10.3109/07357908809082132
https://doi.org/10.3109/07357908809082132
Publikováno v:
The Journal of clinical endocrinology and metabolism. 62(1)
We sought to test the hypothesis that in man, the fraction of estradiol (E2) that does not undergo oxidation to estrone (E1) in vivo is not available for subsequent hydroxylation at C-2 and C-16 alpha. Using radiometric methods, the extent of 17-oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f227004a78005227b0d203e823353679
https://pubmed.ncbi.nlm.nih.gov/3940266
https://pubmed.ncbi.nlm.nih.gov/3940266
Publikováno v:
Annals of the New York Academy of Sciences. 464
From these results we may conclude that estradiol 16 alpha-hydroxylation is highly correlated with tumor incidence, and that the reaction is partly regulated by MMTV and the rest by genetic influences. Elevated hydroxylation appears to be an autosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3eb190e120baa1ee07f201b030c40b
https://pubmed.ncbi.nlm.nih.gov/3014947
https://pubmed.ncbi.nlm.nih.gov/3014947
Autor:
Dariush Elahi, Gary S. Raizes, Howard L. Baldwin, Douglas D. Schocken, Reubin Andres, Richard J. Hershcopf, Jordan D. Tobin
Publikováno v:
Journal of chronic diseases. 35(2)
Serum cholesterol levels were determined in 1011 male participants of the Baltimore Longitudinal Study of Aging. This study presents the longitudinal changes in serum cholesterol from 1 July 1963 to 30 June 1977. Serum cholesterol values dropped 6% b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bef136aa250bf8c1f9112a9f4ec2bb
https://pubmed.ncbi.nlm.nih.gov/7056835
https://pubmed.ncbi.nlm.nih.gov/7056835
Publikováno v:
Journal of steroid biochemistry. 20(4B)
We have measured the three principal oxidative transformations of estradiol by means of a radiometric procedure in women with breast or endometrial cancer and in age matched controls. No difference between the 17 beta-ol oxidation or 2-hydroxylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cd7f2cbc392257618352e8da4ce76e
https://pubmed.ncbi.nlm.nih.gov/6727352
https://pubmed.ncbi.nlm.nih.gov/6727352
Publikováno v:
Metabolism: clinical and experimental. 38(6)
Studies of steroids and plasma lipoproteins in male cigarette smokers reveal that smoking is associated with an increase in peripheral estrogens and a decrease in high-density lipoprotein-cholesterol (HDL-C). We hypothesized that the lower HDL-C in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bf5ba3af73a5c8cec1e7a8f954277c
https://pubmed.ncbi.nlm.nih.gov/2725292
https://pubmed.ncbi.nlm.nih.gov/2725292