Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Richard J. Focht"'
Autor:
Richard J. Focht, Bruce D. Car, Nancy R. Contel, Joseph E. Dinchuk, Stewart A. Gorry, Jennifer J. Johnston, Bruce D. Jaffee, James M. Trzaskos, Robert Collins, Vicki M. Eng, Maryanne B. Covington, P. M. Czerniak
Publikováno v:
Nature. 378:406-409
Prostaglandins have wide-ranging effects in the body and are thought to be important mediators of inflammation. Cyclooxygenase (COX) plays a key regulatory role in prostaglandin synthesis, and occurs in both constitutive (COX-1) and inducible (COX-2)
Autor:
Daniel D. Carson, Richard J. Focht, Jay L. Vivian, Shaila G. Parker, Daniel S. Oristian, Catherine B. Kirn-Safran
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 236(2)
Because of their deleterious effects on developing organisms, ribosomal protein (RP) mutations have been poorly described in mammals, and only a few heterozygous mutations have been shown to be viable. This observation is believed to be due to the fa
Autor:
Richard Wynn, Mark J Rupar, Jennifer A. Kelley, Timothy C. Burn, Nina I. Zolotarjova, Nancy L. Henderson, John Link, Jianhong Ma, Paul A. Friedman, Bernard H. Selling, Robert B. Stein, Joseph E. Dinchuk, Mark R. Cunningham, Reid M. Huber, Nicola T. Neff, Richard J. Focht, Gregory F Hollis, Andrew A. Stern
Publikováno v:
The Journal of biological chemistry. 277(15)
The BAH genomic locus encodes three distinct proteins: junctin, humbug, and BAH. All three proteins share common exons, but differ significantly based upon the use of alternative terminal exons. The biological roles of BAH and humbug and their functi
Autor:
Siew Peng Ho, Paul A. Friedman, Richard J. Focht, Joseph E. Dinchuk, Nancy L. Henderson, Timothy Burn, Jeannine M. Hollis, Reid Huber, Karyn T. O'Neil, John Link, Gregory Hollis, Michael Scully
Publikováno v:
The Journal of biological chemistry. 275(50)
The mouse aspartyl beta-hydroxylase gene (Asph, BAH) has been cloned and characterized. The mouse BAH gene spans 200 kilobase pairs of genomic DNA and contains 24 exons. Of three major BAH-related transcripts, the two largest (6,629 and 4,419 base pa
Publikováno v:
The Journal of biological chemistry. 271(1)
Several lines of transgenic mice were generated with either active or inactive forms of the human immunodeficiency virus type 1 (HIV-1) protease gene under the control of the mouse lens alpha A-crystallin promoter. Mice bearing the inactive protease
Autor:
Catherine B. Kirn‐Safran, Daniel S. Oristian, Richard J. Focht, Shaila G. Parker, Jay L. Vivian, Daniel D. Carson
Publikováno v:
Developmental Dynamics; Feb2007, Vol. 236 Issue 2, p447-460, 14p
Publikováno v:
Annals of the New York Academy of Sciences. 460:202-213
Publikováno v:
Cell. 30:373-383
Regulation of cartilage extracellular matrix synthesis has been examined in chondroblasts infected with a temperature-sensitive mutant of Rous sarcoma virus. Cells grown at the nonpermissive temperature synthesized large amounts of several chondrobla