Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Richard J. Elsworthy"'
Autor:
Richard J. Elsworthy, Stephanie T. Jong, Sarah Hanson, Oliver M. Shannon, Amy Jennings, Rachel Gillings, Mario Siervo, Michael Hornberger, Wendy Hardeman, John C. Mathers, Anne-Marie Minihane, Sarah Aldred
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionPhysical inactivity and sedentary behaviour are linked to increased risk of cardiovascular disease, infections and dementia, as well as placing a significant economic burden on healthcare systems. The implementation of COVID-19 pandemic l
Externí odkaz:
https://doaj.org/article/33254488a79d4d8486dfb4dfbde0fa9f
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Much of the early research into AD relies on a neuron-centric view of the brain, however, evidence of multiple altered cellular interactions between glial cells and the vasculature early in AD has been demonstrated. As such, alterations in astrocyte
Externí odkaz:
https://doaj.org/article/92068887c83f4850a6d8e3980cc8aaa9
Publikováno v:
Aging and Health Research, Vol 2, Iss 3, Pp 100093- (2022)
With advancements in our ability to treat or manage more diseases than ever, people are able to live longer in greater health. However, for individuals who develop Alzheimer's disease (AD), therapeutic options are currently limited to symptom managem
Externí odkaz:
https://doaj.org/article/6dedd4fdea0049bf82d525fe0db3ba8d
Autor:
Richard J. Elsworthy, Sarah Aldred
Publikováno v:
Oxidative Eustress in Exercise Physiology ISBN: 9781003051619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5993f1be290bcef2148e293328d4e1c0
https://doi.org/10.1201/9781003051619-16
https://doi.org/10.1201/9781003051619-16
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry
Translational Psychiatry
First-episode psychosis (FEP) is a psychiatric disorder, characterised by positive and negative symptoms, usually emerging during adolescence and early adulthood. FEP represents an early intervention opportunity for intervention in psychosis. Redox d
Autor:
Adele Ludlam, Eric J. Hill, Marianne C. King, Sarah Alqattan, Emily Fisher, James A Crowe, Richard J Elsworthy, Alastair Grainger, Sarah Aldred
Publikováno v:
Molecular and cellular neurosciences. 114
Introduction Presenilin-1 (PSEN1) gene mutations are the most common cause of familial Alzheimer's disease (fAD) and are known to interfere with activity of the membrane imbedded γ-secretase complex. PSEN1 mutations have been shown to shift Amyloid-
Autor:
Richard J Elsworthy, Sarah Aldred
Publikováno v:
Journal of Alzheimer's disease : JAD. 69(3)
Depression is a common co-morbidity seen in people with Alzheimer's disease (AD). However, the successful treatment of depressive symptoms in people with AD is rarely seen. In fact, multiple randomized controlled trials have shown selective serotonin
Autor:
Richard J Elsworthy, Sarah Aldred
Publikováno v:
Experimental Gerontology. 132:110838
Advancing age is a major risk factor for a range of diseases such as, cardiovascular disease, diabetes, cancer and neurodegenerative diseases. In addition, over a third of the population are overweight and obesity is becoming more prevalent in younge