Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Richard J. Goebel"'
Autor:
P. G. Canonico, Roland K. Robins, Richard J. Goebel, Alexander D. Adams, P. A. Mckernan, Byron K. Murray, Ganapathi R. Revankar
Publikováno v:
Journal of Medicinal Chemistry. 25:1334-1338
Following our recent discovery that 9-beta-D-ribofuranosylpurine-6-carboxamide (1) exhibits potent antiviral activity, we were prompted to synthesize certain pyrrolopyrimidine and pyrazolopyrimidine nucleosides containing a carbamoyl function (7a,b a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740a3aa5e03b02bf63a8e16ebb7c2d33
https://doi.org/10.1021/jm00353a012
https://doi.org/10.1021/jm00353a012
Synthesis and biological activity of certain 3,4-disubstituted pyrazolo[3,4-d]pyrimidine nucleosides
Autor:
P. A. Mckernan, C. R. Petrie, R. B. Davidson, Richard J. Goebel, G. R. Revankar, N. K. Dalley, Howard B. Cottam, Roland K. Robins
Publikováno v:
Journal of Medicinal Chemistry. 27:1119-1127
A number of 3,4-disubstituted pyrazolo[3,4-d]pyrimidine ribonucleosides were synthesized and tested for their biological activity. Glycosylation of persilylated as well as nonsilylated 3-bromoallopurinol with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c858ba8f3edb2a4b225cc6eb7fefd8c
https://doi.org/10.1021/jm00375a006
https://doi.org/10.1021/jm00375a006
Publikováno v:
Journal of Pharmaceutical Sciences. 71:1062-1064
Three analogs of thyroliberin (I) were prepared. These compounds, N-m-chloroacetylbenzoyl-phenylalanyl-prolineamide (VIa), N-p-chloroacetylbenzoyl-phenylalanyl-prolineamide (VIb) and N-chloroacetyl-alanyl-phenylalanyl-prolineamide (IX), were designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad24f062f3ac3e7642455c56c4c1f91
https://doi.org/10.1002/jps.2600710928
https://doi.org/10.1002/jps.2600710928
Publikováno v:
Chemischer Informationsdienst. 12
Six analogues of thyroliberin (TRH) that have a chloroacetyl substituent at the amino terminus have been prepared as potential affinity labels for the TRH receptor. These compounds are N-(chloroacetyl)-L-alanyl-L-phenylalanylpyrrolidine (ClAc-Ala-Phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19531a42ba9f69f8ea102e73b4e2e327
https://doi.org/10.1002/chin.198134316
https://doi.org/10.1002/chin.198134316
Autor:
Howard B. Cottam, G. R. Revankar, Roland K. Robins, N. K. Dalley, C. R. Petrie, R. B. Davidson, P. A. Mckernan, Richard J. Goebel
Publikováno v:
Chemischer Informationsdienst. 16
A number of 3,4-disubstituted pyrazolo[3,4-d]pyrimidine ribonucleosides were synthesized and tested for their biological activity. Glycosylation of persilylated as well as nonsilylated 3-bromoallopurinol with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fad9a5f403aee9db604b969065be504
https://doi.org/10.1002/chin.198505343
https://doi.org/10.1002/chin.198505343
Publikováno v:
Life sciences. 30(9)
The effects of several analogs of thyroliberin (TRH), that have a chloro-acetyl substituent at the amino terminus, on locomotor depressant, locomotor stimulant, hyperthermic and hypothermic response to morphine were determined in the mouse. These com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7d4e5accf4269600786624d853a404
https://pubmed.ncbi.nlm.nih.gov/6803094
https://pubmed.ncbi.nlm.nih.gov/6803094
Autor:
P. A. Mckernan, Byron K. Murray, P. G. Canonico, Richard J. Goebel, Ganapathi R. Revankar, Alexander D. Adams, Roland K. Robins
Publikováno v:
Chemischer Informationsdienst. 14
Following our recent discovery that 9-beta-D-ribofuranosylpurine-6-carboxamide (1) exhibits potent antiviral activity, we were prompted to synthesize certain pyrrolopyrimidine and pyrazolopyrimidine nucleosides containing a carbamoyl function (7a,b a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2798c249cf77a55655e1eb5f55137ee4
https://doi.org/10.1002/chin.198317331
https://doi.org/10.1002/chin.198317331
Publikováno v:
Journal of medicinal chemistry. 24(4)
Six analogues of thyroliberin (TRH) that have a chloroacetyl substituent at the amino terminus have been prepared as potential affinity labels for the TRH receptor. These compounds are N-(chloroacetyl)-L-alanyl-L-phenylalanylpyrrolidine (ClAc-Ala-Phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f25cf5f6297df14972ad6d3725c89f7
https://pubmed.ncbi.nlm.nih.gov/6267279
https://pubmed.ncbi.nlm.nih.gov/6267279