Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Richard J. Gulizia"'
Autor:
Jill Wilken, Robin E. Offord, Richard J. Gulizia, Darren A. Thompson, Pascal Poignard, Laurent Picard, Rebecca Sabbe, Donald E. Mosier, Gaston Picchio
Publikováno v:
Journal of Virology. 73:3544-3550
The natural ligands for the CCR5 chemokine receptor, macrophage inflammatory protein 1α (MIP-1α), MIP-1β, and RANTES (regulated on T-cell activation, normal T-cell expressed and secreted), are known to inhibit human immunodeficiency virus (HIV) en
Publikováno v:
Journal of Virology. 71:4161-4164
The pathogenicity of four human immunodeficiency virus type 1 (HIV-1) isolates with nef deleted for SCID mice repopulated with human peripheral blood leukocytes (hu-PBL-SCID mice) was studied. Deletion of nef led to a substantial reduction in CD4-pos
Publikováno v:
Science. 260:689-692
Human immunodeficiency virus (HIV) isolates differ in cell tropism, replication, pathogenicity, and syncytial induction in vitro. CD4+ T cells were enumerated in severe combined immunodeficient mice transplanted with human peripheral blood leukocytes
Publikováno v:
The Journal of Experimental Medicine
The autosomal recessive scid mutation results in defective immunoglobulin and T cell receptor gene rearrangement. The scid mutation occurred in the allotype congenic C.B-17 line, and up to 25% of C.B-17 scid mice spontaneously produce both T cells an
Autor:
Donald E. Mosier, Deborah H. Spector, Stephen M. Baird, Darcy B. Wilson, Stephen A. Spector, Richard J. Gulizia
Publikováno v:
Science. 251:791-794
Severe combined immunodeficient (SCID) mice reconstituted with human peripheral blood leukocytes (hu-PBL-SCID mice) have inducible human immune function and may be useful as a small animal model for acquired immunodeficiency syndrome (AIDS) research.
Autor:
Joel M. Gottesfeld, Donald E. Mosier, Richard J. Gulizia, John W. Trauger, Eldon E. Baird, Peter B. Dervan, Liliane A. Dickinson
Sequence-specific DNA-binding small molecules that can permeate human cells potentially could regulate transcription of specific genes. Multiple cellular DNA-binding transcription factors are required by HIV type 1 for RNA synthesis. Two pyrrole–im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4069499f754935aabaffbf6e00669b0
https://europepmc.org/articles/PMC23643/
https://europepmc.org/articles/PMC23643/
Most individuals infected with human immunodeficiency virus type 1 (HIV-1) initially harbor macrophage-tropic, non-syncytium-inducing (M-tropic, NSI) viruses that may evolve into T-cell-tropic, syncytium-inducing viruses (T-tropic, SI) after several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da4c98ec1c5a3df6bae24c8cfb91b2e
https://europepmc.org/articles/PMC110051/
https://europepmc.org/articles/PMC110051/
Autor:
Rebecca Sabbe, Brian G. Herndier, Gaston Picchio, Richard J. Gulizia, Donald E. Mosier, Michael S. McGrath
Publikováno v:
Virology. 238(1)
The body-cavity-based lymphoma cell line BCBL-1, which is infected with Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8, was injected alone or with human peripheral blood mononuclear cells into SCID mice. Immunoblastic lymphomas developed
Publikováno v:
Journal of virology. 71(9)
Individuals homozygous for a 32-bp deletion (delta 32) in the CCR5 gene encoding the coreceptor for macrophage-tropic human immunodeficiency virus type 1 (HIV-1) are resistant to virus infection, and heterozygous individuals show some slowing of dise
Publikováno v:
Journal of virology. 70(6)
We have used envelope recombinant viruses generated between two molecular clones of human immunodeficiency virus type 1 (HIV-1), T-cell-tropic HIV-1SF2 and macrophage-tropic HIV-1SF162, to assess pathogenic potential in the human peripheral blood leu